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The map label for this gene is czcC [H]

Identifier: 213158967

GI number: 213158967

Start: 3783095

End: 3784387

Strand: Reverse

Name: czcC [H]

Synonym: AB57_3668

Alternate gene names: 213158967

Gene position: 3784387-3783095 (Counterclockwise)

Preceding gene: 213158968

Following gene: 213158966

Centisome position: 93.43

GC content: 43.16

Gene sequence:

>1293_bases
ATGGCAAATGCTGCGACTGATTTTCAACAGGGCTCTTATACCCAAAAAGCAGCTTTTAGTTTTGAACAGGCATTAGCGCG
AGCACAAAGCTATCAAATTCAACAAGGTGTTTGGCAGGCACAGCAGCAAATGGCTGAGGCGCAATTAAAACAAAGTCGCT
TATGGGCAAATCCAAGTCTTTCTATTGAGCAAACAGGTTTGCAGAGTGACCAAGAAAAAGAACTCGCGATTGGCATCTCT
CAACCTCTAGATATTTTTGGGCAGCGTAAGGCCGCACAGCATTTAGCTAAAGTAGAAATGTCAAAGGTTGACTTGGCCGA
ACAACGTTATAAGGCTGAGCTTGAGTTAATAGTTAAATATTTCTGGTCACAAGTGGCCTTGCTTGAACTTGAAAAGTCTC
TCATTGGAGAACAGTTAGCAGTTAGCCAAGAGAACTTGTCTGCATCGGAAAAGCGTTATCAGGCAGGGAGTATTGCTCAG
GTTGATGTAGATCGAGTACGTATGTCTCACTTGGAAAACCAGCGTTTATATCAGCAGGTCGATTTGAAACTACAAGTTGC
TAAACAACAACTGGCCAACTTATGGGGCGGTGATTCAAATCAGTTCCAACTATCTCAAAGCTCTAATCAGCTGTGGGTAT
TGGCAGCGGATGTAGAGTCTGGTCAAGATCGGCAAAACAATTTGCTAGAGCGCTCTTTTCAACTAGATGCTCTTGCGCAG
CAAGCCACTATTCAACAGCTTAAGGCAAAAGCAAGGCCACAACCTACGGTAACTTTGGGGGTGAATAACACTCGTTCTCC
AGAGCAGCGTACGGAAAATCAAATCCGTTTAGGGGTGGAAATTCCTTTAAATCTTTTCAATCGTCAACAATACGGAATCA
AGATTGCTCAGGCCAAGCAAGAGCTGTCTCAACGCCAACAGAGCTTTTATCGACAGCAGAATCAAGCGGATATTGAAACT
CTGATGTCAGAGTTAAAAGGCTTACATATTCAGTTCAAGCAATTAAATGATCAGCAAGTTCCTCTTGCCGTTCAGGTTCA
ACAAAAAACATTGCAAGGTTTCCGTTTGGGTAAGTTTGCCGTTACCGATGTGCAGCAAGCCACAATGCAGTTGCAAGATG
TGCGCTTACGTAAAGTCGAGCTATTAAAACAGGCTTGGCAAAATTCAATTGAAATTCAAAGTTTACGTCTAGGGCTAGAG
CCAGAACAGATCATGGCGAAAGATGCCTTAATGCAACTTAATCAACGTGCTTGGCAACAAGCTCAAACTTTTCCAACTCA
GGCAGGAGAATAA

Upstream 100 bases:

>100_bases
GGTGAGCCATCCCGACTTATTGAGCTGTAACGTTAAGATAACGTTGAAAAAGGTTGTAACTATCTCAAGCCTGTCTATTG
TCATGTTATTGGCGGGACAA

Downstream 100 bases:

>100_bases
TAATGTCGGCAAATTTAAAGAAAAATTCTCAATGGCTTTGGGTTGGAGTAATTGCTGCCATTACTGCAATATTAATTGGT
TTACTCGTTTTAAATTCAAA

Product: cation efflux system protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MANAATDFQQGSYTQKAAFSFEQALARAQSYQIQQGVWQAQQQMAEAQLKQSRLWANPSLSIEQTGLQSDQEKELAIGIS
QPLDIFGQRKAAQHLAKVEMSKVDLAEQRYKAELELIVKYFWSQVALLELEKSLIGEQLAVSQENLSASEKRYQAGSIAQ
VDVDRVRMSHLENQRLYQQVDLKLQVAKQQLANLWGGDSNQFQLSQSSNQLWVLAADVESGQDRQNNLLERSFQLDALAQ
QATIQQLKAKARPQPTVTLGVNNTRSPEQRTENQIRLGVEIPLNLFNRQQYGIKIAQAKQELSQRQQSFYRQQNQADIET
LMSELKGLHIQFKQLNDQQVPLAVQVQQKTLQGFRLGKFAVTDVQQATMQLQDVRLRKVELLKQAWQNSIEIQSLRLGLE
PEQIMAKDALMQLNQRAWQQAQTFPTQAGE

