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The map label for this gene is actP [H]

Identifier: 213159039

GI number: 213159039

Start: 3861734

End: 3863449

Strand: Reverse

Name: actP [H]

Synonym: AB57_3747

Alternate gene names: 213159039

Gene position: 3863449-3861734 (Counterclockwise)

Preceding gene: 213159040

Following gene: 213159038

Centisome position: 95.38

GC content: 42.72

Gene sequence:

>1716_bases
ATGAAATGGAATTCATTAAAAGCGAAAGCCTTATTGGCAGCAGCATCGCTATATTCAACTGTTGCTATGGCAAGCCCGGA
CTTAGGTGAAGCAGAACAGCAAGCCACCAACTGGCATGCCATTATCATGTTTATCATCTTTGTTGGCTTTACCTTATTTA
TTACCAAATGGGCGGCTAAACAAACTCAATCGGCGCAAGACTTCTATACTGCTGGTGGTGGGATCAGTGGTTTCCAAAAC
GGTTTGGCGATTGCGGGTGACTATATGTCAGCAGCGTCATTTCTTGGTATTTCTGCAATGGTGTTTAGCTCAGGTTTTGA
CGGCTTGCTCTATTCACTCGGGTTCATGGTCGGTTGGCCAATCGTTTTATTCTTGGTGGCAGAACGCTTACGTAACCTTG
GTAAATATAACCTTTCAGACGTAGTGTCATTCCGTCTTGAAGAAAAACCAGTTCGTACTTTAGCTGCTTTCAGCTCGCTT
GTTGTAGTCGCGTTCTATTTGATTGCACAAATGGTAGGGGCAGGTCAGCTCATCAAACTATTATTTGGTTTGAACTATAA
CATTGCAGTTGTGATTGTCGGCTTGCTCATGATGGCATACGTTATTTTCGGCGGAATGCTAGCAACCACATGGGTACAAA
TCATTAAAGCAGTGATGTTATTAAGTGGTGCAACGTTCATGGCCTTTATGGTGATGAAAGCGGTTGGTTTCAGCTTTAGT
AATATGTTCACCCAATCAATTGAAGTGTTCAGTAAAGTTCATGATGTAAGCTTTGAAGATGCTGCAAAAATTATGGGACC
AGGTAAACTTGCCGCAAACCCGATTGATGCCTTATCTCTTGGCTTAGCACTCATGTTTGGTACAGCAGGTCTTCCACACA
TTCTTATGCGTTTCTTCACGGTAAAAGACGCAAAAGAAGCGCGTAAATCAGTTGTCGTTGCAACAGGTTTTATTGGTTAC
TTCTATCTTTTAACTTTTATTATTGGTTTCGGTGCGATCCTTTTCGTATCAAACAACCCGCAATTCCTTGATGTTGCGAA
AATGGCAATGACCGGCAAACTTGAGCTTGTTGGTGGTAACAATATGGCAGCCGTGCATTTAAGTGACGCTTTAGGCGGTG
ACTTATTCATGGGCTTCATTTCAGCAGTAGCGTTCGCAACGATTCTTGCTGTTGTTGCTGGTTTAACACTTTCAGGTGCA
TCTGCGATCTCACACGATTTATACGCTAACGTATTTAAAAAAGGTCAAACCACGCCAGCTTCAGAGCTTCGCATGTCAAA
AATCGCGACGCTTGGTTTAGCCATCTTTGCCATGATTTTAGGTATTTTGTTTGAAAAGCAAAACGTAGCATTCATGGTAG
GTTTAGCATTCTCTGTAGCGTGTTGTGCAAACTTCCCAATTCTTGTTCTTTCAATGTTCTGGAAAGGTTTAACAACTCGT
GGTGCGGTCATTGGTGGCGTAGTTGGTCTTGTAACAGCGGTTGTACTCATTATTCTGTCTAAAGCAGTATGGGTAGATAC
TTTAAAAATCTCTGATACCCCAATTAACCCGTTCAATGGTCCTGCATTATTTGCAATGCCTTTGTCGTTCCTTTGCTGCT
GGTTCTTCTCGGTAACTGACAGCTCAGCACGTGCGAAAAAAGAACGCGCTTCTTTCGACGCTCAATATGTTCGTTCAATG
ACAGGTATTGGTGCTTCTGGTGCATCAGACCACTAA

Upstream 100 bases:

>100_bases
GGTGTGTATTCCTATATCGCAAATAATACCCTTGACCAATTGAGTGAAGAAGCGTTGAAGGAAGTTGAAGCCATCACGCA
TGAGAAAGGACTACACTAAT

Downstream 100 bases:

