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The map label for this gene is secY [H]

Identifier: 213158815

GI number: 213158815

Start: 3625415

End: 3626773

Strand: Reverse

Name: secY [H]

Synonym: AB57_3510

Alternate gene names: 213158815

Gene position: 3626773-3625415 (Counterclockwise)

Preceding gene: 213158816

Following gene: 213158814

Centisome position: 89.54

GC content: 38.93

Gene sequence:

>1359_bases
GTGTCTATGTCTCCTAGTTCTTCAGGTCATGTCAACATGATGAAAGGTCAGCCATTTCACGTGAAATATCGTGAAATTAT
TCGCCGGATGAGTTTTCTAATCGGTGCATTGCTGGTCTTTCGACTAGGAGCGCATATTCCAGTACCAGGCATTAATAATG
CTGCGTTAGAAAATTTATTTCATGCAAACCAAGGAACTATTCTTGGGCTATTCAATATGTTTTCTGGCGGTGCTTTAGAG
CGAATGTCGATTCTTGCTTTAGGAATCATGCCTTATATTTCTGCATCAATTATTGTGCAGTTAATGTCTACAGTGATTCC
TTCTCTCGAAGCCTTGAAAAAGGAAGGGGAGCAAGGTAAACGTAAAATTAATCAATATACGCGTCAGGGTACATTATTAC
TTGCAGTGGTTCAGGCAGTAGGTATGTGTGCAGGTCTTATTGGACAGGGTATTACTCTATCTAGTGGTCTTGCTTTTTAT
ATACCTGCAGTTACATCACTTGTCGCAGGAACTATGTTCTTAATGTGGCTAGGTGAACAGATCACTGAAAGAGGTATCGG
TAATGGTATCTCAATGATTATTTTTGCAGGTATTGTTGCTGGTTTGCCTAAATTAATTATGCAATCAGTATCATCTGTCG
ATAATGGTCAAACAAGTTTAATTGGTCTTGTTATCTTTGGTCTTTTGTCTCTTGGTGTATTGGCAGCGATTGTGTTTATT
GAAAAAGCACAGTGTCGTATTCCAGTAAACTATGCCCAGAAGCAGCAAGGGCGTCGTATATTTACAGCTCAGCAAACACA
TCTACCGTTGAAAATTAATATGGCTGGTGTGATTCCTGCGATTTTTGCGAGTTCTTTACTCTTGTTCCCAGCTAGTTTGG
GACAATGGGTAGGAAGTGCAGATCCGAATGCTGGTTTAATTAAACGTAGTTTACAAGATTTAGCTTTAGTATTGTCGCCT
GGACAGCCTTTGTATTTGGTGCTCTTTGGTGCGTTAATTATCTTTTTCTGTTACTTTTATACGGCTTTAGTATTTAGCCC
TAAGGAAGTATCAGAAAATCTAAAACGCAGCGGAGCTTATGTGCCTGGTATTCGCCCAGGTGAGCAAACTGCTCGTTACT
TAGATCATATTCTTAATCGTTTGACGTTTATTGGTGCGATTTATATTACAGTCATTTGTTTGATGCCAATGATTCTACAA
AGTTCTTTTGGTATTCCATTCTATTTGGGTGGTACCTCATTACTCATTGTAGTCGTTGTTGTTATGGACTTTATGGCTCA
GCTACAAGCGCATTTAACTTCTCATCAATATGACAATCAAACATTAATGAGAAAAACGACTGCTCATCCTAAGGGATAA

Upstream 100 bases:

>100_bases
TGAAATCACTCGTGCATTCACTGTTCAAGGTGTTGCATTGACTAAAGGCGCTAAAGCTGCAATTGAAGCAGCTGGCGGCA
AAGTCGAGGAGTAATCTCGA

Downstream 100 bases:

>100_bases
GCGCACTTAGAGGTTTCATCATGAAAGTACAAGCTTCTGTAAAGAAAATTTGTGGTAGCTGTAAAGTTATCCGTCGTAAT
GGGGTTATTCGCGTGATTTG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSMSPSSSGHVNMMKGQPFHVKYREIIRRMSFLIGALLVFRLGAHIPVPGINNAALENLFHANQGTILGLFNMFSGGALE
RMSILALGIMPYISASIIVQLMSTVIPSLEALKKEGEQGKRKINQYTRQGTLLLAVVQAVGMCAGLIGQGITLSSGLAFY
IPAVTSLVAGTMFLMWLGEQITERGIGNGISMIIFAGIVAGLPKLIMQSVSSVDNGQTSLIGLVIFGLLSLGVLAAIVFI
EKAQCRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWVGSADPNAGLIKRSLQDLALVLSP
GQPLYLVLFGALIIFFCYFYTALVFSPKEVSENLKRSGAYVPGIRPGEQTARYLDHILNRLTFIGAIYITVICLMPMILQ
SSFGIPFYLGGTSLLIVVVVVMDFMAQLQAHLTSHQYDNQTLMRKTTAHPKG

