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The map label for this gene is ftsA [H]

Identifier: 213159073

GI number: 213159073

Start: 3901782

End: 3903044

Strand: Reverse

Name: ftsA [H]

Synonym: AB57_3783

Alternate gene names: 213159073

Gene position: 3903044-3901782 (Counterclockwise)

Preceding gene: 213159074

Following gene: 213159072

Centisome position: 96.36

GC content: 43.94

Gene sequence:

>1263_bases
ATGAGTGAAGCTGTTCCCTCAGTTGTTGCGATTGACATTGGGACGCATAAAGTTTCAGTTTTGATTGGAAAAATTCATGC
GCCGGATAACATTCAGGTTATCGGTATGGCAACTGCTCGCAATCGAGGCATGAACAAAGGAAAAATTGTAAGTCTCGATA
AAGTCATTGCTGCGATTAAAAACGCTGTTGCTGAAGCGGAAAATATGGCCGAATGTCGCATTCATAGTGCGTGGGTATCT
ATTCCGAGTACCGAGCTACAAAGTTTCTATGCTTCCGGACGCACACCTGTTGCTAACCCGGCGCATGTGATTACAACCAA
TGAAGTTGTACGTGCATTAGAGTTGGCAAAAGCAAGCCATGTGACTTCTGACTATTATCTAGCGAGTGCGGTACCATTAG
GATTTGAATTAGGCGACTCATCTGAATGGGTTCAAAACCCAATCAATATGACCGCTCACAGCATGACTGGTCATTATCAG
CTTATGATGATGCCGATTGCCACTATGCAAAACCTTGATCGTGCCATGAAAGGCGCGAACATTGGAGTTGAGAAAATGGT
AGTTTCTTGCTTGGCTACGGCTGAGGCAAGTTTGCTTAAAGATGAAAAAGAATATGGTGTCTGTCTTGTCGATATTGGTG
CAGGTATTACCAATCTGGCAGTTTATTTAGATGGCCGTTTGGCTTTAGCACGCACCTTACAGCGTGGAGGTGAGCATGTG
ACACGTGATATTGCTGCCGTGTTACAAACAACCACTGAAGAAGCTGAACGTATTAAGATTCTGCATGGCTGTGTTGATCT
AAGTGCTGTTAAGCCTGACCATATGATTCAAGTACAGGGTATTGATGGTCCGCAAACGATTAGCCGAATTGAGTTAGCGG
AAATTATTATTGCTCGTTATGAAGAGATTTTCAGCCAGATTCGCGAAGAACTCGAACAAAGCGGTGCAATCCATGGTCTA
TATCATGGTGTTGTATTGACTGGTGATGCTTGCCAGATTGAAGGTATGGTAAGTTTGGCGCGTCGTATGTTAGGTGTGTC
TGCCCATCTAGGTAATCCGCCATTACAGGTGTATGCTGATGATCAGCATCAAGCTGCATTACGCCGCTCAATGTATGCAA
CAGCAGCTGGTTTACTTATGTTTAGCCAAAGTGAATTACAAGAAGCTGTTGAGGAGCCTGAAGAGGGAAATGACCGTTCG
GTATGGGAACGAATGGTGAATGGCTGGAATGCTTTTAATAGCAAACTTAAAGCCATTTTTTAG

Upstream 100 bases:

>100_bases
TGACACAAGCATTGCAGGTGGTACAAAAGCAAAGCCATAATACGTGGCTTTAAAATAGGCAATTTGCCTGGTATTAGACA
ACAAAGAAATGGTATGAGTG

Downstream 100 bases:

>100_bases
GATGTATGTATTTATTGGTAGAATTGTTAGGAAGTTGTAAGAGAAAACCACTGTACTTGACAAGGTTGGTATTGCACAGC
ATTCTTAAAATTAGTTATTT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSEAVPSVVAIDIGTHKVSVLIGKIHAPDNIQVIGMATARNRGMNKGKIVSLDKVIAAIKNAVAEAENMAECRIHSAWVS
IPSTELQSFYASGRTPVANPAHVITTNEVVRALELAKASHVTSDYYLASAVPLGFELGDSSEWVQNPINMTAHSMTGHYQ
LMMMPIATMQNLDRAMKGANIGVEKMVVSCLATAEASLLKDEKEYGVCLVDIGAGITNLAVYLDGRLALARTLQRGGEHV
TRDIAAVLQTTTEEAERIKILHGCVDLSAVKPDHMIQVQGIDGPQTISRIELAEIIIARYEEIFSQIREELEQSGAIHGL
YHGVVLTGDACQIEGMVSLARRMLGVSAHLGNPPLQVYADDQHQAALRRSMYATAAGLLMFSQSELQEAVEEPEEGNDRS
VWERMVNGWNAFNSKLKAIF

Sequences:

>Translated_420_residues
MSEAVPSVVAIDIGTHKVSVLIGKIHAPDNIQVIGMATARNRGMNKGKIVSLDKVIAAIKNAVAEAENMAECRIHSAWVS
IPSTELQSFYASGRTPVANPAHVITTNEVVRALELAKASHVTSDYYLASAVPLGFELGDSSEWVQNPINMTAHSMTGHYQ
LMMMPIATMQNLDRAMKGANIGVEKMVVSCLATAEASLLKDEKEYGVCLVDIGAGITNLAVYLDGRLALARTLQRGGEHV
TRDIAAVLQTTTEEAERIKILHGCVDLSAVKPDHMIQVQGIDGPQTISRIELAEIIIARYEEIFSQIREELEQSGAIHGL
YHGVVLTGDACQIEGMVSLARRMLGVSAHLGNPPLQVYADDQHQAALRRSMYATAAGLLMFSQSELQEAVEEPEEGNDRS
VWERMVNGWNAFNSKLKAIF
>Mature_419_residues
SEAVPSVVAIDIGTHKVSVLIGKIHAPDNIQVIGMATARNRGMNKGKIVSLDKVIAAIKNAVAEAENMAECRIHSAWVSI
PSTELQSFYASGRTPVANPAHVITTNEVVRALELAKASHVTSDYYLASAVPLGFELGDSSEWVQNPINMTAHSMTGHYQL
MMMPIATMQNLDRAMKGANIGVEKMVVSCLATAEASLLKDEKEYGVCLVDIGAGITNLAVYLDGRLALARTLQRGGEHVT
RDIAAVLQTTTEEAERIKILHGCVDLSAVKPDHMIQVQGIDGPQTISRIELAEIIIARYEEIFSQIREELEQSGAIHGLY
HGVVLTGDACQIEGMVSLARRMLGVSAHLGNPPLQVYADDQHQAALRRSMYATAAGLLMFSQSELQEAVEEPEEGNDRSV
WERMVNGWNAFNSKLKAIF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=417, Percent_Identity=30.4556354916067, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45595; Mature: 45464

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAVPSVVAIDIGTHKVSVLIGKIHAPDNIQVIGMATARNRGMNKGKIVSLDKVIAAIK
CCCCCCCEEEEECCCEEEEEEEEEECCCCCEEEEEEEEHHCCCCCCCCEEEHHHHHHHHH
NAVAEAENMAECRIHSAWVSIPSTELQSFYASGRTPVANPAHVITTNEVVRALELAKASH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHC
VTSDYYLASAVPLGFELGDSSEWVQNPINMTAHSMTGHYQLMMMPIATMQNLDRAMKGAN
CCCCHHHHHCCCCCEEECCCHHHHHCCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCC
IGVEKMVVSCLATAEASLLKDEKEYGVCLVDIGAGITNLAVYLDGRLALARTLQRGGEHV
CCHHHHHHHHHHHHHHHHHCCCHHCCEEEEECCCCCEEEEEEECCHHHHHHHHHHCCHHH
TRDIAAVLQTTTEEAERIKILHGCVDLSAVKPDHMIQVQGIDGPQTISRIELAEIIIARY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
EEIFSQIREELEQSGAIHGLYHGVVLTGDACQIEGMVSLARRMLGVSAHLGNPPLQVYAD
HHHHHHHHHHHHHCCCEEEEEECEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DQHQAALRRSMYATAAGLLMFSQSELQEAVEEPEEGNDRSVWERMVNGWNAFNSKLKAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEAVPSVVAIDIGTHKVSVLIGKIHAPDNIQVIGMATARNRGMNKGKIVSLDKVIAAIK
CCCCCCEEEEECCCEEEEEEEEEECCCCCEEEEEEEEHHCCCCCCCCEEEHHHHHHHHH
NAVAEAENMAECRIHSAWVSIPSTELQSFYASGRTPVANPAHVITTNEVVRALELAKASH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHC
VTSDYYLASAVPLGFELGDSSEWVQNPINMTAHSMTGHYQLMMMPIATMQNLDRAMKGAN
CCCCHHHHHCCCCCEEECCCHHHHHCCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCC
IGVEKMVVSCLATAEASLLKDEKEYGVCLVDIGAGITNLAVYLDGRLALARTLQRGGEHV
CCHHHHHHHHHHHHHHHHHCCCHHCCEEEEECCCCCEEEEEEECCHHHHHHHHHHCCHHH
TRDIAAVLQTTTEEAERIKILHGCVDLSAVKPDHMIQVQGIDGPQTISRIELAEIIIARY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
EEIFSQIREELEQSGAIHGLYHGVVLTGDACQIEGMVSLARRMLGVSAHLGNPPLQVYAD
HHHHHHHHHHHHHCCCEEEEEECEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DQHQAALRRSMYATAAGLLMFSQSELQEAVEEPEEGNDRSVWERMVNGWNAFNSKLKAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]