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The map label for this gene is zwf [H]

Identifier: 213691131

GI number: 213691131

Start: 254004

End: 255542

Strand: Reverse

Name: zwf [H]

Synonym: Blon_0210

Alternate gene names: 213691131

Gene position: 255542-254004 (Counterclockwise)

Preceding gene: 213691133

Following gene: 213691130

Centisome position: 9.02

GC content: 63.94

Gene sequence:

>1539_bases
ATGAGTGAATCCCCCAACTGGAGCAATCCACTGCGCGACTCGCGCGATCTCAGACTGCCCCGCATCGCCGGCCCGTGCAG
CCTTGTCATTTTCGGCGTCACGGGTGACTTGGCGCAGAAGAAACTGCTGCCGGCCGTCTACGACCTGGCGAACCGTGGCC
TGCTGCCGCCGAGCTTCGGTCTGACCGGCTTCGCCCGCCGAGACTGGACACAGGAACGGTTCATCGAATTCGTCAAGGCC
GCTATCCAGGCGCATTGCCGTACGCCGTTCAAGGAGTCGACTTGGCGCAATCTGGCCGCCGGAATCCGCTTCGTTCAGGG
TACGTTCGACGATCAGGAGGCGTTCGAGCGTCTGAGCGCCACCGTGCAGGAGCTTGACCGCGATCGTGGCACGCAGGGTA
ACCATGCCTTCTACATGTCGGTGCCGCCGCGGGCTTTCCCGCAGGTTGCCAAGCAGCTGGCCGCCTCCGGCCTGTCGCGC
TCGTCCGAGGGAGCGTGGCGCCGCGTGATCATCGAGAAGCCGTTCGGCCATGATCTGGCCAGCGCCAAGGAACTCGACAG
CGTGGTGTCCGAGGTGTTCGACCCGAGTTCCGTGTTCCGCATCGACCACTACCTCGGCAAGGAGACCGTGCAGAACCTGC
TGGCCCTGCGCTTCGCCAACGCCATGTACGAGCCGATCTGGAACGCCAACTACGTGGATCATGTGCAGATCACGATGGCC
GAGGACATCGGCATCGGAGGACGCGCCGGATATTATGACGGCATCGGCGCGGCGCGCGACGTGATCCAGAACCACCTGCT
GCAGCTCATGGCCCTGACCGCCATGGAGGAGCCGGTGAGCTTCACCGCCAAGGATCTGACCGCCGAGAAGACCAAGGTGC
TTTCCGCCGTGCGTCTACCCAAGGATCTTGCCGCCAACACCGCGCGCGGCCAGTACGCCAAGGGCTGGCAGGGCTCGCAC
GAAGTGGTCGGCTACTTGGAAGAAAAAGGCATCGACCCCAAGAGCACCACTGAAACGTACGCCGCCATCCGCCTTGACAT
CGACACCCGCCGCTGGGCCGGCGTGCCGTTCTACCTGCGTTGCGGCAAGCGTCTGGGTAAGCGTGTCACCGAGATCGCCG
TGATGTTCAAACGCGCCCCGCACCTGCCGTTCGAACAGACCGCCGTGCGCGAACTCGGCAAGAACGCCATCGTGATTCGC
GTTCAGCCCGACGAGGGCGTCACCATGCGTTTCGGCGCCAAGGTGCCGGGCGGCTCCACCATGGAGGTCCGAGACGTGAA
CATGGACTTCAGCTATGGTCGCTCCTTCACCGAGAACTCGCCGGAAGCCTACGAACGACTGATTCTGGACGTGCTGCTCG
GCGACCCGCCGCTGTTCCCCACCACCGAAGAGGTGAACCTCAGCTGGGAGATTCTCGACCCGATTGAACGATTCTGGTCC
ACGCTCGGCCAGCCGCAAGCCTATCGCTCCGGCACATGGGGCCCAACCCAAGCCGACGACATGCTGGCACGCGACGGACG
CCATTGGAGGATGCCATGA

Upstream 100 bases:

>100_bases
CGCGACGACCGTCGGCCCGTCCGCGCGTATGGCCCATATCACGCCCACATCGCACGCGCCCTCTGGCCATGCACGGCCAT
GAACGACTACCCTTGGCCAT

Downstream 100 bases:

>100_bases
TCATCGACATGCCGAATACCCGCACCCGCGAAATCGCGCACAAGATCGAACAACTGCATGAGGAGCGCGGCGAATCGGCG
ACCGGCCGCGTACTGACGCT

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSESPNWSNPLRDSRDLRLPRIAGPCSLVIFGVTGDLAQKKLLPAVYDLANRGLLPPSFGLTGFARRDWTQERFIEFVKA
AIQAHCRTPFKESTWRNLAAGIRFVQGTFDDQEAFERLSATVQELDRDRGTQGNHAFYMSVPPRAFPQVAKQLAASGLSR
SSEGAWRRVIIEKPFGHDLASAKELDSVVSEVFDPSSVFRIDHYLGKETVQNLLALRFANAMYEPIWNANYVDHVQITMA
EDIGIGGRAGYYDGIGAARDVIQNHLLQLMALTAMEEPVSFTAKDLTAEKTKVLSAVRLPKDLAANTARGQYAKGWQGSH
EVVGYLEEKGIDPKSTTETYAAIRLDIDTRRWAGVPFYLRCGKRLGKRVTEIAVMFKRAPHLPFEQTAVRELGKNAIVIR
VQPDEGVTMRFGAKVPGGSTMEVRDVNMDFSYGRSFTENSPEAYERLILDVLLGDPPLFPTTEEVNLSWEILDPIERFWS
TLGQPQAYRSGTWGPTQADDMLARDGRHWRMP

Sequences:

>Translated_512_residues
MSESPNWSNPLRDSRDLRLPRIAGPCSLVIFGVTGDLAQKKLLPAVYDLANRGLLPPSFGLTGFARRDWTQERFIEFVKA
AIQAHCRTPFKESTWRNLAAGIRFVQGTFDDQEAFERLSATVQELDRDRGTQGNHAFYMSVPPRAFPQVAKQLAASGLSR
SSEGAWRRVIIEKPFGHDLASAKELDSVVSEVFDPSSVFRIDHYLGKETVQNLLALRFANAMYEPIWNANYVDHVQITMA
EDIGIGGRAGYYDGIGAARDVIQNHLLQLMALTAMEEPVSFTAKDLTAEKTKVLSAVRLPKDLAANTARGQYAKGWQGSH
EVVGYLEEKGIDPKSTTETYAAIRLDIDTRRWAGVPFYLRCGKRLGKRVTEIAVMFKRAPHLPFEQTAVRELGKNAIVIR
VQPDEGVTMRFGAKVPGGSTMEVRDVNMDFSYGRSFTENSPEAYERLILDVLLGDPPLFPTTEEVNLSWEILDPIERFWS
TLGQPQAYRSGTWGPTQADDMLARDGRHWRMP
>Mature_511_residues
SESPNWSNPLRDSRDLRLPRIAGPCSLVIFGVTGDLAQKKLLPAVYDLANRGLLPPSFGLTGFARRDWTQERFIEFVKAA
IQAHCRTPFKESTWRNLAAGIRFVQGTFDDQEAFERLSATVQELDRDRGTQGNHAFYMSVPPRAFPQVAKQLAASGLSRS
SEGAWRRVIIEKPFGHDLASAKELDSVVSEVFDPSSVFRIDHYLGKETVQNLLALRFANAMYEPIWNANYVDHVQITMAE
DIGIGGRAGYYDGIGAARDVIQNHLLQLMALTAMEEPVSFTAKDLTAEKTKVLSAVRLPKDLAANTARGQYAKGWQGSHE
VVGYLEEKGIDPKSTTETYAAIRLDIDTRRWAGVPFYLRCGKRLGKRVTEIAVMFKRAPHLPFEQTAVRELGKNAIVIRV
QPDEGVTMRFGAKVPGGSTMEVRDVNMDFSYGRSFTENSPEAYERLILDVLLGDPPLFPTTEEVNLSWEILDPIERFWST
LGQPQAYRSGTWGPTQADDMLARDGRHWRMP

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=489, Percent_Identity=37.8323108384458, Blast_Score=321, Evalue=9e-88,
Organism=Homo sapiens, GI108773793, Length=489, Percent_Identity=37.8323108384458, Blast_Score=321, Evalue=1e-87,
Organism=Homo sapiens, GI52145310, Length=376, Percent_Identity=33.2446808510638, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1788158, Length=498, Percent_Identity=40.7630522088353, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17538218, Length=511, Percent_Identity=37.1819960861057, Blast_Score=349, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6324088, Length=493, Percent_Identity=37.525354969574, Blast_Score=312, Evalue=6e-86,
Organism=Drosophila melanogaster, GI24643350, Length=484, Percent_Identity=36.5702479338843, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24643352, Length=484, Percent_Identity=36.5702479338843, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI221513548, Length=491, Percent_Identity=29.938900203666, Blast_Score=209, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57372; Mature: 57241

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESPNWSNPLRDSRDLRLPRIAGPCSLVIFGVTGDLAQKKLLPAVYDLANRGLLPPSFG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
LTGFARRDWTQERFIEFVKAAIQAHCRTPFKESTWRNLAAGIRFVQGTFDDQEAFERLSA
CCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TVQELDRDRGTQGNHAFYMSVPPRAFPQVAKQLAASGLSRSSEGAWRRVIIEKPFGHDLA
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
SAKELDSVVSEVFDPSSVFRIDHYLGKETVQNLLALRFANAMYEPIWNANYVDHVQITMA
HHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
EDIGIGGRAGYYDGIGAARDVIQNHLLQLMALTAMEEPVSFTAKDLTAEKTKVLSAVRLP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
KDLAANTARGQYAKGWQGSHEVVGYLEEKGIDPKSTTETYAAIRLDIDTRRWAGVPFYLR
HHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHCCCCHHHH
CGKRLGKRVTEIAVMFKRAPHLPFEQTAVRELGKNAIVIRVQPDEGVTMRFGAKVPGGST
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCE
MEVRDVNMDFSYGRSFTENSPEAYERLILDVLLGDPPLFPTTEEVNLSWEILDPIERFWS
EEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHH
TLGQPQAYRSGTWGPTQADDMLARDGRHWRMP
HHCCCCHHCCCCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SESPNWSNPLRDSRDLRLPRIAGPCSLVIFGVTGDLAQKKLLPAVYDLANRGLLPPSFG
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
LTGFARRDWTQERFIEFVKAAIQAHCRTPFKESTWRNLAAGIRFVQGTFDDQEAFERLSA
CCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TVQELDRDRGTQGNHAFYMSVPPRAFPQVAKQLAASGLSRSSEGAWRRVIIEKPFGHDLA
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
SAKELDSVVSEVFDPSSVFRIDHYLGKETVQNLLALRFANAMYEPIWNANYVDHVQITMA
HHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
EDIGIGGRAGYYDGIGAARDVIQNHLLQLMALTAMEEPVSFTAKDLTAEKTKVLSAVRLP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
KDLAANTARGQYAKGWQGSHEVVGYLEEKGIDPKSTTETYAAIRLDIDTRRWAGVPFYLR
HHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHCCCCHHHH
CGKRLGKRVTEIAVMFKRAPHLPFEQTAVRELGKNAIVIRVQPDEGVTMRFGAKVPGGST
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCE
MEVRDVNMDFSYGRSFTENSPEAYERLILDVLLGDPPLFPTTEEVNLSWEILDPIERFWS
EEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHH
TLGQPQAYRSGTWGPTQADDMLARDGRHWRMP
HHCCCCHHCCCCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]