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The map label for this gene is czcD [H]

Identifier: 213158964

GI number: 213158964

Start: 3777638

End: 3778594

Strand: Reverse

Name: czcD [H]

Synonym: AB57_3665

Alternate gene names: 213158964

Gene position: 3778594-3777638 (Counterclockwise)

Preceding gene: 213158965

Following gene: 213158962

Centisome position: 93.29

GC content: 38.56

Gene sequence:

>957_bases
ATGGGTGGACATCATGGTCATGATCATAGTCATGCTGTAGTGACTGAGGGTAATGCTAAAAAATTAACGATTGCCTTGGC
GCTTACCACGACATTCTTAATTGTTGAGGTGATTGCAGGTTTAATCACACAAAGTTTGGCATTGCTCTCTGACGCTGCAC
ATATGTTTACAGATGCAGCTGCTTTAGCAATTGCTTTGGTTGCCATACAGATTTCTAAACGTCCTGCCGATAATAAACGT
ACTTTCGGTTATCAGCGCTTTGAAATTCTGGCCGCTTTATTTAATGCACTTATGCTTTTTGTGGTGGCAATTTATATTTT
ATATGAAGCCTATATCCGCTTTTCGCAGCCACCTGAAATTCAAAGTGTAGGTATGCTCATTGTGGCGACCATTGGTTTGG
TAATAAACCTCATCTCAATGAAAATTCTTATGTCGAGTGCTAATAACAGCTTAAATGTGAAAGGTGCTTATCTAGAAGTA
TTGAGTGATGCACTAGGCTCAGTTGGCGTTATTATTGGTGCAATTATTATTTACTTCACTAATTGGTATTGGATTGACAC
GCTTATTGCGGTACTGATTGGATTTTGGGTATTGCCAAGAACATGGGTTTTACTTAAACAAAGTATTAATATTTTGCTCG
AAGGTGTACCCGAAGAAGTCGATATTGAAAAGCTACGTGCAGATTTACTTTCATTAAATGGTGTGGAGAGTATTCACCAA
CTCAAAGTATGGGCAATTACCTCTAAAAATATCCATTTAACTGTACACTTATTTGCGCCTGAAGCTGACCGTAACAAGCT
CTATCAAGATGCAGTTGAAATGCTTTCTCATGAGCATGGTATTGGTGAAGTGACATTGCAAATTGAAGATGATGCTGAGA
TTAACTGTCAGCATATTGCTCAACATGCTTCACACGAGCATAACGATAATGACAAGACGCATTCACATCAGCATTAA

Upstream 100 bases:

>100_bases
AAAATTTAAGTCGAAAAAGTGTTTGTAAGAGTTAAAGGTAAAGGTGTCTTCATCGTTACTTTTAACTCACCATAAAGATA
AATAAAAAGGAGTCCGCAAA

Downstream 100 bases:

>100_bases
GCTGATGTGAATATAGGTTTAAATTTCCCACTCATGATTGCAGTCACGACATTTCCAATGTTTTTGTGACTGCATAAATG
CTTGCATAGACAATTTAAAA

Product: cation efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MGGHHGHDHSHAVVTEGNAKKLTIALALTTTFLIVEVIAGLITQSLALLSDAAHMFTDAAALAIALVAIQISKRPADNKR
TFGYQRFEILAALFNALMLFVVAIYILYEAYIRFSQPPEIQSVGMLIVATIGLVINLISMKILMSSANNSLNVKGAYLEV
LSDALGSVGVIIGAIIIYFTNWYWIDTLIAVLIGFWVLPRTWVLLKQSINILLEGVPEEVDIEKLRADLLSLNGVESIHQ
LKVWAITSKNIHLTVHLFAPEADRNKLYQDAVEMLSHEHGIGEVTLQIEDDAEINCQHIAQHASHEHNDNDKTHSHQH

Sequences:

>Translated_318_residues
MGGHHGHDHSHAVVTEGNAKKLTIALALTTTFLIVEVIAGLITQSLALLSDAAHMFTDAAALAIALVAIQISKRPADNKR
TFGYQRFEILAALFNALMLFVVAIYILYEAYIRFSQPPEIQSVGMLIVATIGLVINLISMKILMSSANNSLNVKGAYLEV
LSDALGSVGVIIGAIIIYFTNWYWIDTLIAVLIGFWVLPRTWVLLKQSINILLEGVPEEVDIEKLRADLLSLNGVESIHQ
LKVWAITSKNIHLTVHLFAPEADRNKLYQDAVEMLSHEHGIGEVTLQIEDDAEINCQHIAQHASHEHNDNDKTHSHQH
>Mature_317_residues
GGHHGHDHSHAVVTEGNAKKLTIALALTTTFLIVEVIAGLITQSLALLSDAAHMFTDAAALAIALVAIQISKRPADNKRT
FGYQRFEILAALFNALMLFVVAIYILYEAYIRFSQPPEIQSVGMLIVATIGLVINLISMKILMSSANNSLNVKGAYLEVL
SDALGSVGVIIGAIIIYFTNWYWIDTLIAVLIGFWVLPRTWVLLKQSINILLEGVPEEVDIEKLRADLLSLNGVESIHQL
KVWAITSKNIHLTVHLFAPEADRNKLYQDAVEMLSHEHGIGEVTLQIEDDAEINCQHIAQHASHEHNDNDKTHSHQH

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=315, Percent_Identity=34.2857142857143, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI21361112, Length=314, Percent_Identity=29.6178343949045, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI64762489, Length=315, Percent_Identity=30.4761904761905, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI289803013, Length=310, Percent_Identity=30.3225806451613, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI289803009, Length=310, Percent_Identity=30.3225806451613, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI289803007, Length=310, Percent_Identity=30.3225806451613, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI289803003, Length=310, Percent_Identity=30.3225806451613, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI21359890, Length=314, Percent_Identity=29.2993630573248, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI20070323, Length=344, Percent_Identity=24.7093023255814, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI14210520, Length=226, Percent_Identity=32.3008849557522, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI52351208, Length=155, Percent_Identity=35.4838709677419, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI222080086, Length=132, Percent_Identity=32.5757575757576, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI40255009, Length=132, Percent_Identity=32.5757575757576, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI52352803, Length=128, Percent_Identity=40.625, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1786966, Length=277, Percent_Identity=39.7111913357401, Blast_Score=160, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI193210990, Length=315, Percent_Identity=30.7936507936508, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17555794, Length=324, Percent_Identity=28.0864197530864, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32564488, Length=304, Percent_Identity=30.5921052631579, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17555796, Length=325, Percent_Identity=27.0769230769231, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17550442, Length=131, Percent_Identity=31.2977099236641, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17550440, Length=131, Percent_Identity=31.2977099236641, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323899, Length=137, Percent_Identity=35.7664233576642, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320411, Length=169, Percent_Identity=34.3195266272189, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324892, Length=122, Percent_Identity=37.7049180327869, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24583858, Length=329, Percent_Identity=27.6595744680851, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24585900, Length=127, Percent_Identity=39.3700787401575, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24585898, Length=127, Percent_Identity=39.3700787401575, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24585896, Length=127, Percent_Identity=39.3700787401575, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI19921672, Length=127, Percent_Identity=39.3700787401575, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24645863, Length=128, Percent_Identity=36.71875, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584409, Length=137, Percent_Identity=34.3065693430657, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28574430, Length=137, Percent_Identity=34.3065693430657, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24656728, Length=128, Percent_Identity=37.5, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24656724, Length=128, Percent_Identity=37.5, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24656720, Length=128, Percent_Identity=37.5, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24656715, Length=128, Percent_Identity=37.5, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357035, Length=128, Percent_Identity=37.5, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 35140; Mature: 35009

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGHHGHDHSHAVVTEGNAKKLTIALALTTTFLIVEVIAGLITQSLALLSDAAHMFTDAA
CCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIALVAIQISKRPADNKRTFGYQRFEILAALFNALMLFVVAIYILYEAYIRFSQPPEI
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
QSVGMLIVATIGLVINLISMKILMSSANNSLNVKGAYLEVLSDALGSVGVIIGAIIIYFT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
NWYWIDTLIAVLIGFWVLPRTWVLLKQSINILLEGVPEEVDIEKLRADLLSLNGVESIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHH
LKVWAITSKNIHLTVHLFAPEADRNKLYQDAVEMLSHEHGIGEVTLQIEDDAEINCQHIA
EEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
QHASHEHNDNDKTHSHQH
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GGHHGHDHSHAVVTEGNAKKLTIALALTTTFLIVEVIAGLITQSLALLSDAAHMFTDAA
CCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIALVAIQISKRPADNKRTFGYQRFEILAALFNALMLFVVAIYILYEAYIRFSQPPEI
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
QSVGMLIVATIGLVINLISMKILMSSANNSLNVKGAYLEVLSDALGSVGVIIGAIIIYFT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
NWYWIDTLIAVLIGFWVLPRTWVLLKQSINILLEGVPEEVDIEKLRADLLSLNGVESIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHH
LKVWAITSKNIHLTVHLFAPEADRNKLYQDAVEMLSHEHGIGEVTLQIEDDAEINCQHIA
EEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
QHASHEHNDNDKTHSHQH
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]