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The map label for this gene is pepC [H]

Identifier: 213691272

GI number: 213691272

Start: 412699

End: 414042

Strand: Direct

Name: pepC [H]

Synonym: Blon_0356

Alternate gene names: 213691272

Gene position: 412699-414042 (Clockwise)

Preceding gene: 213691271

Following gene: 213691273

Centisome position: 14.57

GC content: 62.05

Gene sequence:

>1344_bases
ATGAGTGAATTGACGCCTCTGACCGGCGAAGCATTGAATACCCTGCGCGGCGATTTCGCACAGAGTGGCACCAACCGTCT
GGCCATGAACGCGGTGACCGCCGCCGGCATCGACAAGGTGGCTCGCAATTATGACCGCGCTCGTCTGATGCAGCGCCGTT
TCTCCACCATCGTTGACAATGGCGAAGCCACCCATCAGGATCGCTCCGGCCGCTGCTGGCTGTTCAGCTCCCTGAACGTG
GCCCGTTTCGTGGCCAAGAAGAACATGAACTTGAAGGAGTTCGAGTTCTCCCAGAACTACGCGATGTACTACGACAAGCT
GGAGCGCGTCAACTACTTCCTTAAGGATGTGGCCGCTCTGGTGGCTGCCGGGGAGCCGTCCGACTCCCGCCTGATGCAGC
ACCTGCTCGCCGACGTGATGGGCGATGGCGGCCAGTGGACCATGGCCATGAACGTGTACAAGAAGTACGGCGCTGTGCCC
AAGGACCTGTTCCCGGAGACCGAATCCTCCAAGAACACCGGTGAGATGAACACCCAGCTGCGCCACATGCTGCACACCGC
CGTGGCGCACATGTACGCCGCTGACGGCGATGCCTCCAAGGTCGAGGCGATTATTGCCGACGCCACTGCTGCCGGCCACC
GTATTCTGACCATCCACCTGGGCGAGCCGCCGGTCTCCTTCGACTGGGAATGGACCGACAAGGATGGCGAATTCCACCGC
GACGGCGAGATCACGCCGGTCGAATTCTGGAAGAAGTACGTGGGACCGGCCGGTCTCGAGGACTACGTGTGCCTGGTGGA
TGATCCGCGCACCGAGCACGCCAAGGGCAAGAAGATCGGCATCGAGCACCTCGGCAATGTGGCTGGCGGCGACGCCACCG
AGTACCTCAACGTGCCAAACCAGTTCATGAAGGACTGTGTCAAGCAGATTCTCGTTGAGCAGGGCATCCCGGTATGGTTC
GGTGCCGACTGCCACCCGTTCATGGACCGTGAGAACGGCGCTTGGGCCACCGACCTGTTCGAGTACGGCCGCGTGTACGA
CGTGGACTTCGATTTGGACAAGGAAGCCCGCGTGCGCTTCGGTGACTCCGCCATGAACCACGCCATGGCCTTCGCCGGCG
TGGACGTCGCCGATGACGGCTCCACGCGGCGCTGGCGTGTGGAGAACTCCTGGGGTGCCAAGATCGCCGACAAGGGCTAC
TTCACCATGTCCGACGACTGGTTCACCGAATACGTCTACGAGGTCGCCGTCCCCAAGGCCATGCTTCCCGAAGAGTACCG
CAAGGCCTTGGAATCCCCGGCCACCATGCTCCCCGCATGGGATCCGATGGGCGCGCTCGCATAA

Upstream 100 bases:

>100_bases
GACTACTAGCGGTAAGAATTACGGCACCTGCGCTTTCGAGCCAGGTGCCGTATTCGTTTGGATCTGCGCCGCAAGCGCAC
CATCACAGAAGGAGTATGAC

Downstream 100 bases:

>100_bases
GAGGGCGTATGGGCTTGACGGGTGGGCGCCGCCCGTCAAGCCCGGCGCCGCCGCAGACGGTCCATAATCGCCGGCCCCGC
CAGCGGTGCCGGCGGCGAAC

Product: Bleomycin hydrolase

Products: NA

Alternate protein names: Bleomycin hydrolase [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSELTPLTGEALNTLRGDFAQSGTNRLAMNAVTAAGIDKVARNYDRARLMQRRFSTIVDNGEATHQDRSGRCWLFSSLNV
ARFVAKKNMNLKEFEFSQNYAMYYDKLERVNYFLKDVAALVAAGEPSDSRLMQHLLADVMGDGGQWTMAMNVYKKYGAVP
KDLFPETESSKNTGEMNTQLRHMLHTAVAHMYAADGDASKVEAIIADATAAGHRILTIHLGEPPVSFDWEWTDKDGEFHR
DGEITPVEFWKKYVGPAGLEDYVCLVDDPRTEHAKGKKIGIEHLGNVAGGDATEYLNVPNQFMKDCVKQILVEQGIPVWF
GADCHPFMDRENGAWATDLFEYGRVYDVDFDLDKEARVRFGDSAMNHAMAFAGVDVADDGSTRRWRVENSWGAKIADKGY
FTMSDDWFTEYVYEVAVPKAMLPEEYRKALESPATMLPAWDPMGALA

Sequences:

>Translated_447_residues
MSELTPLTGEALNTLRGDFAQSGTNRLAMNAVTAAGIDKVARNYDRARLMQRRFSTIVDNGEATHQDRSGRCWLFSSLNV
ARFVAKKNMNLKEFEFSQNYAMYYDKLERVNYFLKDVAALVAAGEPSDSRLMQHLLADVMGDGGQWTMAMNVYKKYGAVP
KDLFPETESSKNTGEMNTQLRHMLHTAVAHMYAADGDASKVEAIIADATAAGHRILTIHLGEPPVSFDWEWTDKDGEFHR
DGEITPVEFWKKYVGPAGLEDYVCLVDDPRTEHAKGKKIGIEHLGNVAGGDATEYLNVPNQFMKDCVKQILVEQGIPVWF
GADCHPFMDRENGAWATDLFEYGRVYDVDFDLDKEARVRFGDSAMNHAMAFAGVDVADDGSTRRWRVENSWGAKIADKGY
FTMSDDWFTEYVYEVAVPKAMLPEEYRKALESPATMLPAWDPMGALA
>Mature_446_residues
SELTPLTGEALNTLRGDFAQSGTNRLAMNAVTAAGIDKVARNYDRARLMQRRFSTIVDNGEATHQDRSGRCWLFSSLNVA
RFVAKKNMNLKEFEFSQNYAMYYDKLERVNYFLKDVAALVAAGEPSDSRLMQHLLADVMGDGGQWTMAMNVYKKYGAVPK
DLFPETESSKNTGEMNTQLRHMLHTAVAHMYAADGDASKVEAIIADATAAGHRILTIHLGEPPVSFDWEWTDKDGEFHRD
GEITPVEFWKKYVGPAGLEDYVCLVDDPRTEHAKGKKIGIEHLGNVAGGDATEYLNVPNQFMKDCVKQILVEQGIPVWFG
ADCHPFMDRENGAWATDLFEYGRVYDVDFDLDKEARVRFGDSAMNHAMAFAGVDVADDGSTRRWRVENSWGAKIADKGYF
TMSDDWFTEYVYEVAVPKAMLPEEYRKALESPATMLPAWDPMGALA

Specific function: Unknown

COG id: COG3579

COG function: function code E; Aminopeptidase C

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C1 family [H]

Homologues:

Organism=Homo sapiens, GI4557367, Length=394, Percent_Identity=41.6243654822335, Blast_Score=324, Evalue=8e-89,
Organism=Saccharomyces cerevisiae, GI6324090, Length=455, Percent_Identity=36.2637362637363, Blast_Score=265, Evalue=8e-72,
Organism=Drosophila melanogaster, GI161077632, Length=455, Percent_Identity=35.3846153846154, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24640588, Length=455, Percent_Identity=35.3846153846154, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI161077630, Length=367, Percent_Identity=37.3297002724796, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI20130175, Length=464, Percent_Identity=26.5086206896552, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000169
- InterPro:   IPR004134 [H]

Pfam domain/function: PF03051 Peptidase_C1_2 [H]

EC number: =3.4.22.40 [H]

Molecular weight: Translated: 50134; Mature: 50003

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00139 THIOL_PROTEASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELTPLTGEALNTLRGDFAQSGTNRLAMNAVTAAGIDKVARNYDRARLMQRRFSTIVDN
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEATHQDRSGRCWLFSSLNVARFVAKKNMNLKEFEFSQNYAMYYDKLERVNYFLKDVAAL
CCCCCCCCCCCEEEEECCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
VAAGEPSDSRLMQHLLADVMGDGGQWTMAMNVYKKYGAVPKDLFPETESSKNTGEMNTQL
HHCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHH
RHMLHTAVAHMYAADGDASKVEAIIADATAAGHRILTIHLGEPPVSFDWEWTDKDGEFHR
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCC
DGEITPVEFWKKYVGPAGLEDYVCLVDDPRTEHAKGKKIGIEHLGNVAGGDATEYLNVPN
CCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEECHHHHCCCCCCCHHHHHCCCH
QFMKDCVKQILVEQGIPVWFGADCHPFMDRENGAWATDLFEYGRVYDVDFDLDKEARVRF
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCHHHEEE
GDSAMNHAMAFAGVDVADDGSTRRWRVENSWGAKIADKGYFTMSDDWFTEYVYEVAVPKA
CCHHHHHHHHHCCCEECCCCCCCEEEECCCCCCEEECCCCEEECCHHHHHHHHHHHCCHH
MLPEEYRKALESPATMLPAWDPMGALA
CCCHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SELTPLTGEALNTLRGDFAQSGTNRLAMNAVTAAGIDKVARNYDRARLMQRRFSTIVDN
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEATHQDRSGRCWLFSSLNVARFVAKKNMNLKEFEFSQNYAMYYDKLERVNYFLKDVAAL
CCCCCCCCCCCEEEEECCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
VAAGEPSDSRLMQHLLADVMGDGGQWTMAMNVYKKYGAVPKDLFPETESSKNTGEMNTQL
HHCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHH
RHMLHTAVAHMYAADGDASKVEAIIADATAAGHRILTIHLGEPPVSFDWEWTDKDGEFHR
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCC
DGEITPVEFWKKYVGPAGLEDYVCLVDDPRTEHAKGKKIGIEHLGNVAGGDATEYLNVPN
CCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEECHHHHCCCCCCCHHHHHCCCH
QFMKDCVKQILVEQGIPVWFGADCHPFMDRENGAWATDLFEYGRVYDVDFDLDKEARVRF
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCHHHEEE
GDSAMNHAMAFAGVDVADDGSTRRWRVENSWGAKIADKGYFTMSDDWFTEYVYEVAVPKA
CCHHHHHHHHHCCCEECCCCCCCEEEECCCCCCEEECCCCEEECCHHHHHHHHHHHCCHH
MLPEEYRKALESPATMLPAWDPMGALA
CCCHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7851736 [H]