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The map label for this gene is glyQS [H]

Identifier: 213691693

GI number: 213691693

Start: 926312

End: 927784

Strand: Direct

Name: glyQS [H]

Synonym: Blon_0798

Alternate gene names: 213691693

Gene position: 926312-927784 (Clockwise)

Preceding gene: 213691690

Following gene: 213691694

Centisome position: 32.7

GC content: 62.93

Gene sequence:

>1473_bases
GTGGCTCAGTCCAAACTCGATGAAGTCGTATCCCTTGCGAAGCGTCGCGGCTTCGTGTTCCCCGCCGGCGAAATTTACGG
CGGCACCCGTTCCGCTTGGGATTACGGCCCCCTCGGCGTCGCTCTCAAGGACAATATCAAGCGTGAATGGTGGCGCTCCA
TGGTCGTCACCCGTCCTGATGTCGTCGGTGTCGACACCTCCATCATTCTGCCGCCCGAAGTGTGGGTGGCGTCCGGCCAC
GTGAGCGTGTTCAACGATCCGCTCGTCGAGTGCCTCAACTGCCACAAGCGCAACCGCGCCGACAAGCTCGAGGAATCCTA
CGCCGAGAAGCACGGCGACAAGATGCCGGAAAACGGCATGAAGGACATCGTCTGCCCGAACTGCGGCACCCGTGGACAGT
GGACCGAACCGCGCGACTTCAACATGATGCTGCGCACCCACCTCGGCCCGGTCGAGGACGAGAACAGCCTGCACTACCTG
CGTCCGGAGACTGCACAGGGCATCTTCGTCGACTTCAAGAACGTGATGACCTCCTCCCGTTCCAAGCCGCCGTTCGGCAT
CGCCAACATGGGTAAGTCCTTCCGTAACGAGATCACCCCGGGCAACTTCATCTTCCGCACCCGTGAGTTCGAGCAGATGG
AGATGGAGTTCTTCGTCACGCCCGGCACCGATGAGGAATGGCACCAGTACTGGATTGACGCCCGCACCCGCTGGTACATC
GACCTCGGCGTCAAGCCGGAGAACCTGCGCCACTACGAGCACCCGAAGGAGAAGCTCTCCCACTACTCCAAGCGCACAGT
GGACATCGAATACAAGTTCGGCTTCCAGGGTTCCGACTGGGGTGAGCTCGAAGGCATCGCCAACCGTACCGATTACGATT
TGAGCGCGCACTCCAAGCACTCCGGCGAAGACCTGAGCTACTTCAACCAGGCCACCGGCGAGAAGTACGTGCCGTACGTC
ATCGAACCGGCCGCCGGCCTGACCCGCTCCCTGATGTGCTTCCTCGTGGACGCCTACGATGTGGACGAGGCCCCGAACAC
CAAGGGCGGCGTCGACAAGCGCACCGTGCTGCGTCTCGACCCGCGTCTGGCCCCGGTCAAGGCCGCCGTGCTGCCGCTGA
GCAAGAAGCCTGAACTGCAGACCGTGGCCCAGAACCTGGCCGACGACCTGCGCTTCAACGAATGGATGATCGACTACGAC
GAGTCCGGTGCCATCGGCCGTCGTTACCGTCGTCAGGACGAGATCGGCACCCCGCTGTGCATCACCGTGGACTTCGACAC
CCTCGAGGACCACGCCGTGACCATCCGTGAGCGTGACACCATGGCCCAGGAGCGCGTCGCTCTTGACAAGGTGGCCGATT
ACGTGGCCGCCCGCATCGGCGAGAAGCGCACCCGCGTGCCCCTGAAGCCCGTGGAAATGGGCGGCGAGGCTTGGCCTGAG
TCCGGCGTTCAGGAAGCCGGCGGTCTGTACTAA

Upstream 100 bases:

>100_bases
GGAACATATACCGGACAATGCCGCCTGACCTGTCACCGTATACGGCTATCCTGAAGCGGTTGTTATTAGACCCCAAACCG
TTCAAACCAGAAGGTGCATT

Downstream 100 bases:

>100_bases
GCCGGAGTCGCACAACTTGGGCTCCCCTCTGTGGGCTGAGCCGTAAGGAAGACATCCCAGTGGGCTGTTTGTAGGCGAAG
TGGCGGCGATAGACGCCGGG

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MAQSKLDEVVSLAKRRGFVFPAGEIYGGTRSAWDYGPLGVALKDNIKREWWRSMVVTRPDVVGVDTSIILPPEVWVASGH
VSVFNDPLVECLNCHKRNRADKLEESYAEKHGDKMPENGMKDIVCPNCGTRGQWTEPRDFNMMLRTHLGPVEDENSLHYL
RPETAQGIFVDFKNVMTSSRSKPPFGIANMGKSFRNEITPGNFIFRTREFEQMEMEFFVTPGTDEEWHQYWIDARTRWYI
DLGVKPENLRHYEHPKEKLSHYSKRTVDIEYKFGFQGSDWGELEGIANRTDYDLSAHSKHSGEDLSYFNQATGEKYVPYV
IEPAAGLTRSLMCFLVDAYDVDEAPNTKGGVDKRTVLRLDPRLAPVKAAVLPLSKKPELQTVAQNLADDLRFNEWMIDYD
ESGAIGRRYRRQDEIGTPLCITVDFDTLEDHAVTIRERDTMAQERVALDKVADYVAARIGEKRTRVPLKPVEMGGEAWPE
SGVQEAGGLY

Sequences:

>Translated_490_residues
MAQSKLDEVVSLAKRRGFVFPAGEIYGGTRSAWDYGPLGVALKDNIKREWWRSMVVTRPDVVGVDTSIILPPEVWVASGH
VSVFNDPLVECLNCHKRNRADKLEESYAEKHGDKMPENGMKDIVCPNCGTRGQWTEPRDFNMMLRTHLGPVEDENSLHYL
RPETAQGIFVDFKNVMTSSRSKPPFGIANMGKSFRNEITPGNFIFRTREFEQMEMEFFVTPGTDEEWHQYWIDARTRWYI
DLGVKPENLRHYEHPKEKLSHYSKRTVDIEYKFGFQGSDWGELEGIANRTDYDLSAHSKHSGEDLSYFNQATGEKYVPYV
IEPAAGLTRSLMCFLVDAYDVDEAPNTKGGVDKRTVLRLDPRLAPVKAAVLPLSKKPELQTVAQNLADDLRFNEWMIDYD
ESGAIGRRYRRQDEIGTPLCITVDFDTLEDHAVTIRERDTMAQERVALDKVADYVAARIGEKRTRVPLKPVEMGGEAWPE
SGVQEAGGLY
>Mature_489_residues
AQSKLDEVVSLAKRRGFVFPAGEIYGGTRSAWDYGPLGVALKDNIKREWWRSMVVTRPDVVGVDTSIILPPEVWVASGHV
SVFNDPLVECLNCHKRNRADKLEESYAEKHGDKMPENGMKDIVCPNCGTRGQWTEPRDFNMMLRTHLGPVEDENSLHYLR
PETAQGIFVDFKNVMTSSRSKPPFGIANMGKSFRNEITPGNFIFRTREFEQMEMEFFVTPGTDEEWHQYWIDARTRWYID
LGVKPENLRHYEHPKEKLSHYSKRTVDIEYKFGFQGSDWGELEGIANRTDYDLSAHSKHSGEDLSYFNQATGEKYVPYVI
EPAAGLTRSLMCFLVDAYDVDEAPNTKGGVDKRTVLRLDPRLAPVKAAVLPLSKKPELQTVAQNLADDLRFNEWMIDYDE
SGAIGRRYRRQDEIGTPLCITVDFDTLEDHAVTIRERDTMAQERVALDKVADYVAARIGEKRTRVPLKPVEMGGEAWPES
GVQEAGGLY