>100_bases
AATCACAACCACTTGAACATCTCAAAAAAGCCCTACGGGGCTTTTTTTATTTATCTCATAAAGTGTTTTGAAAGAAGCTC
CTTAATAAAGAACAACTTGT

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MKWNSLKAKALLAAASLYSTVAMASPDLGEAEQQATNWHAIIMFIIFVGFTLFITKWAAKQTQSAQDFYTAGGGISGFQN
GLAIAGDYMSAASFLGISAMVFSSGFDGLLYSLGFMVGWPIVLFLVAERLRNLGKYNLSDVVSFRLEEKPVRTLAAFSSL
VVVAFYLIAQMVGAGQLIKLLFGLNYNIAVVIVGLLMMAYVIFGGMLATTWVQIIKAVMLLSGATFMAFMVMKAVGFSFS
NMFTQSIEVFSKVHDVSFEDAAKIMGPGKLAANPIDALSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVVVATGFIGY
FYLLTFIIGFGAILFVSNNPQFLDVAKMAMTGKLELVGGNNMAAVHLSDALGGDLFMGFISAVAFATILAVVAGLTLSGA
SAISHDLYANVFKKGQTTPASELRMSKIATLGLAIFAMILGILFEKQNVAFMVGLAFSVACCANFPILVLSMFWKGLTTR
GAVIGGVVGLVTAVVLIILSKAVWVDTLKISDTPINPFNGPALFAMPLSFLCCWFFSVTDSSARAKKERASFDAQYVRSM
TGIGASGASDH

Sequences:

>Translated_571_residues
MKWNSLKAKALLAAASLYSTVAMASPDLGEAEQQATNWHAIIMFIIFVGFTLFITKWAAKQTQSAQDFYTAGGGISGFQN
GLAIAGDYMSAASFLGISAMVFSSGFDGLLYSLGFMVGWPIVLFLVAERLRNLGKYNLSDVVSFRLEEKPVRTLAAFSSL
VVVAFYLIAQMVGAGQLIKLLFGLNYNIAVVIVGLLMMAYVIFGGMLATTWVQIIKAVMLLSGATFMAFMVMKAVGFSFS
NMFTQSIEVFSKVHDVSFEDAAKIMGPGKLAANPIDALSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVVVATGFIGY
FYLLTFIIGFGAILFVSNNPQFLDVAKMAMTGKLELVGGNNMAAVHLSDALGGDLFMGFISAVAFATILAVVAGLTLSGA
SAISHDLYANVFKKGQTTPASELRMSKIATLGLAIFAMILGILFEKQNVAFMVGLAFSVACCANFPILVLSMFWKGLTTR
GAVIGGVVGLVTAVVLIILSKAVWVDTLKISDTPINPFNGPALFAMPLSFLCCWFFSVTDSSARAKKERASFDAQYVRSM
TGIGASGASDH
>Mature_571_residues
MKWNSLKAKALLAAASLYSTVAMASPDLGEAEQQATNWHAIIMFIIFVGFTLFITKWAAKQTQSAQDFYTAGGGISGFQN
GLAIAGDYMSAASFLGISAMVFSSGFDGLLYSLGFMVGWPIVLFLVAERLRNLGKYNLSDVVSFRLEEKPVRTLAAFSSL
VVVAFYLIAQMVGAGQLIKLLFGLNYNIAVVIVGLLMMAYVIFGGMLATTWVQIIKAVMLLSGATFMAFMVMKAVGFSFS
NMFTQSIEVFSKVHDVSFEDAAKIMGPGKLAANPIDALSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVVVATGFIGY
FYLLTFIIGFGAILFVSNNPQFLDVAKMAMTGKLELVGGNNMAAVHLSDALGGDLFMGFISAVAFATILAVVAGLTLSGA
SAISHDLYANVFKKGQTTPASELRMSKIATLGLAIFAMILGILFEKQNVAFMVGLAFSVACCANFPILVLSMFWKGLTTR
GAVIGGVVGLVTAVVLIILSKAVWVDTLKISDTPINPFNGPALFAMPLSFLCCWFFSVTDSSARAKKERASFDAQYVRSM
TGIGASGASDH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=485, Percent_Identity=21.4432989690722, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1790503, Length=543, Percent_Identity=66.4825046040516, Blast_Score=717, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=472, Percent_Identity=25.635593220339, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082237, Length=450, Percent_Identity=22.2222222222222, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60922; Mature: 60922

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA