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The map label for this gene is degU [H]

Identifier: 213691377

GI number: 213691377

Start: 541791

End: 542534

Strand: Reverse

Name: degU [H]

Synonym: Blon_0471

Alternate gene names: 213691377

Gene position: 542534-541791 (Counterclockwise)

Preceding gene: 213691378

Following gene: 213691376

Centisome position: 19.15

GC content: 59.54

Gene sequence:

>744_bases
ATGACGAACATCATGCTGGTCGATGACCTGCAATACGCGAGGCTCGGCTACAAACTCATGCTTGGCAAGGCGAGTGACAT
CGCGATCGTCGCTCAGGCGGGCGATGGCCGACAGGCTATCGCTGAAATCGAGCGACTGGAATCGGCAGGAGGCCCGCTGC
CGGACGTGGTGCTCATGGACGTGCGCATGCCCGTGATGGACGGCATCACCGCCACCCGTGAAATCACCCGCCGATGGCCC
GCCATTCACGTGCTGATCCTCACCACGTACGACGAGGACGACTACGCATACGGTGGACTGGATGCGGGAGCCAGCGGATT
CCTGCTCAAAGACGCCAGTGCTGCAGCCGTCAAGGATGCGATTCATGCGGTGGCGAACGGAGACGCCGTGGTCACGCCAC
GCATCACCCGGCAGATTCTCGAACACGGCATGCCCAGACCCACAGCAGGCCGCGAACAACAGAAGCTGCGGGATTCGTTC
GCAGCCCTGCCGCCGCGCCAACGCGAGATATGCACACTGATCGCGGAAGGCATGACCAACGAGGAAATCGCCCGCAAACT
GGTACTGGAGCCCGCGACGATACGACGAACCATCAGTCGAATCCTCTTCACCTTGCAACTGCATGACCGCACGCAAATCG
CCGTCAGCTGGCTCAAGTCCCACGCATCACAGCAAGCAATGTCAATGGTAAGAACACGAAGATATGTGTCATCTTCAGCT
GACAATCCGCTCCAAACACATTGA

Upstream 100 bases:

>100_bases
GAAGGGTTCCTCTGCTACGGGCCGGACAGGGCGGAAACCGGTGTCTGGCGGGTGACCGCGATGCTGACGTCCGTCCGACA
AGAGAAAGGCGTGACGTGGG

Downstream 100 bases:

>100_bases
AATCAATAAGTAAGGATACAACAATGAAAAATTATTAAAGCATACAAGAAAAAAGGAAAAATATGATTGGTGAAGAAGAT
TACCTCGAATCAATTACGAA

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTNIMLVDDLQYARLGYKLMLGKASDIAIVAQAGDGRQAIAEIERLESAGGPLPDVVLMDVRMPVMDGITATREITRRWP
AIHVLILTTYDEDDYAYGGLDAGASGFLLKDASAAAVKDAIHAVANGDAVVTPRITRQILEHGMPRPTAGREQQKLRDSF
AALPPRQREICTLIAEGMTNEEIARKLVLEPATIRRTISRILFTLQLHDRTQIAVSWLKSHASQQAMSMVRTRRYVSSSA
DNPLQTH

Sequences:

>Translated_247_residues
MTNIMLVDDLQYARLGYKLMLGKASDIAIVAQAGDGRQAIAEIERLESAGGPLPDVVLMDVRMPVMDGITATREITRRWP
AIHVLILTTYDEDDYAYGGLDAGASGFLLKDASAAAVKDAIHAVANGDAVVTPRITRQILEHGMPRPTAGREQQKLRDSF
AALPPRQREICTLIAEGMTNEEIARKLVLEPATIRRTISRILFTLQLHDRTQIAVSWLKSHASQQAMSMVRTRRYVSSSA
DNPLQTH
>Mature_246_residues
TNIMLVDDLQYARLGYKLMLGKASDIAIVAQAGDGRQAIAEIERLESAGGPLPDVVLMDVRMPVMDGITATREITRRWPA
IHVLILTTYDEDDYAYGGLDAGASGFLLKDASAAAVKDAIHAVANGDAVVTPRITRQILEHGMPRPTAGREQQKLRDSFA
ALPPRQREICTLIAEGMTNEEIARKLVLEPATIRRTISRILFTLQLHDRTQIAVSWLKSHASQQAMSMVRTRRYVSSSAD
NPLQTH

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=221, Percent_Identity=29.8642533936652, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=30.0469483568075, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790102, Length=214, Percent_Identity=27.1028037383178, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787473, Length=217, Percent_Identity=29.4930875576037, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=25.9803921568627, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=25.1207729468599, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27214; Mature: 27083

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIMLVDDLQYARLGYKLMLGKASDIAIVAQAGDGRQAIAEIERLESAGGPLPDVVLMD
CCCEEEECCCHHHHHCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEE
VRMPVMDGITATREITRRWPAIHVLILTTYDEDDYAYGGLDAGASGFLLKDASAAAVKDA
CCHHHHHCHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHH
IHAVANGDAVVTPRITRQILEHGMPRPTAGREQQKLRDSFAALPPRQREICTLIAEGMTN
HHHHCCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
EEIARKLVLEPATIRRTISRILFTLQLHDRTQIAVSWLKSHASQQAMSMVRTRRYVSSSA
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNPLQTH
CCCCCCC
>Mature Secondary Structure 
TNIMLVDDLQYARLGYKLMLGKASDIAIVAQAGDGRQAIAEIERLESAGGPLPDVVLMD
CCEEEECCCHHHHHCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEE
VRMPVMDGITATREITRRWPAIHVLILTTYDEDDYAYGGLDAGASGFLLKDASAAAVKDA
CCHHHHHCHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHH
IHAVANGDAVVTPRITRQILEHGMPRPTAGREQQKLRDSFAALPPRQREICTLIAEGMTN
HHHHCCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
EEIARKLVLEPATIRRTISRILFTLQLHDRTQIAVSWLKSHASQQAMSMVRTRRYVSSSA
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNPLQTH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]