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The map label for this gene is mraY [H]

Identifier: 213158951

GI number: 213158951

Start: 3762192

End: 3763310

Strand: Reverse

Name: mraY [H]

Synonym: AB57_3652

Alternate gene names: 213158951

Gene position: 3763310-3762192 (Counterclockwise)

Preceding gene: 213158952

Following gene: 213158950

Centisome position: 92.91

GC content: 40.75

Gene sequence:

>1119_bases
ATGCTGTTATGGTTGTTTGAACAACTTGCGGGCTATCACAGTTCGTTTCAGGTTGTTCGTTATTTAACATTACGTTCTTT
ACTCAGTGTATTAACGTCACTGACCATTGGTTTGGTTCTCGGACCAATCATGATTCGTAAATTACAAGCGTTAAAATACG
GTCAGGCAGTAAGTTCGTTTGCTCCTGAAAATCATGCTAAGAAAATGGGTACACCGACCATGGGTGGGATTTTAATTCTG
CTCTCAATTGGTATTAGTACTTTATTGTGGGCTGATTTATCTAACCCTTATGTTTGGATTGTACTTGGTGTAATGGTTGT
GTTCGGTGCGGTTGGCTGGGCAGATGACTGGATTAAAATTCGCTATAAAGATAATGCAGGTCTACCTGCCCGTAAGAAGT
TTTTCTGGACTTCTGTCGCATCGCTCGGTGCTGGTATTGCGTTATATTTAATTGCTACCCAACAATCTAATGCAGAATAC
ACAGCAAATATGCTGGATTTATTGATTCCTTTCTTTAAGAATCTTTCAATTCCGCTTTCTATTGTTCCTTTAGGTTTAGC
ATTTATTGTATTTACCTATTTAGTAATTAATGGTGCCTCTAATGCGGTTAACCTAACTGATGGATTAGATGGTTTAGCCA
TTATGCCAGTAGTTATGGTAGCGACGGGCTTAGGCGTATTTGCTTATTTATCTGGTGATATTCGTTTTGCCAACTATTTG
CATATTCCTTATGTGAAATATACCTCTGAACTTGTGGTGATCTGTTCTGCCATGATTGGTGCAGGTTTGGCATTTCTTTG
GTATAACGCACATCCGGCGCAAGTCTTTATGGGTGATGTGGGCGCTTTAGCTCTAGGCGCAATGCTTGGAACCATTGCCG
TTATGGTTCGCCAAGAAATCGTATTCGCAATTATGGGCGGTGTTTTCGTTATGGAAGCGGTATCGGTATTCCTGCAAATC
GGCTCATTACGAATGCGGAATAAACGCGTATTCTTGATGGCACCTTTGCACCATCACTATGAAAAACAAGGCTGGAAAGA
AACCCAAGTGGTCATCCGTTTCTGGATTATTACGATTATGCTGGTTGTTTTAGGCCTAATGACCTTAAAATTGCGCTAG

Upstream 100 bases:

>100_bases
AATCCAAACACATCAACCCCAGTCCATGAGTTTCCTGTTTAAAGGTTCTCGCTTTACTCATATGGAAACGTTGATGGCTG
ATTTGATGGAGAAACTTTAA

Downstream 100 bases:

>100_bases
AACTTATTTTGGTGTCAATATAAAGCCAGTTTCTACTGGCTTTTTTTATTGGAGAGGTAAATGACAAAAGTTGCTGGTCT
AGACCAATTATCTGTAATTA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLLWLFEQLAGYHSSFQVVRYLTLRSLLSVLTSLTIGLVLGPIMIRKLQALKYGQAVSSFAPENHAKKMGTPTMGGILIL
LSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKIRYKDNAGLPARKKFFWTSVASLGAGIALYLIATQQSNAEY
TANMLDLLIPFFKNLSIPLSIVPLGLAFIVFTYLVINGASNAVNLTDGLDGLAIMPVVMVATGLGVFAYLSGDIRFANYL
HIPYVKYTSELVVICSAMIGAGLAFLWYNAHPAQVFMGDVGALALGAMLGTIAVMVRQEIVFAIMGGVFVMEAVSVFLQI
GSLRMRNKRVFLMAPLHHHYEKQGWKETQVVIRFWIITIMLVVLGLMTLKLR

Sequences:

>Translated_372_residues
MLLWLFEQLAGYHSSFQVVRYLTLRSLLSVLTSLTIGLVLGPIMIRKLQALKYGQAVSSFAPENHAKKMGTPTMGGILIL
LSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKIRYKDNAGLPARKKFFWTSVASLGAGIALYLIATQQSNAEY
TANMLDLLIPFFKNLSIPLSIVPLGLAFIVFTYLVINGASNAVNLTDGLDGLAIMPVVMVATGLGVFAYLSGDIRFANYL
HIPYVKYTSELVVICSAMIGAGLAFLWYNAHPAQVFMGDVGALALGAMLGTIAVMVRQEIVFAIMGGVFVMEAVSVFLQI
GSLRMRNKRVFLMAPLHHHYEKQGWKETQVVIRFWIITIMLVVLGLMTLKLR
>Mature_372_residues
MLLWLFEQLAGYHSSFQVVRYLTLRSLLSVLTSLTIGLVLGPIMIRKLQALKYGQAVSSFAPENHAKKMGTPTMGGILIL
LSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKIRYKDNAGLPARKKFFWTSVASLGAGIALYLIATQQSNAEY
TANMLDLLIPFFKNLSIPLSIVPLGLAFIVFTYLVINGASNAVNLTDGLDGLAIMPVVMVATGLGVFAYLSGDIRFANYL
HIPYVKYTSELVVICSAMIGAGLAFLWYNAHPAQVFMGDVGALALGAMLGTIAVMVRQEIVFAIMGGVFVMEAVSVFLQI
GSLRMRNKRVFLMAPLHHHYEKQGWKETQVVIRFWIITIMLVVLGLMTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=373, Percent_Identity=54.9597855227882, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40916; Mature: 40916

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLWLFEQLAGYHSSFQVVRYLTLRSLLSVLTSLTIGLVLGPIMIRKLQALKYGQAVSSF
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APENHAKKMGTPTMGGILILLSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKI
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
RYKDNAGLPARKKFFWTSVASLGAGIALYLIATQQSNAEYTANMLDLLIPFFKNLSIPLS
EEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHH
IVPLGLAFIVFTYLVINGASNAVNLTDGLDGLAIMPVVMVATGLGVFAYLSGDIRFANYL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
HIPYVKYTSELVVICSAMIGAGLAFLWYNAHPAQVFMGDVGALALGAMLGTIAVMVRQEI
ECCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAIMGGVFVMEAVSVFLQIGSLRMRNKRVFLMAPLHHHYEKQGWKETQVVIRFWIITIM
HHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHH
LVVLGLMTLKLR
HHHHHHHHHCCC
>Mature Secondary Structure
MLLWLFEQLAGYHSSFQVVRYLTLRSLLSVLTSLTIGLVLGPIMIRKLQALKYGQAVSSF
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APENHAKKMGTPTMGGILILLSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKI
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
RYKDNAGLPARKKFFWTSVASLGAGIALYLIATQQSNAEYTANMLDLLIPFFKNLSIPLS
EEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHH
IVPLGLAFIVFTYLVINGASNAVNLTDGLDGLAIMPVVMVATGLGVFAYLSGDIRFANYL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
HIPYVKYTSELVVICSAMIGAGLAFLWYNAHPAQVFMGDVGALALGAMLGTIAVMVRQEI
ECCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAIMGGVFVMEAVSVFLQIGSLRMRNKRVFLMAPLHHHYEKQGWKETQVVIRFWIITIM
HHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHH
LVVLGLMTLKLR
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA