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The map label for this gene is fba [H]

Identifier: 213691041

GI number: 213691041

Start: 141845

End: 142933

Strand: Direct

Name: fba [H]

Synonym: Blon_0120

Alternate gene names: 213691041

Gene position: 141845-142933 (Clockwise)

Preceding gene: 213691039

Following gene: 213691042

Centisome position: 5.01

GC content: 67.77

Gene sequence:

>1089_bases
ATGACTATCGCAACTGCCGAACGCTATGCCGAAATGCTGGATGCCGCCCGCCACGGCGGATACGCCTATCCCGCGATCAA
CGTGACCAGCACGCAGACGCTCAACGCCGCGCTGCAGGGATTCGCCGAGGCCGAGTCCGACGGCATCATCCAGGTGTCGG
TCGGCGGCTCCTCCTACTTCTCCGGCCAAAGCGTGAACGACCGCGTGGTCGGGTCGCTCGCGTTCGCCGCATTCGCGCAC
GAGGTGGCGAAGCGCTACCCGAACATCACGGTCGCGCTGCACACCGACCATTGCGCCAAGCAGTACCTGGACGGCTGGGT
CCGCCCGCTGCTCGCGCACGAGGCCGAACAGGTCAAGCGCGGCGAAGAGCCGACGTTCCAGTCGCATATGTGGGACGGCT
CGACTGTGCCGCTGGAGGAGAACCTGGACATCGCCGCGGAGCTGCTCGAGAAATCCGTCCGCGCGCATACGGTGCTGGAG
ATCGAGATCGGCGCGGTCGGCGGCGAGGAGGACGGCCATTCCGCGGAGATCAACGAAAAGCTGTATTCCACGCCGACCGA
CGGCGTGCGCGTGGCGGAGCGGCTCGGCCTCGGCGAGCACGGCCGCTATATGGCCGCTTTCACCTTCGGCAACGTGCATG
GCGCATACAAGCCGGGTGTGGTCAAGCTCCGCCCGGAACTGCTGCGCGACATCCAGTCCGAAGTGTGGGACGCGGCCCTC
GACGGCCGTCTTGGGTCGCTGGGCGCGTCGGCGGTGTCCACGTGCGCGCTGCCGGACATGCCCGAGCGCAAGCCCTTCGC
GCTGGTGTTCCACGGCGGTTCCGGCTCCACGCCCGACGAGATCGCCCGCGCGGTGAGCTACGGCGTGGTCAAGATGAACA
TCGACACGGACACGCAGTACGCCTTCACGCGCGCGGTCGCCGGCCACATGTTCGCGCATTACGACGCCGTGCTCAAGATC
GACGGCGAGGTCGGCAACAAGAAGCTGTACGACCCGCGCTCCTGGGGCCGCGAGGCCGAATCGGCCATGGCCGCCCGCGT
GGTCGAGGCGTGCCGGCAGCTCGGCTCGGCCGGCAAGGCATTGAAGTAG

Upstream 100 bases:

>100_bases
TGAGCTCCGCGCCTCGCGGGCAAGGTGATCTTGCGCACATTCGCCGCCGAGGCCTCCCCGACAATGCGATTCGTCACTCG
GCGGCGGGATAATGGAAGCC

Downstream 100 bases:

>100_bases
CGAAGCGGCGGGCGGCACCGCTGACGGGCTGCGGTCATGTGATGAGATCAGGACATTGATGGATTGTTCGCCAGACGGAT
GGGGACTGCAATGAGCGCAC

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTIATAERYAEMLDAARHGGYAYPAINVTSTQTLNAALQGFAEAESDGIIQVSVGGSSYFSGQSVNDRVVGSLAFAAFAH
EVAKRYPNITVALHTDHCAKQYLDGWVRPLLAHEAEQVKRGEEPTFQSHMWDGSTVPLEENLDIAAELLEKSVRAHTVLE
IEIGAVGGEEDGHSAEINEKLYSTPTDGVRVAERLGLGEHGRYMAAFTFGNVHGAYKPGVVKLRPELLRDIQSEVWDAAL
DGRLGSLGASAVSTCALPDMPERKPFALVFHGGSGSTPDEIARAVSYGVVKMNIDTDTQYAFTRAVAGHMFAHYDAVLKI
DGEVGNKKLYDPRSWGREAESAMAARVVEACRQLGSAGKALK

