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The map label for this gene is rnc [H]

Identifier: 213691313

GI number: 213691313

Start: 462723

End: 463451

Strand: Reverse

Name: rnc [H]

Synonym: Blon_0400

Alternate gene names: 213691313

Gene position: 463451-462723 (Counterclockwise)

Preceding gene: 213691314

Following gene: 213691312

Centisome position: 16.36

GC content: 62.28

Gene sequence:

>729_bases
ATGAGTAATGAAACCCCACAGCAGCCGACGCCGGCCAACGAGCTTCTTGAAGCGTTGGGCACCACTCTTAGCCCGGATCT
GCTCGTGCAGGCACTCACCCACCGCTCCTTCTCGCATGAGCACCCCGGCGTGGCCAATTACGAACGCCTCGAATTCCTGG
GAGACGCGGTGCTCGAACTGGTCTCCACTGAAACGCTGTTCACTATTCACCCGGATATGACCGAGGGGCAACTGGCCAAG
ATGCGCGCCAAGGCCGTCTCCGAAGACGCGCTGAGTGCCATCGCCAAAACCAAGCTCAAGGTGGGCCCCTACATTCTGCT
GGGTCACGGGGAAGCCGAGCAGGGCGGCGCGGAGAAGAACTCCATTCTGTGCGACATCGTGGAATCGCTCATCGGCGCGA
CTTTCCTGGAACACGGCATCGACGAGGCACGCAAGGTGCTTCACCGGCTTATTGACGACACGCTCGCCGAAGTGGCCACC
GAGGGCCCGGCACTCGACTGGAAGACCTCGCTGACCGTCAAGGCGCACGGCCTCGGCAAGGAGGAGCCTGTCTACCATAT
GGAGGTCTCCGGCCCGGAATACGCGCAGATCTTCACCGCGCGCGTCTCGTTGGGCGAGAACGGCGACATCATCGGCATCG
GTAAGGGCTCCAGCAAGCGTAAGGCGCAGCTGGCGGCCGCCGAAGCGGGCTGGAAGTCACTGGACTCGCTCAAGACGCGG
ACTAAGTAA

Upstream 100 bases:

>100_bases
GGGGCCTTCGCATAAGTGCACCATTACGTACACCATCGCATCGCACACAACACAACACAACACAACACATCACCATCGCG
TGAAGGACCATACAACAATC

Downstream 100 bases:

>100_bases
GCCCGCTGTCGGATTTGCGAATAGACTGATACCAACATGAGCGACGAGTCGTGTCGGGGCCACAAGTCTCGGGGAAGCGA
CTGGAATCAGACACGCGGGC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSNETPQQPTPANELLEALGTTLSPDLLVQALTHRSFSHEHPGVANYERLEFLGDAVLELVSTETLFTIHPDMTEGQLAK
MRAKAVSEDALSAIAKTKLKVGPYILLGHGEAEQGGAEKNSILCDIVESLIGATFLEHGIDEARKVLHRLIDDTLAEVAT
EGPALDWKTSLTVKAHGLGKEEPVYHMEVSGPEYAQIFTARVSLGENGDIIGIGKGSSKRKAQLAAAEAGWKSLDSLKTR
TK

Sequences:

>Translated_242_residues
MSNETPQQPTPANELLEALGTTLSPDLLVQALTHRSFSHEHPGVANYERLEFLGDAVLELVSTETLFTIHPDMTEGQLAK
MRAKAVSEDALSAIAKTKLKVGPYILLGHGEAEQGGAEKNSILCDIVESLIGATFLEHGIDEARKVLHRLIDDTLAEVAT
EGPALDWKTSLTVKAHGLGKEEPVYHMEVSGPEYAQIFTARVSLGENGDIIGIGKGSSKRKAQLAAAEAGWKSLDSLKTR
TK
>Mature_241_residues
SNETPQQPTPANELLEALGTTLSPDLLVQALTHRSFSHEHPGVANYERLEFLGDAVLELVSTETLFTIHPDMTEGQLAKM
RAKAVSEDALSAIAKTKLKVGPYILLGHGEAEQGGAEKNSILCDIVESLIGATFLEHGIDEARKVLHRLIDDTLAEVATE
GPALDWKTSLTVKAHGLGKEEPVYHMEVSGPEYAQIFTARVSLGENGDIIGIGKGSSKRKAQLAAAEAGWKSLDSLKTRT
K

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=221, Percent_Identity=28.0542986425339, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI155030234, Length=221, Percent_Identity=28.0542986425339, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1788920, Length=229, Percent_Identity=36.6812227074236, Blast_Score=109, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17137682, Length=209, Percent_Identity=25.3588516746411, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 26046; Mature: 25915

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETPQQPTPANELLEALGTTLSPDLLVQALTHRSFSHEHPGVANYERLEFLGDAVLEL
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VSTETLFTIHPDMTEGQLAKMRAKAVSEDALSAIAKTKLKVGPYILLGHGEAEQGGAEKN
HCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCH
SILCDIVESLIGATFLEHGIDEARKVLHRLIDDTLAEVATEGPALDWKTSLTVKAHGLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EEPVYHMEVSGPEYAQIFTARVSLGENGDIIGIGKGSSKRKAQLAAAEAGWKSLDSLKTR
CCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
TK
CC
>Mature Secondary Structure 
SNETPQQPTPANELLEALGTTLSPDLLVQALTHRSFSHEHPGVANYERLEFLGDAVLEL
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VSTETLFTIHPDMTEGQLAKMRAKAVSEDALSAIAKTKLKVGPYILLGHGEAEQGGAEKN
HCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCH
SILCDIVESLIGATFLEHGIDEARKVLHRLIDDTLAEVATEGPALDWKTSLTVKAHGLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EEPVYHMEVSGPEYAQIFTARVSLGENGDIIGIGKGSSKRKAQLAAAEAGWKSLDSLKTR
CCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]