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The map label for this gene is lytH [H]

Identifier: 213158754

GI number: 213158754

Start: 4012116

End: 4012652

Strand: Direct

Name: lytH [H]

Synonym: AB57_3888

Alternate gene names: 213158754

Gene position: 4012116-4012652 (Clockwise)

Preceding gene: 213158753

Following gene: 213158755

Centisome position: 99.05

GC content: 45.44

Gene sequence:

>537_bases
GTGCGACGTTTTGTTTCCCATCTCTCACTTGGTTTTCTCATTATTCTATTGGCAGCCTGTGCCAGTGCACCTAAAAAACC
TGCCCCGCTTTCACCAGCTCAAGTTAGCAAACTCAAGAGTATGCAGCTTCCAAGTCGGCTTCCTGTTCCGGTAAAAGGTG
TCGATCGAGATGAGTTAAAAGACACATGGGGAGCTGCTCGGAGTCAGGGCCGTAGCCACGAAGGAATTGATATTTTGGCT
CCACGTGGAACCAAAGTGTACAGTGCAACTGAAGGGCTCATTGCCGATCTTCGTAATAATAACCTCGGTGGCAAAGTCAT
CTGGATTTTAGGCCCGGCAGGAACATGGCATTATTATGCTCATCTTGATGGACATAAACGTGGCTTAAACGTAGGTGACT
ATGTCAAAAAAGGTGATTTAATTGGCTATGTCGGCAACACGGGCAATGCACGTTATACTTCACCTCATCTTCATTATGGT
CTTTACTTAGATGGTAAAGGTCGTGGTGCTGTTAATCCTTATTCATATTTACGCTAG

Upstream 100 bases:

>100_bases
CTAAAGGTGTCCCAACTGCTATGAAAAAATTGATCTCGACAAGCCGTTCATGACATAGTGAGCAAAATAATTTTGATATG
GCTGTGACAGGGAGTATTTT

Downstream 100 bases:

>100_bases
GAACATTTTATGTCGGAAGCGCTGATCAATCGCTTAGTAGAGTTTGCCGAGTCTGGCAACCAGCAAAAGATCATTTTAAA
TGGCAATAGCTATCAAGGCT

Product: peptidase

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRRFVSHLSLGFLIILLAACASAPKKPAPLSPAQVSKLKSMQLPSRLPVPVKGVDRDELKDTWGAARSQGRSHEGIDILA
PRGTKVYSATEGLIADLRNNNLGGKVIWILGPAGTWHYYAHLDGHKRGLNVGDYVKKGDLIGYVGNTGNARYTSPHLHYG
LYLDGKGRGAVNPYSYLR

Sequences:

>Translated_178_residues
MRRFVSHLSLGFLIILLAACASAPKKPAPLSPAQVSKLKSMQLPSRLPVPVKGVDRDELKDTWGAARSQGRSHEGIDILA
PRGTKVYSATEGLIADLRNNNLGGKVIWILGPAGTWHYYAHLDGHKRGLNVGDYVKKGDLIGYVGNTGNARYTSPHLHYG
LYLDGKGRGAVNPYSYLR
>Mature_178_residues
MRRFVSHLSLGFLIILLAACASAPKKPAPLSPAQVSKLKSMQLPSRLPVPVKGVDRDELKDTWGAARSQGRSHEGIDILA
PRGTKVYSATEGLIADLRNNNLGGKVIWILGPAGTWHYYAHLDGHKRGLNVGDYVKKGDLIGYVGNTGNARYTSPHLHYG
LYLDGKGRGAVNPYSYLR

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 19374; Mature: 19374

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFVSHLSLGFLIILLAACASAPKKPAPLSPAQVSKLKSMQLPSRLPVPVKGVDRDELK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
DTWGAARSQGRSHEGIDILAPRGTKVYSATEGLIADLRNNNLGGKVIWILGPAGTWHYYA
HHHHHHHHCCCCCCCEEEECCCCCEEEECHHHHHHHHCCCCCCCEEEEEEECCCCEEEEE
HLDGHKRGLNVGDYVKKGDLIGYVGNTGNARYTSPHLHYGLYLDGKGRGAVNPYSYLR
EECCCCCCCCHHHHHCCCCEEEEECCCCCCEEECCCEEEEEEECCCCCCCCCCHHHCC
>Mature Secondary Structure
MRRFVSHLSLGFLIILLAACASAPKKPAPLSPAQVSKLKSMQLPSRLPVPVKGVDRDELK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
DTWGAARSQGRSHEGIDILAPRGTKVYSATEGLIADLRNNNLGGKVIWILGPAGTWHYYA
HHHHHHHHCCCCCCCEEEECCCCCEEEECHHHHHHHHCCCCCCCEEEEEEECCCCEEEEE
HLDGHKRGLNVGDYVKKGDLIGYVGNTGNARYTSPHLHYGLYLDGKGRGAVNPYSYLR
EECCCCCCCCHHHHHCCCCEEEEECCCCCCEEECCCEEEEEEECCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]