Click here to switch to the map view.

The map label for this gene is pgsA2 [H]

Identifier: 213691836

GI number: 213691836

Start: 1117646

End: 1118296

Strand: Direct

Name: pgsA2 [H]

Synonym: Blon_0945

Alternate gene names: 213691836

Gene position: 1117646-1118296 (Clockwise)

Preceding gene: 213691835

Following gene: 213691837

Centisome position: 39.45

GC content: 58.68

Gene sequence:

>651_bases
ATGGATGAGAACACAATGGACAAGCAGTCATCGCCCAAATCATCGCTGTTCGACGGATGGAACGCGCCGCCGAACCTGGT
CACCTACTCGCGCATCGTACTCGTGGTGATTTTCCTGACACTCGACATTCTCGCCGGCGCCTGGGGTGAGAGCAACCTGA
CCATGCGCTGGGTCGCCGCGGTACTGTTCATCATCGCCGCGTCCACCGATAAGATCGACGGTTGGATGGCCCGCAAATAC
AATCAGGTCACCGAAATGGGCAAGCTCATGGATCCGATCGCGGACAAGCTGCTCACTTGCGGCGCAATGATTGTATGCTC
CGCGTTCGGCGAGCTCGGCTGGTGGGTGACCATCCTGTTCCTGATTCGCGAAATCGGTATCACCGTTATGCGCTTCTTCG
TCATGGAGCGTCCGGGCGGCAAGGTCATCGCCGCCGCATGGCCCGGCAAGCTCAAGACCGTATTCCAGTGCGTGGGTCTG
TCCATGCTGCTGCTGCCGTTCTGGTCATTGGGTAACGGACAGGCCACGCCGTTCTGGATGACCGCTTACTACTTCCTGAC
CTACGCCATCATCTACGTGGCATTGGTCCTGTGCCTCTACTCGGGTGCCGTGTACCTGTACAACACGTTCGTCGCCCCGA
AGCGGAAGTGA

Upstream 100 bases:

>100_bases
GCCACGCGGCCATCAGCACGCAACCTGATTCCCGAATAATAGCAGTCAATATCCAGCCACCACTCACTCAAGGTAGGAGT
ATGGGGGTAACGTGAACACT

Downstream 100 bases:

>100_bases
CGGATATTCCAATGCAGGAATTGTGCGACAGTCTCGCGGCCGGCATCCTCAAGATCTGCGAGGCGAACAATACGAAAATC
TCCTGCGCTGAATCCCTGAC

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MDENTMDKQSSPKSSLFDGWNAPPNLVTYSRIVLVVIFLTLDILAGAWGESNLTMRWVAAVLFIIAASTDKIDGWMARKY
NQVTEMGKLMDPIADKLLTCGAMIVCSAFGELGWWVTILFLIREIGITVMRFFVMERPGGKVIAAAWPGKLKTVFQCVGL
SMLLLPFWSLGNGQATPFWMTAYYFLTYAIIYVALVLCLYSGAVYLYNTFVAPKRK

Sequences:

>Translated_216_residues
MDENTMDKQSSPKSSLFDGWNAPPNLVTYSRIVLVVIFLTLDILAGAWGESNLTMRWVAAVLFIIAASTDKIDGWMARKY
NQVTEMGKLMDPIADKLLTCGAMIVCSAFGELGWWVTILFLIREIGITVMRFFVMERPGGKVIAAAWPGKLKTVFQCVGL
SMLLLPFWSLGNGQATPFWMTAYYFLTYAIIYVALVLCLYSGAVYLYNTFVAPKRK
>Mature_216_residues
MDENTMDKQSSPKSSLFDGWNAPPNLVTYSRIVLVVIFLTLDILAGAWGESNLTMRWVAAVLFIIAASTDKIDGWMARKY
NQVTEMGKLMDPIADKLLTCGAMIVCSAFGELGWWVTILFLIREIGITVMRFFVMERPGGKVIAAAWPGKLKTVFQCVGL
SMLLLPFWSLGNGQATPFWMTAYYFLTYAIIYVALVLCLYSGAVYLYNTFVAPKRK

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=144, Percent_Identity=36.1111111111111, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 24187; Mature: 24187

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDENTMDKQSSPKSSLFDGWNAPPNLVTYSRIVLVVIFLTLDILAGAWGESNLTMRWVAA
CCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VLFIIAASTDKIDGWMARKYNQVTEMGKLMDPIADKLLTCGAMIVCSAFGELGWWVTILF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIREIGITVMRFFVMERPGGKVIAAAWPGKLKTVFQCVGLSMLLLPFWSLGNGQATPFWM
HHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TAYYFLTYAIIYVALVLCLYSGAVYLYNTFVAPKRK
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCC
>Mature Secondary Structure
MDENTMDKQSSPKSSLFDGWNAPPNLVTYSRIVLVVIFLTLDILAGAWGESNLTMRWVAA
CCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VLFIIAASTDKIDGWMARKYNQVTEMGKLMDPIADKLLTCGAMIVCSAFGELGWWVTILF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIREIGITVMRFFVMERPGGKVIAAAWPGKLKTVFQCVGLSMLLLPFWSLGNGQATPFWM
HHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TAYYFLTYAIIYVALVLCLYSGAVYLYNTFVAPKRK
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]