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The map label for this gene is yciC [H]

Identifier: 213159153

GI number: 213159153

Start: 3988986

End: 3990251

Strand: Reverse

Name: yciC [H]

Synonym: AB57_3864

Alternate gene names: 213159153

Gene position: 3990251-3988986 (Counterclockwise)

Preceding gene: 213159154

Following gene: 213159151

Centisome position: 98.51

GC content: 44.08

Gene sequence:

>1266_bases
ATGATCAGTTTAAATATTATTCAAAGAGATCAAGCCATGCACACTGCAATCGCCAACTCATTTGCCAAGCTTCCCGTCAC
TGTTTTATCGGGCTTTTTGGGTGCAGGAAAGACCACATTACTCAACCATATTTTAAATAATCGCGAAGGCCGCCGTATTG
CCGTGATTGTTAATGATATGTCTGAGGTGAATATTGATGCGGCATTAGTACGCGAAGGTGGGGCAGAGCTTTCAAGAACA
GATGAAAAACTGGTTGAAATGAGTAATGGCTGTATCTGCTGTACGTTACGAGAAGACTTATTGGTTGAAGTGAGACGTTT
AGCCGATGAAGGACGCTTTGACCAATTGGTGATTGAGTCAACAGGCATTTCAGAACCTTTACCTGTGGCAGAAACTTTTA
CTTTTGAAGATGAAGATGGAAACTCACTCAATGAGTTTGCTCGACTCGACACTATGGTTACGGTAGTCGATGCTTTTAAC
TTTCTTAAAGACTACAGTTCAGTTGACTCCCTACAACAACGCGGCGAATCATTAGGCGAGCAAGATGAGAGAACTGTGGT
TGACCTTCTTATCGATCAGATTGAGTTTTGTGATGTGATTGTGCTGAATAAAATTGATTTGATTGATCAGGCTCAGCAAG
ACCAGCTTATCGCCATTTTAAAAACGTTAAACCCGCGTGCCCGAATTGAAATTGCTCAATTTGGAAAGGTCGCTTTAGAT
AAAATCTTAAATACACAGTTATTTGATTTTGATGAAGCCGCGCAAGCACCGGGTTGGTTAAAAGAGTTACGCGGCGAGCA
TACACCTGAAACTGAAGAGTATGGCATTAGTAGCTTTGTTTACCGTGCCCGCCGACCTTTCCATCCAGAGCGTTTTTATG
ATTTGGTACAGGCTGAATGGCCGGGAGTCGTGCGTTCCAAAGGCTTTTTCTGGCTGGCTGCCGAACCGACATTGGCTTAT
TCATGGTCGCAAGCGGGTGCAATGGCTCGACACGGTTTAGCTGGTTATTGGTGGGCAGCCGTTGCGGAAGAAGACTGGCC
GAGTGACCTAGCCAGCATTGAACAAATTAAGAAAAACTGGGATGCCCGCACAGGTGATGCGCGTCAGGAGCTGGTTTTAA
TTGGTATGCAAATGGATGAGCAAGCTTTAATACAACGCTTGGATAGCTGCTTGTTAAGCGATGAAGAAATAGCTTTAGGT
CCGCAAGTTTGGCAGAGCTGGTCTAATCCTTTTAAGCAAGATGATGAAACGATGTTGATTGCTTAA

Upstream 100 bases:

>100_bases
CTGGAATAAAAACTTGATCAATAGTTATGTTATAACATAACATTATTGTGGTTTAGAAATAGATTACGCCTGTGATCTGG
CCATATTTAAATGGCCAGCC

Downstream 100 bases:

>100_bases
TAAAAAAGCCCCTATTTTCAAGGGGCTTATTTTTTTAAGATTTATCTTTAATAAAAACCTTTCGAATGTAGCTGTTAAGC
GGGGTGGAATAATATTTTTC

Product: CobW/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MISLNIIQRDQAMHTAIANSFAKLPVTVLSGFLGAGKTTLLNHILNNREGRRIAVIVNDMSEVNIDAALVREGGAELSRT
DEKLVEMSNGCICCTLREDLLVEVRRLADEGRFDQLVIESTGISEPLPVAETFTFEDEDGNSLNEFARLDTMVTVVDAFN
FLKDYSSVDSLQQRGESLGEQDERTVVDLLIDQIEFCDVIVLNKIDLIDQAQQDQLIAILKTLNPRARIEIAQFGKVALD
KILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGISSFVYRARRPFHPERFYDLVQAEWPGVVRSKGFFWLAAEPTLAY
SWSQAGAMARHGLAGYWWAAVAEEDWPSDLASIEQIKKNWDARTGDARQELVLIGMQMDEQALIQRLDSCLLSDEEIALG
PQVWQSWSNPFKQDDETMLIA

Sequences:

>Translated_421_residues
MISLNIIQRDQAMHTAIANSFAKLPVTVLSGFLGAGKTTLLNHILNNREGRRIAVIVNDMSEVNIDAALVREGGAELSRT
DEKLVEMSNGCICCTLREDLLVEVRRLADEGRFDQLVIESTGISEPLPVAETFTFEDEDGNSLNEFARLDTMVTVVDAFN
FLKDYSSVDSLQQRGESLGEQDERTVVDLLIDQIEFCDVIVLNKIDLIDQAQQDQLIAILKTLNPRARIEIAQFGKVALD
KILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGISSFVYRARRPFHPERFYDLVQAEWPGVVRSKGFFWLAAEPTLAY
SWSQAGAMARHGLAGYWWAAVAEEDWPSDLASIEQIKKNWDARTGDARQELVLIGMQMDEQALIQRLDSCLLSDEEIALG
PQVWQSWSNPFKQDDETMLIA
>Mature_421_residues
MISLNIIQRDQAMHTAIANSFAKLPVTVLSGFLGAGKTTLLNHILNNREGRRIAVIVNDMSEVNIDAALVREGGAELSRT
DEKLVEMSNGCICCTLREDLLVEVRRLADEGRFDQLVIESTGISEPLPVAETFTFEDEDGNSLNEFARLDTMVTVVDAFN
FLKDYSSVDSLQQRGESLGEQDERTVVDLLIDQIEFCDVIVLNKIDLIDQAQQDQLIAILKTLNPRARIEIAQFGKVALD
KILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGISSFVYRARRPFHPERFYDLVQAEWPGVVRSKGFFWLAAEPTLAY
SWSQAGAMARHGLAGYWWAAVAEEDWPSDLASIEQIKKNWDARTGDARQELVLIGMQMDEQALIQRLDSCLLSDEEIALG
PQVWQSWSNPFKQDDETMLIA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI146231952, Length=404, Percent_Identity=26.4851485148515, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI33469141, Length=261, Percent_Identity=31.0344827586207, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI148727351, Length=404, Percent_Identity=26.2376237623762, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI126722884, Length=261, Percent_Identity=30.6513409961686, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI223941779, Length=210, Percent_Identity=32.3809523809524, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI223941776, Length=249, Percent_Identity=29.3172690763052, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI119120938, Length=147, Percent_Identity=37.4149659863946, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI87082430, Length=304, Percent_Identity=29.6052631578947, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788499, Length=110, Percent_Identity=35.4545454545455, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324356, Length=282, Percent_Identity=26.241134751773, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 47403; Mature: 47403

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLNIIQRDQAMHTAIANSFAKLPVTVLSGFLGAGKTTLLNHILNNREGRRIAVIVNDM
CEEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECC
SEVNIDAALVREGGAELSRTDEKLVEMSNGCICCTLREDLLVEVRRLADEGRFDQLVIES
CCCCCHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEEC
TGISEPLPVAETFTFEDEDGNSLNEFARLDTMVTVVDAFNFLKDYSSVDSLQQRGESLGE
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDERTVVDLLIDQIEFCDVIVLNKIDLIDQAQQDQLIAILKTLNPRARIEIAQFGKVALD
HHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
KILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGISSFVYRARRPFHPERFYDLVQAEW
HHHCCHHCCCHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
PGVVRSKGFFWLAAEPTLAYSWSQAGAMARHGLAGYWWAAVAEEDWPSDLASIEQIKKNW
CCCEECCCEEEEECCCCEEECHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHC
DARTGDARQELVLIGMQMDEQALIQRLDSCLLSDEEIALGPQVWQSWSNPFKQDDETMLI
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEE
A
C
>Mature Secondary Structure
MISLNIIQRDQAMHTAIANSFAKLPVTVLSGFLGAGKTTLLNHILNNREGRRIAVIVNDM
CEEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECC
SEVNIDAALVREGGAELSRTDEKLVEMSNGCICCTLREDLLVEVRRLADEGRFDQLVIES
CCCCCHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEEC
TGISEPLPVAETFTFEDEDGNSLNEFARLDTMVTVVDAFNFLKDYSSVDSLQQRGESLGE
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDERTVVDLLIDQIEFCDVIVLNKIDLIDQAQQDQLIAILKTLNPRARIEIAQFGKVALD
HHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
KILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGISSFVYRARRPFHPERFYDLVQAEW
HHHCCHHCCCHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
PGVVRSKGFFWLAAEPTLAYSWSQAGAMARHGLAGYWWAAVAEEDWPSDLASIEQIKKNW
CCCEECCCEEEEECCCCEEECHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHC
DARTGDARQELVLIGMQMDEQALIQRLDSCLLSDEEIALGPQVWQSWSNPFKQDDETMLI
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEE
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]