Sequences:

>Translated_362_residues
MTIATAERYAEMLDAARHGGYAYPAINVTSTQTLNAALQGFAEAESDGIIQVSVGGSSYFSGQSVNDRVVGSLAFAAFAH
EVAKRYPNITVALHTDHCAKQYLDGWVRPLLAHEAEQVKRGEEPTFQSHMWDGSTVPLEENLDIAAELLEKSVRAHTVLE
IEIGAVGGEEDGHSAEINEKLYSTPTDGVRVAERLGLGEHGRYMAAFTFGNVHGAYKPGVVKLRPELLRDIQSEVWDAAL
DGRLGSLGASAVSTCALPDMPERKPFALVFHGGSGSTPDEIARAVSYGVVKMNIDTDTQYAFTRAVAGHMFAHYDAVLKI
DGEVGNKKLYDPRSWGREAESAMAARVVEACRQLGSAGKALK
>Mature_361_residues
TIATAERYAEMLDAARHGGYAYPAINVTSTQTLNAALQGFAEAESDGIIQVSVGGSSYFSGQSVNDRVVGSLAFAAFAHE
VAKRYPNITVALHTDHCAKQYLDGWVRPLLAHEAEQVKRGEEPTFQSHMWDGSTVPLEENLDIAAELLEKSVRAHTVLEI
EIGAVGGEEDGHSAEINEKLYSTPTDGVRVAERLGLGEHGRYMAAFTFGNVHGAYKPGVVKLRPELLRDIQSEVWDAALD
GRLGSLGASAVSTCALPDMPERKPFALVFHGGSGSTPDEIARAVSYGVVKMNIDTDTQYAFTRAVAGHMFAHYDAVLKID
GEVGNKKLYDPRSWGREAESAMAARVVEACRQLGSAGKALK

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789293, Length=370, Percent_Identity=37.027027027027, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI87082041, Length=350, Percent_Identity=24.2857142857143, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789526, Length=350, Percent_Identity=25.1428571428571, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322790, Length=360, Percent_Identity=35.5555555555556, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006411
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38981; Mature: 38850

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIATAERYAEMLDAARHGGYAYPAINVTSTQTLNAALQGFAEAESDGIIQVSVGGSSYF
CCCCCHHHHHHHHHHHHCCCEECCEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
SGQSVNDRVVGSLAFAAFAHEVAKRYPNITVALHTDHCAKQYLDGWVRPLLAHEAEQVKR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
GEEPTFQSHMWDGSTVPLEENLDIAAELLEKSVRAHTVLEIEIGAVGGEEDGHSAEINEK
CCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCHHHHH
LYSTPTDGVRVAERLGLGEHGRYMAAFTFGNVHGAYKPGVVKLRPELLRDIQSEVWDAAL
HHCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
DGRLGSLGASAVSTCALPDMPERKPFALVFHGGSGSTPDEIARAVSYGVVKMNIDTDTQY
CCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCHH
AFTRAVAGHMFAHYDAVLKIDGEVGNKKLYDPRSWGREAESAMAARVVEACRQLGSAGKA
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCCC
LK
CC
>Mature Secondary Structure 
TIATAERYAEMLDAARHGGYAYPAINVTSTQTLNAALQGFAEAESDGIIQVSVGGSSYF
CCCCHHHHHHHHHHHHCCCEECCEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
SGQSVNDRVVGSLAFAAFAHEVAKRYPNITVALHTDHCAKQYLDGWVRPLLAHEAEQVKR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
GEEPTFQSHMWDGSTVPLEENLDIAAELLEKSVRAHTVLEIEIGAVGGEEDGHSAEINEK
CCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCHHHHH
LYSTPTDGVRVAERLGLGEHGRYMAAFTFGNVHGAYKPGVVKLRPELLRDIQSEVWDAAL
HHCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
DGRLGSLGASAVSTCALPDMPERKPFALVFHGGSGSTPDEIARAVSYGVVKMNIDTDTQY
CCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCHH
AFTRAVAGHMFAHYDAVLKIDGEVGNKKLYDPRSWGREAESAMAARVVEACRQLGSAGKA
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCCC
LK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11287146 [H]