Sequences:

>Translated_452_residues
MSMSPSSSGHVNMMKGQPFHVKYREIIRRMSFLIGALLVFRLGAHIPVPGINNAALENLFHANQGTILGLFNMFSGGALE
RMSILALGIMPYISASIIVQLMSTVIPSLEALKKEGEQGKRKINQYTRQGTLLLAVVQAVGMCAGLIGQGITLSSGLAFY
IPAVTSLVAGTMFLMWLGEQITERGIGNGISMIIFAGIVAGLPKLIMQSVSSVDNGQTSLIGLVIFGLLSLGVLAAIVFI
EKAQCRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWVGSADPNAGLIKRSLQDLALVLSP
GQPLYLVLFGALIIFFCYFYTALVFSPKEVSENLKRSGAYVPGIRPGEQTARYLDHILNRLTFIGAIYITVICLMPMILQ
SSFGIPFYLGGTSLLIVVVVVMDFMAQLQAHLTSHQYDNQTLMRKTTAHPKG
>Mature_451_residues
SMSPSSSGHVNMMKGQPFHVKYREIIRRMSFLIGALLVFRLGAHIPVPGINNAALENLFHANQGTILGLFNMFSGGALER
MSILALGIMPYISASIIVQLMSTVIPSLEALKKEGEQGKRKINQYTRQGTLLLAVVQAVGMCAGLIGQGITLSSGLAFYI
PAVTSLVAGTMFLMWLGEQITERGIGNGISMIIFAGIVAGLPKLIMQSVSSVDNGQTSLIGLVIFGLLSLGVLAAIVFIE
KAQCRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWVGSADPNAGLIKRSLQDLALVLSPG
QPLYLVLFGALIIFFCYFYTALVFSPKEVSENLKRSGAYVPGIRPGEQTARYLDHILNRLTFIGAIYITVICLMPMILQS
SFGIPFYLGGTSLLIVVVVVMDFMAQLQAHLTSHQYDNQTLMRKTTAHPKG

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=419, Percent_Identity=58.7112171837709, Blast_Score=474, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48920; Mature: 48789

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS00755 SECY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSPSSSGHVNMMKGQPFHVKYREIIRRMSFLIGALLVFRLGAHIPVPGINNAALENLF
CCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
HANQGTILGLFNMFSGGALERMSILALGIMPYISASIIVQLMSTVIPSLEALKKEGEQGK
HCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKINQYTRQGTLLLAVVQAVGMCAGLIGQGITLSSGLAFYIPAVTSLVAGTMFLMWLGEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ITERGIGNGISMIIFAGIVAGLPKLIMQSVSSVDNGQTSLIGLVIFGLLSLGVLAAIVFI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKAQCRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWVGSA
HHCCCCCCCCHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPNAGLIKRSLQDLALVLSPGQPLYLVLFGALIIFFCYFYTALVFSPKEVSENLKRSGAY
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
VPGIRPGEQTARYLDHILNRLTFIGAIYITVICLMPMILQSSFGIPFYLGGTSLLIVVVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHH
VMDFMAQLQAHLTSHQYDNQTLMRKTTAHPKG
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SMSPSSSGHVNMMKGQPFHVKYREIIRRMSFLIGALLVFRLGAHIPVPGINNAALENLF
CCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
HANQGTILGLFNMFSGGALERMSILALGIMPYISASIIVQLMSTVIPSLEALKKEGEQGK
HCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKINQYTRQGTLLLAVVQAVGMCAGLIGQGITLSSGLAFYIPAVTSLVAGTMFLMWLGEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ITERGIGNGISMIIFAGIVAGLPKLIMQSVSSVDNGQTSLIGLVIFGLLSLGVLAAIVFI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKAQCRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWVGSA
HHCCCCCCCCHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPNAGLIKRSLQDLALVLSPGQPLYLVLFGALIIFFCYFYTALVFSPKEVSENLKRSGAY
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
VPGIRPGEQTARYLDHILNRLTFIGAIYITVICLMPMILQSSFGIPFYLGGTSLLIVVVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHH
VMDFMAQLQAHLTSHQYDNQTLMRKTTAHPKG
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]