Sequences:

>Translated_430_residues
MANAATDFQQGSYTQKAAFSFEQALARAQSYQIQQGVWQAQQQMAEAQLKQSRLWANPSLSIEQTGLQSDQEKELAIGIS
QPLDIFGQRKAAQHLAKVEMSKVDLAEQRYKAELELIVKYFWSQVALLELEKSLIGEQLAVSQENLSASEKRYQAGSIAQ
VDVDRVRMSHLENQRLYQQVDLKLQVAKQQLANLWGGDSNQFQLSQSSNQLWVLAADVESGQDRQNNLLERSFQLDALAQ
QATIQQLKAKARPQPTVTLGVNNTRSPEQRTENQIRLGVEIPLNLFNRQQYGIKIAQAKQELSQRQQSFYRQQNQADIET
LMSELKGLHIQFKQLNDQQVPLAVQVQQKTLQGFRLGKFAVTDVQQATMQLQDVRLRKVELLKQAWQNSIEIQSLRLGLE
PEQIMAKDALMQLNQRAWQQAQTFPTQAGE
>Mature_429_residues
ANAATDFQQGSYTQKAAFSFEQALARAQSYQIQQGVWQAQQQMAEAQLKQSRLWANPSLSIEQTGLQSDQEKELAIGISQ
PLDIFGQRKAAQHLAKVEMSKVDLAEQRYKAELELIVKYFWSQVALLELEKSLIGEQLAVSQENLSASEKRYQAGSIAQV
DVDRVRMSHLENQRLYQQVDLKLQVAKQQLANLWGGDSNQFQLSQSSNQLWVLAADVESGQDRQNNLLERSFQLDALAQQ
ATIQQLKAKARPQPTVTLGVNNTRSPEQRTENQIRLGVEIPLNLFNRQQYGIKIAQAKQELSQRQQSFYRQQNQADIETL
MSELKGLHIQFKQLNDQQVPLAVQVQQKTLQGFRLGKFAVTDVQQATMQLQDVRLRKVELLKQAWQNSIEIQSLRLGLEP
EQIMAKDALMQLNQRAWQQAQTFPTQAGE

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48974; Mature: 48843

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAATDFQQGSYTQKAAFSFEQALARAQSYQIQQGVWQAQQQMAEAQLKQSRLWANPSL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SIEQTGLQSDQEKELAIGISQPLDIFGQRKAAQHLAKVEMSKVDLAEQRYKAELELIVKY
CEECCCCCCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWSQVALLELEKSLIGEQLAVSQENLSASEKRYQAGSIAQVDVDRVRMSHLENQRLYQQV
HHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
DLKLQVAKQQLANLWGGDSNQFQLSQSSNQLWVLAADVESGQDRQNNLLERSFQLDALAQ
HHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
QATIQQLKAKARPQPTVTLGVNNTRSPEQRTENQIRLGVEIPLNLFNRQQYGIKIAQAKQ
HHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCEEEEEECCHHHHCCHHHCCHHHHHHH
ELSQRQQSFYRQQNQADIETLMSELKGLHIQFKQLNDQQVPLAVQVQQKTLQGFRLGKFA
HHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEHHHHHCCCCCCCHH
VTDVQQATMQLQDVRLRKVELLKQAWQNSIEIQSLRLGLEPEQIMAKDALMQLNQRAWQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AQTFPTQAGE
HHCCCCCCCC
>Mature Secondary Structure 
ANAATDFQQGSYTQKAAFSFEQALARAQSYQIQQGVWQAQQQMAEAQLKQSRLWANPSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SIEQTGLQSDQEKELAIGISQPLDIFGQRKAAQHLAKVEMSKVDLAEQRYKAELELIVKY
CEECCCCCCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWSQVALLELEKSLIGEQLAVSQENLSASEKRYQAGSIAQVDVDRVRMSHLENQRLYQQV
HHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
DLKLQVAKQQLANLWGGDSNQFQLSQSSNQLWVLAADVESGQDRQNNLLERSFQLDALAQ
HHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
QATIQQLKAKARPQPTVTLGVNNTRSPEQRTENQIRLGVEIPLNLFNRQQYGIKIAQAKQ
HHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCEEEEEECCHHHHCCHHHCCHHHHHHH
ELSQRQQSFYRQQNQADIETLMSELKGLHIQFKQLNDQQVPLAVQVQQKTLQGFRLGKFA
HHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEHHHHHCCCCCCCHH
VTDVQQATMQLQDVRLRKVELLKQAWQNSIEIQSLRLGLEPEQIMAKDALMQLNQRAWQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AQTFPTQAGE
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]