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The map label for this gene is pcp [H]

Identifier: 213691270

GI number: 213691270

Start: 410200

End: 410877

Strand: Direct

Name: pcp [H]

Synonym: Blon_0354

Alternate gene names: 213691270

Gene position: 410200-410877 (Clockwise)

Preceding gene: 213691269

Following gene: 213691271

Centisome position: 14.48

GC content: 61.8

Gene sequence:

>678_bases
ATGCGTGAACTCAATGTTGTGATCTCCGGCTTCGACCACTATGACGGCGTGGAGGTCAATCCCGCCGTCGAAGTGCCCAA
GGCCATCGCCGAGCAGGGACTGGGCGTCTCCTCTGCTCCGGACGATCCGTTGGAGCAGGTCGCCGTCACCGTTCATGCCG
TCAGCATCCCGGTGAGCTTCGCCAAAGCCTGGCCCACGCTGAAAGAGACCATTGAGGCCACCAAGCCCAATATCGTCATC
GCCACCGGGCTCAAGCACGCAGCCCGAGGCGTGATGCTTGAACGATGCGCCACCAACCTGATGGACGCGATCAGGCCGGA
CGCGGACAACGTGACCCCACGCCGCGAACCCATCGACCCCAATGGCCCGGCCGCCTATTGGACCCGCCTGCCGTTGCGCT
CGATCCTGAATGATTTCACGGATGATTCTATTCCGGCCACCCTGAGTTCGGACGCAGGTACGTTCGTATGTAATTCGCTG
TTCTACAACTTGCTCAACTGGACCGCCACCCAGGAGCGGGTGCTGGGCGGATTCGTCAGCTTCCCTCCGGTCGTTCCGGC
GCATTCCAGCCAGCATGGTCTACCACTCGACCAGCAGATCGCCGCTGGCCGTGATGTGGTGCGCGAAGCCGTACGCTACT
ATCTCAAGCCCTCCAGCTCCGACATCCTCATCGCCTAG

Upstream 100 bases:

>100_bases
CGAGGAGATTCTCGGTCGTGATCCCAAGGAAGAGGCCCGCGCCCGCATGCATGCCCTGCTGGCCCAAGCAGCCGGCCAGA
TGCATCGCTAGACTGGCATT

Downstream 100 bases:

>100_bases
CACGCTGTGCGCCACGCCGGAATAGAACATGGTTCGCACGCATTGTAACGATTGCGCGTCGCTCAACGCTCAGCGCTAGT
GCGATGCGCTACAGTGCTTC

Product: Pyroglutamyl-peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRELNVVISGFDHYDGVEVNPAVEVPKAIAEQGLGVSSAPDDPLEQVAVTVHAVSIPVSFAKAWPTLKETIEATKPNIVI
ATGLKHAARGVMLERCATNLMDAIRPDADNVTPRREPIDPNGPAAYWTRLPLRSILNDFTDDSIPATLSSDAGTFVCNSL
FYNLLNWTATQERVLGGFVSFPPVVPAHSSQHGLPLDQQIAAGRDVVREAVRYYLKPSSSDILIA

Sequences:

>Translated_225_residues
MRELNVVISGFDHYDGVEVNPAVEVPKAIAEQGLGVSSAPDDPLEQVAVTVHAVSIPVSFAKAWPTLKETIEATKPNIVI
ATGLKHAARGVMLERCATNLMDAIRPDADNVTPRREPIDPNGPAAYWTRLPLRSILNDFTDDSIPATLSSDAGTFVCNSL
FYNLLNWTATQERVLGGFVSFPPVVPAHSSQHGLPLDQQIAAGRDVVREAVRYYLKPSSSDILIA
>Mature_225_residues
MRELNVVISGFDHYDGVEVNPAVEVPKAIAEQGLGVSSAPDDPLEQVAVTVHAVSIPVSFAKAWPTLKETIEATKPNIVI
ATGLKHAARGVMLERCATNLMDAIRPDADNVTPRREPIDPNGPAAYWTRLPLRSILNDFTDDSIPATLSSDAGTFVCNSL
FYNLLNWTATQERVLGGFVSFPPVVPAHSSQHGLPLDQQIAAGRDVVREAVRYYLKPSSSDILIA

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 24324; Mature: 24324

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01334 PYRASE_CYS ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELNVVISGFDHYDGVEVNPAVEVPKAIAEQGLGVSSAPDDPLEQVAVTVHAVSIPVSF
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AKAWPTLKETIEATKPNIVIATGLKHAARGVMLERCATNLMDAIRPDADNVTPRREPIDP
HHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NGPAAYWTRLPLRSILNDFTDDSIPATLSSDAGTFVCNSLFYNLLNWTATQERVLGGFVS
CCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHC
FPPVVPAHSSQHGLPLDQQIAAGRDVVREAVRYYLKPSSSDILIA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure
MRELNVVISGFDHYDGVEVNPAVEVPKAIAEQGLGVSSAPDDPLEQVAVTVHAVSIPVSF
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AKAWPTLKETIEATKPNIVIATGLKHAARGVMLERCATNLMDAIRPDADNVTPRREPIDP
HHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NGPAAYWTRLPLRSILNDFTDDSIPATLSSDAGTFVCNSLFYNLLNWTATQERVLGGFVS
CCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHC
FPPVVPAHSSQHGLPLDQQIAAGRDVVREAVRYYLKPSSSDILIA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1353026; 7704254; 9384377; 1362573 [H]