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=354, Percent_Identity=30.7909604519774, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI70887790, Length=442, Percent_Identity=24.6606334841629, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564541, Length=360, Percent_Identity=29.7222222222222, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17554996, Length=373, Percent_Identity=29.4906166219839, Blast_Score=141, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6325338, Length=374, Percent_Identity=27.807486631016, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319597, Length=247, Percent_Identity=31.9838056680162, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357965, Length=357, Percent_Identity=30.812324929972, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24664462, Length=357, Percent_Identity=30.812324929972, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 55844; Mature: 55712

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50862 AA_TRNA_LIGASE_II ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSKLDEVVSLAKRRGFVFPAGEIYGGTRSAWDYGPLGVALKDNIKREWWRSMVVTRPD
CCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
VVGVDTSIILPPEVWVASGHVSVFNDPLVECLNCHKRNRADKLEESYAEKHGDKMPENGM
EECCCCEEEECCCEEEECCCCEECCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
KDIVCPNCGTRGQWTEPRDFNMMLRTHLGPVEDENSLHYLRPETAQGIFVDFKNVMTSSR
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEHHHHHHCCC
SKPPFGIANMGKSFRNEITPGNFIFRTREFEQMEMEFFVTPGTDEEWHQYWIDARTRWYI
CCCCCCHHHHCHHHHHCCCCCCEEEECCCHHCEEEEEEEECCCCHHHHHHHHCCCEEEEE
DLGVKPENLRHYEHPKEKLSHYSKRTVDIEYKFGFQGSDWGELEGIANRTDYDLSAHSKH
EECCCHHHCHHHCCHHHHHHHHHCCEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCC
SGEDLSYFNQATGEKYVPYVIEPAAGLTRSLMCFLVDAYDVDEAPNTKGGVDKRTVLRLD
CCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
PRLAPVKAAVLPLSKKPELQTVAQNLADDLRFNEWMIDYDESGAIGRRYRRQDEIGTPLC
CCCCCCHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEE
ITVDFDTLEDHAVTIRERDTMAQERVALDKVADYVAARIGEKRTRVPLKPVEMGGEAWPE
EEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHCCCCCCCC
SGVQEAGGLY
CCHHHCCCCC
>Mature Secondary Structure 
AQSKLDEVVSLAKRRGFVFPAGEIYGGTRSAWDYGPLGVALKDNIKREWWRSMVVTRPD
CHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
VVGVDTSIILPPEVWVASGHVSVFNDPLVECLNCHKRNRADKLEESYAEKHGDKMPENGM
EECCCCEEEECCCEEEECCCCEECCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
KDIVCPNCGTRGQWTEPRDFNMMLRTHLGPVEDENSLHYLRPETAQGIFVDFKNVMTSSR
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEHHHHHHCCC
SKPPFGIANMGKSFRNEITPGNFIFRTREFEQMEMEFFVTPGTDEEWHQYWIDARTRWYI
CCCCCCHHHHCHHHHHCCCCCCEEEECCCHHCEEEEEEEECCCCHHHHHHHHCCCEEEEE
DLGVKPENLRHYEHPKEKLSHYSKRTVDIEYKFGFQGSDWGELEGIANRTDYDLSAHSKH
EECCCHHHCHHHCCHHHHHHHHHCCEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCC
SGEDLSYFNQATGEKYVPYVIEPAAGLTRSLMCFLVDAYDVDEAPNTKGGVDKRTVLRLD
CCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
PRLAPVKAAVLPLSKKPELQTVAQNLADDLRFNEWMIDYDESGAIGRRYRRQDEIGTPLC
CCCCCCHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEE
ITVDFDTLEDHAVTIRERDTMAQERVALDKVADYVAARIGEKRTRVPLKPVEMGGEAWPE
EEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHCCCCCCCC
SGVQEAGGLY
CCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]