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The map label for this gene is gcp [H]

Identifier: 213691907

GI number: 213691907

Start: 1205732

End: 1206775

Strand: Direct

Name: gcp [H]

Synonym: Blon_1019

Alternate gene names: 213691907

Gene position: 1205732-1206775 (Clockwise)

Preceding gene: 213691906

Following gene: 213691908

Centisome position: 42.56

GC content: 66.09

Gene sequence:

>1044_bases
ATGAGCGAACCGGTTGTACTGGGCATTGAATCCACCTGCGACGAAACCGCAGCCGCCATCGTACGCGGCCGCGAACTGCT
CTCCAACGTCGTGGCCTCATCCATGGAGGAACACGCGCGATACGGCGGCGTGATCCCCGAAATCGCCTCCCGTGCGCACG
CTGAGGCCTTCGTGCCATGCGTGTCCAAGGCGCTCGCCGACGCGAACATGACGTTGGCGGATGTGGACGCCATCGCCGTG
TCCGCCGGTCCCGGACTGGCCGGTTGCCTGGCCGTGGGCGTGTCCGGCGCCAAGGCGCTGGCCTGGGCTGCGAACAAGCC
GATTTACGGCATCAACCATGTGATCGGGCACATCGCCGTCACTCAGCTGCAGTTCGGCCCGTTCCCCAAGGACACGCTGG
CTCTGATTGTCTCCGGCGGCCACACCTCGCTGCTGCATGTGGAGGACATGCCGCGCAAGATCGATGTGGTGGGCACCACG
CTGGATGACGCGGCGGGGGAGTGCTTCGACAAAGTCGCCCGTCTGCTCGGCTTCCCGTATCCGGGCGGCCCGCGCATCGA
CCGCCACGGACAAAACGGCGACCCGCACGCCATCAAGGTGCCGATGGGTCTGACCCAAGGCAAGGCCGGTGCCGCGCACC
CGTATGATTTCAGTTTCTCCGGTGTCAAGACCGCCGTGGCCCGTTGGGTGGGAAGCGAGCAGGCCGCCGGCCATGAGATT
CCGGTGGACGACGTGTGCGCATCCCTGGCCGACTCCGTGGCCACCGTGCTAGCCCGTAAGTCCATGCGCGGCTGCCGGCA
GTACGATTCCAACACGCTGATCGTGGGCGGCGGCTTCTCCGCCAACTCGCAGCTGCGCGCCAAACTGCTCGAATTCGGCG
AGAGCTACGGCGTCGACGTCCGTATCCCGCAAATCAAGCTCTGCACCGACAACGGTGCCATGGTCGCCATGCTCGGCGTG
AACCTGGTCGAAGCCGGCGTGGCCCCCAGCGCCCCCGACTTCCCGATCGACTCCGCCATGCCCCTGACCAAGGTCTCGAT
GTAA

Upstream 100 bases:

>100_bases
ACCTGAAACCTAGGGTCGTGGGCTTTGCCGCCCCGCAGACGGCATCGGCGGACACTGAAGACATCACCAGCAAGCAAACG
GAGAAGAACGGAGAAGCACG

Downstream 100 bases:

>100_bases
GATTTGCACGGTATTCCCAAACTGATACTGGGAATACCGTGCCTCTCATCGGTGAATTGACAGTGACCTGTCTGCCTGAT
GTGAGTAGTGGTGAGGTCTT

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSEPVVLGIESTCDETAAAIVRGRELLSNVVASSMEEHARYGGVIPEIASRAHAEAFVPCVSKALADANMTLADVDAIAV
SAGPGLAGCLAVGVSGAKALAWAANKPIYGINHVIGHIAVTQLQFGPFPKDTLALIVSGGHTSLLHVEDMPRKIDVVGTT
LDDAAGECFDKVARLLGFPYPGGPRIDRHGQNGDPHAIKVPMGLTQGKAGAAHPYDFSFSGVKTAVARWVGSEQAAGHEI
PVDDVCASLADSVATVLARKSMRGCRQYDSNTLIVGGGFSANSQLRAKLLEFGESYGVDVRIPQIKLCTDNGAMVAMLGV
NLVEAGVAPSAPDFPIDSAMPLTKVSM

Sequences:

>Translated_347_residues
MSEPVVLGIESTCDETAAAIVRGRELLSNVVASSMEEHARYGGVIPEIASRAHAEAFVPCVSKALADANMTLADVDAIAV
SAGPGLAGCLAVGVSGAKALAWAANKPIYGINHVIGHIAVTQLQFGPFPKDTLALIVSGGHTSLLHVEDMPRKIDVVGTT
LDDAAGECFDKVARLLGFPYPGGPRIDRHGQNGDPHAIKVPMGLTQGKAGAAHPYDFSFSGVKTAVARWVGSEQAAGHEI
PVDDVCASLADSVATVLARKSMRGCRQYDSNTLIVGGGFSANSQLRAKLLEFGESYGVDVRIPQIKLCTDNGAMVAMLGV
NLVEAGVAPSAPDFPIDSAMPLTKVSM
>Mature_346_residues
SEPVVLGIESTCDETAAAIVRGRELLSNVVASSMEEHARYGGVIPEIASRAHAEAFVPCVSKALADANMTLADVDAIAVS
AGPGLAGCLAVGVSGAKALAWAANKPIYGINHVIGHIAVTQLQFGPFPKDTLALIVSGGHTSLLHVEDMPRKIDVVGTTL
DDAAGECFDKVARLLGFPYPGGPRIDRHGQNGDPHAIKVPMGLTQGKAGAAHPYDFSFSGVKTAVARWVGSEQAAGHEIP
VDDVCASLADSVATVLARKSMRGCRQYDSNTLIVGGGFSANSQLRAKLLEFGESYGVDVRIPQIKLCTDNGAMVAMLGVN
LVEAGVAPSAPDFPIDSAMPLTKVSM

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=348, Percent_Identity=29.8850574712644, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=28.3536585365854, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1789445, Length=322, Percent_Identity=39.1304347826087, Blast_Score=211, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=29.3577981651376, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17557464, Length=335, Percent_Identity=28.0597014925373, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=360, Percent_Identity=28.3333333333333, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6322891, Length=340, Percent_Identity=25.8823529411765, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20129063, Length=361, Percent_Identity=32.9639889196676, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=27.3273273273273, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35981; Mature: 35849

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPVVLGIESTCDETAAAIVRGRELLSNVVASSMEEHARYGGVIPEIASRAHAEAFVPC
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSKALADANMTLADVDAIAVSAGPGLAGCLAVGVSGAKALAWAANKPIYGINHVIGHIAV
HHHHHHCCCCEEEECCEEEEECCCCHHHHHHHCCCCHHHEEECCCCCCCHHHHHHHHHHH
TQLQFGPFPKDTLALIVSGGHTSLLHVEDMPRKIDVVGTTLDDAAGECFDKVARLLGFPY
EEEECCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
PGGPRIDRHGQNGDPHAIKVPMGLTQGKAGAAHPYDFSFSGVKTAVARWVGSEQAAGHEI
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
PVDDVCASLADSVATVLARKSMRGCRQYDSNTLIVGGGFSANSQLRAKLLEFGESYGVDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEE
RIPQIKLCTDNGAMVAMLGVNLVEAGVAPSAPDFPIDSAMPLTKVSM
ECCEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SEPVVLGIESTCDETAAAIVRGRELLSNVVASSMEEHARYGGVIPEIASRAHAEAFVPC
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSKALADANMTLADVDAIAVSAGPGLAGCLAVGVSGAKALAWAANKPIYGINHVIGHIAV
HHHHHHCCCCEEEECCEEEEECCCCHHHHHHHCCCCHHHEEECCCCCCCHHHHHHHHHHH
TQLQFGPFPKDTLALIVSGGHTSLLHVEDMPRKIDVVGTTLDDAAGECFDKVARLLGFPY
EEEECCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
PGGPRIDRHGQNGDPHAIKVPMGLTQGKAGAAHPYDFSFSGVKTAVARWVGSEQAAGHEI
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
PVDDVCASLADSVATVLARKSMRGCRQYDSNTLIVGGGFSANSQLRAKLLEFGESYGVDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEE
RIPQIKLCTDNGAMVAMLGVNLVEAGVAPSAPDFPIDSAMPLTKVSM
ECCEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]