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The map label for this gene is uvrC [H]

Identifier: 213691965

GI number: 213691965

Start: 1267767

End: 1270133

Strand: Direct

Name: uvrC [H]

Synonym: Blon_1083

Alternate gene names: 213691965

Gene position: 1267767-1270133 (Clockwise)

Preceding gene: 213691964

Following gene: 213691966

Centisome position: 44.75

GC content: 62.61

Gene sequence:

>2367_bases
ATGACGAACGATATTGAGCGGCATAGTCCGGATGAGTGGCGGAAGACTGCGGCGGCGTTAATGCCGGAAAGCGTAGCTGT
GGGTGCCGGGGAAACGACGGCGAAGGTGAATGCGAATGGGGCACCTTTGCTGGGGGATTCTCGCGACCTGTTCCGACCCA
AGACCTCGGATATTCCCACCAAACCCGGTGTGTACAAATGGCGCGACGGGGAAGGGCGCGTCATTTATGTGGGCAAGGCG
AAGAACCTGCGCAACAGGCTCACCAATTATTTCCAGCCGCTGTATCTGCTGCATCCGCGCACGCAGACCATGGTGCTGAC
CGCACGCAGTCTGGAGTGGACGGTCGTCGCCACCGAACTGGAATCACTGACGTTGGAATACACGTGGATCAAGGAATTCG
ACCCACGGTTCAACGTGCAGTTCCGCGACGACAAGACCTATCCGTATCTCGCGGTCAGCACGGGGGAGCGAATTCCGCGC
GTGTGGGTCACTCGGTCGCGCAAACGTCGGGATACCCGGTATTTCGGCCCCTATGCCAAAGTATGGGAATTACGGCACAG
CCTTGACCGGCTGTTGCGCACGTTCCCGGTCCGCACCTGCACCACCAGCGTATTCCACAAGGCGCAACTGACCGGACGGC
CATGCCTGTTCGCCTCCATCGGCAAATGCTCCGCACCCTGCGTGAACCGTATCGAAGCGGACGAACACCGGCGGCTGTGC
GAACAGCTGGTCGGCGTGATGACCGGACGACTCGGACGGCCCTACATCGCCCAGTTGACCCGCGACATGAAAGAGGCCAG
CGCCGAACTCGAATTCGAGAAAGCCGCCCGACTGCGCGACCAGATCCAAATGCTGGAAACCGTGGTGCAACAGAACGCCG
TCGTCTTCGACCAGGATGTGGACGCGGACGTGTTCGGCTTCGCCAGCGACGAGCTCGAAGCCTCAGTGCACGCCTTTTAT
GTGCGCGCCGGCTCGATTCGCGGCGAACGCAATTGGAGCGTCGAACGAGTTGAGGACATCGATGACGCCGACTTGATGGC
CGACCTTCTGGCGCAGGTGTATTCGGACGCCGCCGGGGACAATCACCCCCAGTCGGCCGCGACCATCTCCACCAATCGCG
AGGCCATCGGCTCCACGCAAACCATCACGGCCGCGGACGCTGTGGCACGCGCCCAGGCCACCCGAGAACGCAACACCCGT
CAGGAGACCACCGGACGCGCGGACCTGCTGGCACCCATCGCACCGGTACCGCGCGAAATCATCGTGCCCGTCGAACCGGC
CCGCCGTGAGGAACTCGAAGGCTGGCTGACCAATCTGCGCGGGGGAGCGGTGACCATCCGTGTGGCCTCGCGAGGCGACA
AGAAGCAGCTCATGGGCCGCGCCAATGAGAACGCCAGCCAAGCACTGCAGCGCAGCAAGATGAGCCGCATCTCCGACATG
GGCGCACGCACCCAGGCCATGAACGATGTGGCCAAGGCATTGGGACTCGCGGAAGCCCCGCTGCGCATCGAATGCTACGA
CATTTCGAACACTGTGGGCGGTGCCTTCCAGGTGTCCTCCATGGTGGTGTTCGAAGACGCGATCGCCAAGAAATCCGAAT
ACCGACGCTTCGCCATCCGAGGCAAGGACGGCAAAGGCGCGGTGGGTGATCTGTCCGCACTTTACGAGACGCTCACCCGC
CGCTTCAAGCACGGCAACATCGCCGGCGACTCCGGCGAAAGCATCGACGCGGAACAGCGCGCGGCCTCGGCCGCCGGCAA
GATGACCACTGCCGTGGCGGCGGAGACAATCGCTGCGAACGGTAACGACAATGGTGAGAACGGTTCCGACATCAGTGGCA
AGGGGCACGCGGTGCCGGACGGAGTGCAGAACGATACACGGGAAACTTCGCCCGACATCGTCCAGCAGAACACAAACCGG
CATCACTTTGCCTACAAGCCGAACCTGGTGGTGGTCGACGGCGGCAAGCCGCAGGTCATGGCCGCCGCCAAGGCGCTCGA
GGACTGTGGCGTGAACGACGTGGCCGTCTGCGGACTGGCCAAACGCTTGGAAGAGGTGTGGGTGCCGGACGACGACTATC
CGATCATCCTCAAACGCCAGTCCGAAGGCATGTATCTGCTGCAGCGTGTACGCGACGAATCCCACCGCTTCGCCATCACC
TACCACCGCCAACAGCGGCGCAAAGGCGCCCTGCGCAGCGCGCTCGACGAGATTCCAGGCATCGGCAAAAGCTACCAGAA
GCGGCTGCTCAACCACTTCGGCTCGGTCAAAGCCATGCGCGAAGCCAGTGTCGAGGACTTCGAGAAGGTCAAAGGCATCG
GCCACGCCAAAGCCGAAGCGCTGTACAACGCGCTGCACGAGCAGTGA

Upstream 100 bases:

>100_bases
ATGCTCCGGGCCGCTCAGGCCAAGTCTTTACGGTCCAGCAACACACACCCCAACCCACCCAATCCCTGATGATTGGTTTT
GCTTAATAGCGAGGAGGATT

Downstream 100 bases:

>100_bases
GCCGGCCCGGTCCAGCAGCCCAGAGTGAATTTTCGGTTGCGGGGCCTGTGGTTGACATATTCGAAGCAAAGTGTCGGCTA
GCATGGGAACAGACATCAAG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 788; Mature: 787

Protein sequence:

>788_residues
MTNDIERHSPDEWRKTAAALMPESVAVGAGETTAKVNANGAPLLGDSRDLFRPKTSDIPTKPGVYKWRDGEGRVIYVGKA
KNLRNRLTNYFQPLYLLHPRTQTMVLTARSLEWTVVATELESLTLEYTWIKEFDPRFNVQFRDDKTYPYLAVSTGERIPR
VWVTRSRKRRDTRYFGPYAKVWELRHSLDRLLRTFPVRTCTTSVFHKAQLTGRPCLFASIGKCSAPCVNRIEADEHRRLC
EQLVGVMTGRLGRPYIAQLTRDMKEASAELEFEKAARLRDQIQMLETVVQQNAVVFDQDVDADVFGFASDELEASVHAFY
VRAGSIRGERNWSVERVEDIDDADLMADLLAQVYSDAAGDNHPQSAATISTNREAIGSTQTITAADAVARAQATRERNTR
QETTGRADLLAPIAPVPREIIVPVEPARREELEGWLTNLRGGAVTIRVASRGDKKQLMGRANENASQALQRSKMSRISDM
GARTQAMNDVAKALGLAEAPLRIECYDISNTVGGAFQVSSMVVFEDAIAKKSEYRRFAIRGKDGKGAVGDLSALYETLTR
RFKHGNIAGDSGESIDAEQRAASAAGKMTTAVAAETIAANGNDNGENGSDISGKGHAVPDGVQNDTRETSPDIVQQNTNR
HHFAYKPNLVVVDGGKPQVMAAAKALEDCGVNDVAVCGLAKRLEEVWVPDDDYPIILKRQSEGMYLLQRVRDESHRFAIT
YHRQQRRKGALRSALDEIPGIGKSYQKRLLNHFGSVKAMREASVEDFEKVKGIGHAKAEALYNALHEQ

Sequences:

