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The map label for this gene is nrdR [H]

Identifier: 213691738

GI number: 213691738

Start: 994903

End: 995379

Strand: Direct

Name: nrdR [H]

Synonym: Blon_0844

Alternate gene names: 213691738

Gene position: 994903-995379 (Clockwise)

Preceding gene: 213691737

Following gene: 213691741

Centisome position: 35.12

GC content: 53.88

Gene sequence:

>477_bases
ATGGTTTTTCCGCCCGTACACGTTATTCTGGGGAGCATGCATTGTCCTTTTTGCCAGAACCCCGACACCAAAGTCATTGA
TACGCGCATTAGCGATGACGGTCATTCCATCCGTCGGCGTCGCGTATGCCCGAAATGCAACAAGCGTTTTACCACGGTGG
AAACCAGTATGCTGCTGGTCACTAAACGTTCGGGTGGCGTGGAGCCATTCAGCAGAGACAAAGTGATTTCCGGCGTACGC
AAAGCCTGCCAGGGGCGGCCGGTCAGAGAAGAGGATCTGAAGCTGCTGGGACAGAAAGTCGAAGAGGATCTTCGCTCCCG
AGGCCTTGCCGAAGTCACCTCAGACGAAGTGGGCAAAGCCATCCTGAAACCGTTGCGTGACTTGGATGTGGTGGCGTACC
TTCGATTCGCGAGTGTGTACCAGAACTTTGCAGGTCTGGAGGATTTCCAAAGCGCCATTGATGGTTTGCGTGAATAA

Upstream 100 bases:

>100_bases
ACGGTGGATGAACTGATTGCGTTGAACAATCTTGAGTCCGGATCATTGCAGGCCGGGCAGCGCATTATTGTTCCGGCTGA
GTAGATGAAACCCGATCGGC

Downstream 100 bases:

>100_bases
TATTCGAATGCCATGCACCGTGATATGCGAGTGATTCGCAAACCATGGTGCGCGCCAATCATGAAGCCCTGCACTTATGA
AAGAGACCCGTCAACGACGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MVFPPVHVILGSMHCPFCQNPDTKVIDTRISDDGHSIRRRRVCPKCNKRFTTVETSMLLVTKRSGGVEPFSRDKVISGVR
KACQGRPVREEDLKLLGQKVEEDLRSRGLAEVTSDEVGKAILKPLRDLDVVAYLRFASVYQNFAGLEDFQSAIDGLRE

Sequences:

>Translated_158_residues
MVFPPVHVILGSMHCPFCQNPDTKVIDTRISDDGHSIRRRRVCPKCNKRFTTVETSMLLVTKRSGGVEPFSRDKVISGVR
KACQGRPVREEDLKLLGQKVEEDLRSRGLAEVTSDEVGKAILKPLRDLDVVAYLRFASVYQNFAGLEDFQSAIDGLRE
>Mature_158_residues
MVFPPVHVILGSMHCPFCQNPDTKVIDTRISDDGHSIRRRRVCPKCNKRFTTVETSMLLVTKRSGGVEPFSRDKVISGVR
KACQGRPVREEDLKLLGQKVEEDLRSRGLAEVTSDEVGKAILKPLRDLDVVAYLRFASVYQNFAGLEDFQSAIDGLRE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=43.5374149659864, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17761; Mature: 17761

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFPPVHVILGSMHCPFCQNPDTKVIDTRISDDGHSIRRRRVCPKCNKRFTTVETSMLLV
CCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCHHHCCCHHHHHHHHEEE
TKRSGGVEPFSRDKVISGVRKACQGRPVREEDLKLLGQKVEEDLRSRGLAEVTSDEVGKA
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILKPLRDLDVVAYLRFASVYQNFAGLEDFQSAIDGLRE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVFPPVHVILGSMHCPFCQNPDTKVIDTRISDDGHSIRRRRVCPKCNKRFTTVETSMLLV
CCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCHHHCCCHHHHHHHHEEE
TKRSGGVEPFSRDKVISGVRKACQGRPVREEDLKLLGQKVEEDLRSRGLAEVTSDEVGKA
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILKPLRDLDVVAYLRFASVYQNFAGLEDFQSAIDGLRE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]