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The map label for this gene is ompR [H]

Identifier: 213158975

GI number: 213158975

Start: 3796640

End: 3797404

Strand: Direct

Name: ompR [H]

Synonym: AB57_3677

Alternate gene names: 213158975

Gene position: 3796640-3797404 (Clockwise)

Preceding gene: 213158972

Following gene: 213158976

Centisome position: 93.73

GC content: 44.18

Gene sequence:

>765_bases
ATGAGTTTAGTTGTACCTGCTGAACATCCTGAAACCGTACATAACGAAACGGATCGTGTCGAGCGCATTTTAGTGGTCGA
TGACGATGTGCGTTTACGTACCCTCTTGCAACGTTTTTTGGAAGATAAAGGCTTTGTTGTAAAAACTGCCCATGATGCCT
CACAAATGGATCGTTTATTACAACGTGAGTTATTTTCACTTATCGTGCTCGACTTTATGTTGCCCGTTGAAGATGGTTTA
AGTATTTGTCGTCGTTTACGTCAATCAAACATTGATACACCAATTATTATGTTAACTGCACGTGGTAGTGACTCTGACCG
TATTGCTGGTCTTGAAGCCGGCGCAGATGACTATTTACCAAAACCATTTAACCCAAATGAACTTTTAGCACGTATTCGCG
CAGTATTGCGTCGTCAGGTACGTGAAGTCCCGGGTGCGCCAAGCCAACAAGTTGAAGTGGTTAGCTTTGGTCCATGGTCT
CTAGATTTATCTACACGTACACTGACTCGTGAAGGACAAATCGTTACGTTGACTACAGGTGAATTTGCCGTATTAAAAGC
TTTGGTACAGCATCCACGTGAACCTTTAACACGCGACAAGCTCATGAACTTGGCTCGTGGCCGTGAATGGGGTGCAATGG
AACGTTCTATTGATGTTCAAGTGTCTCGTTTACGCCGCTTAATTGAAGATAACCCGGCACGTGCACGTTACATTCAAACT
GTATGGGGCGTAGGCTATGTGTTTGTTCCGGATGGTGCTGAATAA

Upstream 100 bases:

>100_bases
TAGTCTTAACAAGAACATCGGCATTATACTGAGGGCTTGTTGGCAATAAGCCTAACCGATCCAATAATATATAAATTATG
ACTTTAAAAGGGAGTACATC

Downstream 100 bases:

>100_bases
GCTTGAGATAAAATAGAGTGAGTTTAGAGCCAATACCACCGCAAACCTTTACCGACTACGTTGCGTACTCAGAGCGTAAA
CGGACCCGATGGGAACGTTT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSLVVPAEHPETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDASQMDRLLQRELFSLIVLDFMLPVEDGL
SICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGPWS
LDLSTRTLTREGQIVTLTTGEFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
VWGVGYVFVPDGAE

Sequences:

>Translated_254_residues
MSLVVPAEHPETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDASQMDRLLQRELFSLIVLDFMLPVEDGL
SICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGPWS
LDLSTRTLTREGQIVTLTTGEFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
VWGVGYVFVPDGAE
>Mature_253_residues
SLVVPAEHPETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDASQMDRLLQRELFSLIVLDFMLPVEDGLS
ICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGPWSL
DLSTRTLTREGQIVTLTTGEFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQTV
WGVGYVFVPDGAE

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=69.0987124463519, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=40.2542372881356, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=36.6812227074236, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=39.2241379310345, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.8936170212766, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=36.7965367965368, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=34.9137931034483, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786911, Length=238, Percent_Identity=37.3949579831933, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.2173913043478, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=32.5, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.061135371179, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.3275862068966, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=30.8370044052863, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790299, Length=177, Percent_Identity=28.2485875706215, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=171, Percent_Identity=28.6549707602339, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788550, Length=179, Percent_Identity=26.8156424581006, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28816; Mature: 28684

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVVPAEHPETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDASQMDRLL
CCEECCCCCCHHHCCHHHHHEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
QRELFSLIVLDFMLPVEDGLSICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLP
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCC
KPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGPWSLDLSTRTLTREGQIVTLTTG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCHHEEECCCCEEEEECC
EFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VWGVGYVFVPDGAE
HHCCCEEECCCCCC
>Mature Secondary Structure 
SLVVPAEHPETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDASQMDRLL
CEECCCCCCHHHCCHHHHHEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
QRELFSLIVLDFMLPVEDGLSICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLP
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCC
KPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGPWSLDLSTRTLTREGQIVTLTTG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCHHEEECCCCEEEEECC
EFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VWGVGYVFVPDGAE
HHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]