>Translated_788_residues
MTNDIERHSPDEWRKTAAALMPESVAVGAGETTAKVNANGAPLLGDSRDLFRPKTSDIPTKPGVYKWRDGEGRVIYVGKA
KNLRNRLTNYFQPLYLLHPRTQTMVLTARSLEWTVVATELESLTLEYTWIKEFDPRFNVQFRDDKTYPYLAVSTGERIPR
VWVTRSRKRRDTRYFGPYAKVWELRHSLDRLLRTFPVRTCTTSVFHKAQLTGRPCLFASIGKCSAPCVNRIEADEHRRLC
EQLVGVMTGRLGRPYIAQLTRDMKEASAELEFEKAARLRDQIQMLETVVQQNAVVFDQDVDADVFGFASDELEASVHAFY
VRAGSIRGERNWSVERVEDIDDADLMADLLAQVYSDAAGDNHPQSAATISTNREAIGSTQTITAADAVARAQATRERNTR
QETTGRADLLAPIAPVPREIIVPVEPARREELEGWLTNLRGGAVTIRVASRGDKKQLMGRANENASQALQRSKMSRISDM
GARTQAMNDVAKALGLAEAPLRIECYDISNTVGGAFQVSSMVVFEDAIAKKSEYRRFAIRGKDGKGAVGDLSALYETLTR
RFKHGNIAGDSGESIDAEQRAASAAGKMTTAVAAETIAANGNDNGENGSDISGKGHAVPDGVQNDTRETSPDIVQQNTNR
HHFAYKPNLVVVDGGKPQVMAAAKALEDCGVNDVAVCGLAKRLEEVWVPDDDYPIILKRQSEGMYLLQRVRDESHRFAIT
YHRQQRRKGALRSALDEIPGIGKSYQKRLLNHFGSVKAMREASVEDFEKVKGIGHAKAEALYNALHEQ
>Mature_787_residues
TNDIERHSPDEWRKTAAALMPESVAVGAGETTAKVNANGAPLLGDSRDLFRPKTSDIPTKPGVYKWRDGEGRVIYVGKAK
NLRNRLTNYFQPLYLLHPRTQTMVLTARSLEWTVVATELESLTLEYTWIKEFDPRFNVQFRDDKTYPYLAVSTGERIPRV
WVTRSRKRRDTRYFGPYAKVWELRHSLDRLLRTFPVRTCTTSVFHKAQLTGRPCLFASIGKCSAPCVNRIEADEHRRLCE
QLVGVMTGRLGRPYIAQLTRDMKEASAELEFEKAARLRDQIQMLETVVQQNAVVFDQDVDADVFGFASDELEASVHAFYV
RAGSIRGERNWSVERVEDIDDADLMADLLAQVYSDAAGDNHPQSAATISTNREAIGSTQTITAADAVARAQATRERNTRQ
ETTGRADLLAPIAPVPREIIVPVEPARREELEGWLTNLRGGAVTIRVASRGDKKQLMGRANENASQALQRSKMSRISDMG
ARTQAMNDVAKALGLAEAPLRIECYDISNTVGGAFQVSSMVVFEDAIAKKSEYRRFAIRGKDGKGAVGDLSALYETLTRR
FKHGNIAGDSGESIDAEQRAASAAGKMTTAVAAETIAANGNDNGENGSDISGKGHAVPDGVQNDTRETSPDIVQQNTNRH
HFAYKPNLVVVDGGKPQVMAAAKALEDCGVNDVAVCGLAKRLEEVWVPDDDYPIILKRQSEGMYLLQRVRDESHRFAITY
HRQQRRKGALRSALDEIPGIGKSYQKRLLNHFGSVKAMREASVEDFEKVKGIGHAKAEALYNALHEQ

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=298, Percent_Identity=36.5771812080537, Blast_Score=197, Evalue=3e-51,
Organism=Escherichia coli, GI1788037, Length=189, Percent_Identity=25.3968253968254, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 87465; Mature: 87333

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDIERHSPDEWRKTAAALMPESVAVGAGETTAKVNANGAPLLGDSRDLFRPKTSDIPT
CCCCCCCCCCHHHHHHHHHHCCCHHEECCCCCEEEECCCCCCCCCCCHHHCCCCCCCCCC
KPGVYKWRDGEGRVIYVGKAKNLRNRLTNYFQPLYLLHPRTQTMVLTARSLEWTVVATEL
CCCCEEEECCCCCEEEEECCHHHHHHHHHHHCCEEEECCCCCEEEEEECCCEEEEEEEEH
ESLTLEYTWIKEFDPRFNVQFRDDKTYPYLAVSTGERIPRVWVTRSRKRRDTRYFGPYAK
HHEEEEEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCHHHHHCCHHHCCCCCCCCHHH
VWELRHSLDRLLRTFPVRTCTTSVFHKAQLTGRPCLFASIGKCSAPCVNRIEADEHRRLC
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCHHHHHHH
EQLVGVMTGRLGRPYIAQLTRDMKEASAELEFEKAARLRDQIQMLETVVQQNAVVFDQDV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
DADVFGFASDELEASVHAFYVRAGSIRGERNWSVERVEDIDDADLMADLLAQVYSDAAGD
CCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
NHPQSAATISTNREAIGSTQTITAADAVARAQATRERNTRQETTGRADLLAPIAPVPREI
CCCCCCEEECCCHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCCCCE
IVPVEPARREELEGWLTNLRGGAVTIRVASRGDKKQLMGRANENASQALQRSKMSRISDM
EECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
GARTQAMNDVAKALGLAEAPLRIECYDISNTVGGAFQVSSMVVFEDAIAKKSEYRRFAIR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCEEEEE
GKDGKGAVGDLSALYETLTRRFKHGNIAGDSGESIDAEQRAASAAGKMTTAVAAETIAAN
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GNDNGENGSDISGKGHAVPDGVQNDTRETSPDIVQQNTNRHHFAYKPNLVVVDGGKPQVM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCEEEEECCCCHHH
AAAKALEDCGVNDVAVCGLAKRLEEVWVPDDDYPIILKRQSEGMYLLQRVRDESHRFAIT
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEE
YHRQQRRKGALRSALDEIPGIGKSYQKRLLNHFGSVKAMREASVEDFEKVKGIGHAKAEA
ECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
LYNALHEQ
HHHHHHCC
>Mature Secondary Structure 
TNDIERHSPDEWRKTAAALMPESVAVGAGETTAKVNANGAPLLGDSRDLFRPKTSDIPT
CCCCCCCCCHHHHHHHHHHCCCHHEECCCCCEEEECCCCCCCCCCCHHHCCCCCCCCCC
KPGVYKWRDGEGRVIYVGKAKNLRNRLTNYFQPLYLLHPRTQTMVLTARSLEWTVVATEL
CCCCEEEECCCCCEEEEECCHHHHHHHHHHHCCEEEECCCCCEEEEEECCCEEEEEEEEH
ESLTLEYTWIKEFDPRFNVQFRDDKTYPYLAVSTGERIPRVWVTRSRKRRDTRYFGPYAK
HHEEEEEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCHHHHHCCHHHCCCCCCCCHHH
VWELRHSLDRLLRTFPVRTCTTSVFHKAQLTGRPCLFASIGKCSAPCVNRIEADEHRRLC
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCHHHHHHH
EQLVGVMTGRLGRPYIAQLTRDMKEASAELEFEKAARLRDQIQMLETVVQQNAVVFDQDV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
DADVFGFASDELEASVHAFYVRAGSIRGERNWSVERVEDIDDADLMADLLAQVYSDAAGD
CCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
NHPQSAATISTNREAIGSTQTITAADAVARAQATRERNTRQETTGRADLLAPIAPVPREI
CCCCCCEEECCCHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCCCCE
IVPVEPARREELEGWLTNLRGGAVTIRVASRGDKKQLMGRANENASQALQRSKMSRISDM
EECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
GARTQAMNDVAKALGLAEAPLRIECYDISNTVGGAFQVSSMVVFEDAIAKKSEYRRFAIR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCEEEEE
GKDGKGAVGDLSALYETLTRRFKHGNIAGDSGESIDAEQRAASAAGKMTTAVAAETIAAN
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GNDNGENGSDISGKGHAVPDGVQNDTRETSPDIVQQNTNRHHFAYKPNLVVVDGGKPQVM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCEEEEECCCCHHH
AAAKALEDCGVNDVAVCGLAKRLEEVWVPDDDYPIILKRQSEGMYLLQRVRDESHRFAIT
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEE
YHRQQRRKGALRSALDEIPGIGKSYQKRLLNHFGSVKAMREASVEDFEKVKGIGHAKAEA
ECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
LYNALHEQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA