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The map label for this gene is yedX [C]

Identifier: 213159093

GI number: 213159093

Start: 3922220

End: 3922543

Strand: Direct

Name: yedX [C]

Synonym: AB57_3803

Alternate gene names: 213159093

Gene position: 3922220-3922543 (Clockwise)

Preceding gene: 213159092

Following gene: 213159094

Centisome position: 96.83

GC content: 40.12

Gene sequence:

>324_bases
ATGATCAGCACTCATATTTTAGATACGAATTTAGGTAAACCGGCGGCACAGGTCGAAGTGAAGTTGTTTCATGCAGCCAC
TCATGAACTGATAGCGACTGCAATTACCAACCAAGATGGGCGAGTGAGTGATTTTGGAATAAAAAACTTAGGCAAAGGTG
CTTATCAACTTGAATTTGAAGTTGCCCCTTATTTTTCATCACAGCAAATCAAAACTTTTTTCCCCCGTGTTTGTATTCAA
TTTTTCATAGAAGACACCAATCAGCATTACCACATTCCATTACTGATCAGCCCGTTTGCTTATTCCACTTATCGCGGCAG
CTAA

Upstream 100 bases:

>100_bases
TCCATCAACGTCTTCAAAACAACTTAGCTATTGAAAAAACAATTGTACATGAGCAACTCGCTGCAATTGCTCTATTACGT
CTATCTCAGGAAGTACAAGC

Downstream 100 bases:

>100_bases
CTCAAATATAAATAGGAGAAAAATATGAATCATCAGCAAAAGAATGCGATTTCTCCAGAGCATGAATATTTAGGAATTTC
CAAAAGTTTTGCTTACGGCT

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MISTHILDTNLGKPAAQVEVKLFHAATHELIATAITNQDGRVSDFGIKNLGKGAYQLEFEVAPYFSSQQIKTFFPRVCIQ
FFIEDTNQHYHIPLLISPFAYSTYRGS

Sequences:

>Translated_107_residues
MISTHILDTNLGKPAAQVEVKLFHAATHELIATAITNQDGRVSDFGIKNLGKGAYQLEFEVAPYFSSQQIKTFFPRVCIQ
FFIEDTNQHYHIPLLISPFAYSTYRGS
>Mature_107_residues
MISTHILDTNLGKPAAQVEVKLFHAATHELIATAITNQDGRVSDFGIKNLGKGAYQLEFEVAPYFSSQQIKTFFPRVCIQ
FFIEDTNQHYHIPLLISPFAYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=110, Percent_Identity=40.9090909090909, Blast_Score=92, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115532922, Length=112, Percent_Identity=38.3928571428571, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532920, Length=112, Percent_Identity=38.3928571428571, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115534555, Length=112, Percent_Identity=37.5, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24652571, Length=109, Percent_Identity=40.3669724770642, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12066; Mature: 12066

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTHILDTNLGKPAAQVEVKLFHAATHELIATAITNQDGRVSDFGIKNLGKGAYQLEFE
CCCEEEEECCCCCCCHHEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEE
VAPYFSSQQIKTFFPRVCIQFFIEDTNQHYHIPLLISPFAYSTYRGS
ECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MISTHILDTNLGKPAAQVEVKLFHAATHELIATAITNQDGRVSDFGIKNLGKGAYQLEFE
CCCEEEEECCCCCCCHHEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEE
VAPYFSSQQIKTFFPRVCIQFFIEDTNQHYHIPLLISPFAYSTYRGS
ECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]