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The map label for this gene is tag [H]

Identifier: 213158756

GI number: 213158756

Start: 4012938

End: 4013498

Strand: Direct

Name: tag [H]

Synonym: AB57_3890

Alternate gene names: 213158756

Gene position: 4012938-4013498 (Clockwise)

Preceding gene: 213158755

Following gene: 213158757

Centisome position: 99.07

GC content: 41.35

Gene sequence:

>561_bases
ATGAAAACTCAACGCTGCGGATGGTGTTCCGATGATCCACTCTATATTGCTTATCATGATGAGGAATGGGGCAAACCAGA
ACACGACGAAGCCCGATTATTTGAAATGCTCTGTCTTGAAGGACAACAAGCAGGTCTATCTTGGATTACCGTACTGAAAA
AAAGAGAAAGCTACCGCCAGCACTTTTTTAATCATCCTATTGCTGACATTGCTGCATTTACGGATGACTTTTTAGAAACA
AAACTATCCGATGCAAGCTTAATTCGTCACTTAGGCAAACTCAAAGCTATTCGTGATAATGCGATTGCTTGGCAAGCCCT
TAAAGCCCAAGTTGGTGATGTTTCTAAATGGCTTTGGCAGTTTGTAGATGCCACTCCTCAACACAATGATGTTGTAGATT
ATCGCAACGCCCCTGCTCAAACTGAGCTCAGCCTAAAACTTTCCAAAACGCTTAAAAAAAATGGTTTCAAATTTGTTGGT
CCAACCACCTGCTATGCGTTTATGCAGGCAGTGGGTATGGTCAATGACCATGAAAATGATTGTCAATTTAAAGCTTCCTA
A

Upstream 100 bases:

>100_bases
AGACTTAACTCAAGCTGAACTGTATTATTGGGATACTCGCCCAAATGAATGGGTACCATTCAAACTCTAAAATACCAAGA
TAAATATAAGGAGCATCATC

Downstream 100 bases:

>100_bases
CCCACCAGAACGGTTCAAATCCGCTTAAGGAGTTTCCGATGAGCAATAATACGATTCAGGCTTATGCTGCAATGCAGGCA
GGTGAAAAACTGGTCCCATA

Product: DNA-3-methyladenine glycosylase 1

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosidase; TAG [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKTQRCGWCSDDPLYIAYHDEEWGKPEHDEARLFEMLCLEGQQAGLSWITVLKKRESYRQHFFNHPIADIAAFTDDFLET
KLSDASLIRHLGKLKAIRDNAIAWQALKAQVGDVSKWLWQFVDATPQHNDVVDYRNAPAQTELSLKLSKTLKKNGFKFVG
PTTCYAFMQAVGMVNDHENDCQFKAS

Sequences:

>Translated_186_residues
MKTQRCGWCSDDPLYIAYHDEEWGKPEHDEARLFEMLCLEGQQAGLSWITVLKKRESYRQHFFNHPIADIAAFTDDFLET
KLSDASLIRHLGKLKAIRDNAIAWQALKAQVGDVSKWLWQFVDATPQHNDVVDYRNAPAQTELSLKLSKTLKKNGFKFVG
PTTCYAFMQAVGMVNDHENDCQFKAS
>Mature_186_residues
MKTQRCGWCSDDPLYIAYHDEEWGKPEHDEARLFEMLCLEGQQAGLSWITVLKKRESYRQHFFNHPIADIAAFTDDFLET
KLSDASLIRHLGKLKAIRDNAIAWQALKAQVGDVSKWLWQFVDATPQHNDVVDYRNAPAQTELSLKLSKTLKKNGFKFVG
PTTCYAFMQAVGMVNDHENDCQFKAS

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=178, Percent_Identity=52.8089887640449, Blast_Score=194, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21342; Mature: 21342

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQRCGWCSDDPLYIAYHDEEWGKPEHDEARLFEMLCLEGQQAGLSWITVLKKRESYRQ
CCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
HFFNHPIADIAAFTDDFLETKLSDASLIRHLGKLKAIRDNAIAWQALKAQVGDVSKWLWQ
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDATPQHNDVVDYRNAPAQTELSLKLSKTLKKNGFKFVGPTTCYAFMQAVGMVNDHEND
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCCCC
CQFKAS
CEEECC
>Mature Secondary Structure
MKTQRCGWCSDDPLYIAYHDEEWGKPEHDEARLFEMLCLEGQQAGLSWITVLKKRESYRQ
CCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
HFFNHPIADIAAFTDDFLETKLSDASLIRHLGKLKAIRDNAIAWQALKAQVGDVSKWLWQ
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDATPQHNDVVDYRNAPAQTELSLKLSKTLKKNGFKFVGPTTCYAFMQAVGMVNDHEND
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCCCC
CQFKAS
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]