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The map label for this gene is proA [H]

Identifier: 213158881

GI number: 213158881

Start: 3685930

End: 3687285

Strand: Reverse

Name: proA [H]

Synonym: AB57_3580

Alternate gene names: 213158881

Gene position: 3687285-3685930 (Counterclockwise)

Preceding gene: 213158882

Following gene: 213158877

Centisome position: 91.03

GC content: 43.44

Gene sequence:

>1356_bases
ATGCAAAGTAAAACGTTGTTTCTATTAGGTCTATGTACAATTTTCAGTACAACTGTGTCCGCTCTTCCTTTGGATTACAA
AGGGGCCAAACAGCGGTTAAGTCAGGCAGCAAAACAAAAAGTGTTCCAAGGTAAAATAGATTTAGATGCCTTGGTTAGTA
ATGATTCAAACGATTTAATTGTCGAATACAATATTCCTTCATCGAGCGTACCTTCCGGTTTAGAACGGCGAAGTTATATT
GCTACAAATAAAAAGAATCTTCAGACAAGGTTTAATCGTGCCGGCGGTGTACAAGTACTTCGGGATTACAATAACCTACC
TTTGGCTTTTTATCGGATTAGTAACCGTGAGGCTTTAGTATCTTTATTAAATGATCCGAACGTTAAAGCAGTTTATCCAA
ACCGTATTAACCGTACTACAACTACTGAAAGTTTGCCTTTGATTAATCAACCACAAGCCAATACCAATGGTTTTACGGGG
GAGGGATCTAGTGTTGCTGTGCTGGATACAGGGGTAAATTATCTACATTCAGATTTTGGATGTACCGCTGTGAATACTCC
ATCGAGTACTTGCCGCGTGGTTTATTCTTTTGATAGTGCACCAGATGATGGCACTTTGGATGATGATGGGCATGGCAGTA
ACGTTTCCGCTATTGTGTCGAAAGTCGCCACTAAAACTAAAATTATTGGTATTGATGTATTTAGAAAGGTCAGATCGCAA
GGTAAGTGGGTAAGCACCGCTTATGATAGTGATATTCTCGCGGGGATTAACTGGGCTGTAAACAATGCACAAACCTATAA
TATTAAAGCGGTGAATTTGAGCCTTGGTGTGCCGGGAGTCAAATATACCTCTGAGTGTAGCGATAGCAGTTATGGAACAG
CATTTGCCAATGCGCGAGCTGCTGGCGTGGTTCCGGTTGTAGCCTCTGGTAATGATGCCTTCCCTGACGGAATTTCATCT
CCTGCTTGTGTGGCAGGGGCAGTAAGGGTAGGTGCTGTTTATGATAGTAATATTGGTGGTGTGTCATGGGGTAACCCCGT
GAAATGTTCTGACCCTACTACAGCAGCAGATAAGGTAGCCTGCTTTAGTAATGGGGGAAGCCTTGTGACTTTATTGGCGC
CGGGTGCAATGATTACCGCAGGTGGCTATACCATGGGCGGTACCTCTCAAGCGACACCACATGTGGCAGGCGCGATTGCT
CTATTGAGAGCGAATAGTGTGAGTCCAACTGAAAGTATCGATCAAACCATTAGTCGGTTAAAAGCTACGGGTAAACCTAT
TACTGACTCAAGAACGGGCTTGGTTTTCCCACGGATTGATTTACTGGCGGCAACCAATGGTTTAACCGTTAACTAA

Upstream 100 bases:

>100_bases
GTGATCCTTCGATTCAACCGATTGATCCAGAAAAAGATCCAGCAAATGAAATAAAAGCGAAATAAGCAAATTGTTAGTTG
AAAAACTACGGAGAAAAATA

Downstream 100 bases:

>100_bases
ATAGCATATTTATAATTTTTATTAGGTCCAAAAAATTTAAATGGCTATGGCTCGTTGCAAAAGATAACTTCTGCAACGAG
TTTTTTTATGAAAAAGCCTT

Product: peptidase S8/S53 subtilisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQSKTLFLLGLCTIFSTTVSALPLDYKGAKQRLSQAAKQKVFQGKIDLDALVSNDSNDLIVEYNIPSSSVPSGLERRSYI
ATNKKNLQTRFNRAGGVQVLRDYNNLPLAFYRISNREALVSLLNDPNVKAVYPNRINRTTTTESLPLINQPQANTNGFTG
EGSSVAVLDTGVNYLHSDFGCTAVNTPSSTCRVVYSFDSAPDDGTLDDDGHGSNVSAIVSKVATKTKIIGIDVFRKVRSQ
GKWVSTAYDSDILAGINWAVNNAQTYNIKAVNLSLGVPGVKYTSECSDSSYGTAFANARAAGVVPVVASGNDAFPDGISS
PACVAGAVRVGAVYDSNIGGVSWGNPVKCSDPTTAADKVACFSNGGSLVTLLAPGAMITAGGYTMGGTSQATPHVAGAIA
LLRANSVSPTESIDQTISRLKATGKPITDSRTGLVFPRIDLLAATNGLTVN

Sequences:

>Translated_451_residues
MQSKTLFLLGLCTIFSTTVSALPLDYKGAKQRLSQAAKQKVFQGKIDLDALVSNDSNDLIVEYNIPSSSVPSGLERRSYI
ATNKKNLQTRFNRAGGVQVLRDYNNLPLAFYRISNREALVSLLNDPNVKAVYPNRINRTTTTESLPLINQPQANTNGFTG
EGSSVAVLDTGVNYLHSDFGCTAVNTPSSTCRVVYSFDSAPDDGTLDDDGHGSNVSAIVSKVATKTKIIGIDVFRKVRSQ
GKWVSTAYDSDILAGINWAVNNAQTYNIKAVNLSLGVPGVKYTSECSDSSYGTAFANARAAGVVPVVASGNDAFPDGISS
PACVAGAVRVGAVYDSNIGGVSWGNPVKCSDPTTAADKVACFSNGGSLVTLLAPGAMITAGGYTMGGTSQATPHVAGAIA
LLRANSVSPTESIDQTISRLKATGKPITDSRTGLVFPRIDLLAATNGLTVN
>Mature_451_residues
MQSKTLFLLGLCTIFSTTVSALPLDYKGAKQRLSQAAKQKVFQGKIDLDALVSNDSNDLIVEYNIPSSSVPSGLERRSYI
ATNKKNLQTRFNRAGGVQVLRDYNNLPLAFYRISNREALVSLLNDPNVKAVYPNRINRTTTTESLPLINQPQANTNGFTG
EGSSVAVLDTGVNYLHSDFGCTAVNTPSSTCRVVYSFDSAPDDGTLDDDGHGSNVSAIVSKVATKTKIIGIDVFRKVRSQ
GKWVSTAYDSDILAGINWAVNNAQTYNIKAVNLSLGVPGVKYTSECSDSSYGTAFANARAAGVVPVVASGNDAFPDGISS
PACVAGAVRVGAVYDSNIGGVSWGNPVKCSDPTTAADKVACFSNGGSLVTLLAPGAMITAGGYTMGGTSQATPHVAGAIA
LLRANSVSPTESIDQTISRLKATGKPITDSRTGLVFPRIDLLAATNGLTVN

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324576, Length=352, Percent_Identity=24.7159090909091, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 47282; Mature: 47282

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKTLFLLGLCTIFSTTVSALPLDYKGAKQRLSQAAKQKVFQGKIDLDALVSNDSNDLI
CCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEE
VEYNIPSSSVPSGLERRSYIATNKKNLQTRFNRAGGVQVLRDYNNLPLAFYRISNREALV
EEECCCCCCCCCCHHHHHHECCCCHHHHHHHCCCCCEEEEECCCCCCEEEEEECCHHHHH
SLLNDPNVKAVYPNRINRTTTTESLPLINQPQANTNGFTGEGSSVAVLDTGVNYLHSDFG
HHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCC
CTAVNTPSSTCRVVYSFDSAPDDGTLDDDGHGSNVSAIVSKVATKTKIIGIDVFRKVRSQ
CEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEHHHHHHHHHC
GKWVSTAYDSDILAGINWAVNNAQTYNIKAVNLSLGVPGVKYTSECSDSSYGTAFANARA
CCEEEECCCCCHHCCCEEEECCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AGVVPVVASGNDAFPDGISSPACVAGAVRVGAVYDSNIGGVSWGNPVKCSDPTTAADKVA
CCEEEEEECCCCCCCCCCCCCHHHHHHEEEEEEEECCCCCCCCCCCEECCCCCCCHHCEE
CFSNGGSLVTLLAPGAMITAGGYTMGGTSQATPHVAGAIALLRANSVSPTESIDQTISRL
EECCCCCEEEEEECCEEEEECCEEECCCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHHH
KATGKPITDSRTGLVFPRIDLLAATNGLTVN
HHCCCCCCCCCCEEEECCEEEEEECCCCEEC
>Mature Secondary Structure
MQSKTLFLLGLCTIFSTTVSALPLDYKGAKQRLSQAAKQKVFQGKIDLDALVSNDSNDLI
CCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEE
VEYNIPSSSVPSGLERRSYIATNKKNLQTRFNRAGGVQVLRDYNNLPLAFYRISNREALV
EEECCCCCCCCCCHHHHHHECCCCHHHHHHHCCCCCEEEEECCCCCCEEEEEECCHHHHH
SLLNDPNVKAVYPNRINRTTTTESLPLINQPQANTNGFTGEGSSVAVLDTGVNYLHSDFG
HHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCC
CTAVNTPSSTCRVVYSFDSAPDDGTLDDDGHGSNVSAIVSKVATKTKIIGIDVFRKVRSQ
CEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEHHHHHHHHHC
GKWVSTAYDSDILAGINWAVNNAQTYNIKAVNLSLGVPGVKYTSECSDSSYGTAFANARA
CCEEEECCCCCHHCCCEEEECCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AGVVPVVASGNDAFPDGISSPACVAGAVRVGAVYDSNIGGVSWGNPVKCSDPTTAADKVA
CCEEEEEECCCCCCCCCCCCCHHHHHHEEEEEEEECCCCCCCCCCCEECCCCCCCHHCEE
CFSNGGSLVTLLAPGAMITAGGYTMGGTSQATPHVAGAIALLRANSVSPTESIDQTISRL
EECCCCCEEEEEECCEEEEECCEEECCCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHHH
KATGKPITDSRTGLVFPRIDLLAATNGLTVN
HHCCCCCCCCCCEEEECCEEEEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2546861 [H]