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The map label for this gene is exoX [H]

Identifier: 213158710

GI number: 213158710

Start: 2757726

End: 2758430

Strand: Direct

Name: exoX [H]

Synonym: AB57_2668

Alternate gene names: 213158710

Gene position: 2757726-2758430 (Clockwise)

Preceding gene: 213158708

Following gene: 213158711

Centisome position: 68.08

GC content: 38.72

Gene sequence:

>705_bases
TTGTTTAAAGGGCCGGATATGCAAGCCATTATTTTAGATACAGAAACACATACACTAAATGGTTTGCCTATTGAAATTGC
ATATGCCCCAATTGAAATTAATGCAGGCAAGCTCACCTTAGATAAAAGCAAATTGTTTGATCAACTTTATCAAGTTGGGA
CCCCTATCTCTTACGCGGCTATGGCAGTACACCATATATTAGAATCGGATTTAGAAAATCAGCCCCACTATAAAACTTTT
AAATTGCCAGACACTACAACTTATATTATTGGCCACAATATTGATTATGATATTGCCGCGATTGCGCGTTGCGGTGTAGA
TGTTTCTCATATCAAACCAATTTGTACGCTAGCTTTAGCACGTAAAACCTGGCCTGATGCAGAAGCGCATAATATCTCAG
CACTGATCTATATGATTTCTCAAGGCAGCAGTAAAGCTCGTGAATTACTCAAAGGCGCGCACCGTGCCGATGCGGATATT
ATTTTAACTGCCAATATCTTGATGCATATTGTCTATCATTTAAATATTCATGACATTGAAGAGTTGTACCGTGTTTCTGA
AGAAGCACGTATTCCCACAACAATTAACTTTGGCAAGCATAAAGGTACAGCTATTGCTGAACTCCCTAAAGACTATATTC
AATGGCTATTGCGCCAAGACGAGCTGGACGTTTACCTACGTAAAGCATTAGAAAGTGCATTTTAA

Upstream 100 bases:

>100_bases
AAATTCTATTTTTAATATAAATTGTCGTTCTCACCACTTTCCGCCTCACTTCAGGTTTTAAAGTGCGAGGCCAACTGTTA
ACATTCTTGGTTACTCGTAA

Downstream 100 bases:

>100_bases
CGGCCTAAATAGATGATATTCATAAATTCTTCATCATATTGTCATTTTTGAGTTTTATCGTTAGCCCCATTTATATTTTA
TTAAGAACAGTACTGTTTGA

Product: exodeoxyribonuclease X, putative

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MFKGPDMQAIILDTETHTLNGLPIEIAYAPIEINAGKLTLDKSKLFDQLYQVGTPISYAAMAVHHILESDLENQPHYKTF
KLPDTTTYIIGHNIDYDIAAIARCGVDVSHIKPICTLALARKTWPDAEAHNISALIYMISQGSSKARELLKGAHRADADI
ILTANILMHIVYHLNIHDIEELYRVSEEARIPTTINFGKHKGTAIAELPKDYIQWLLRQDELDVYLRKALESAF

Sequences:

>Translated_234_residues
MFKGPDMQAIILDTETHTLNGLPIEIAYAPIEINAGKLTLDKSKLFDQLYQVGTPISYAAMAVHHILESDLENQPHYKTF
KLPDTTTYIIGHNIDYDIAAIARCGVDVSHIKPICTLALARKTWPDAEAHNISALIYMISQGSSKARELLKGAHRADADI
ILTANILMHIVYHLNIHDIEELYRVSEEARIPTTINFGKHKGTAIAELPKDYIQWLLRQDELDVYLRKALESAF
>Mature_234_residues
MFKGPDMQAIILDTETHTLNGLPIEIAYAPIEINAGKLTLDKSKLFDQLYQVGTPISYAAMAVHHILESDLENQPHYKTF
KLPDTTTYIIGHNIDYDIAAIARCGVDVSHIKPICTLALARKTWPDAEAHNISALIYMISQGSSKARELLKGAHRADADI
ILTANILMHIVYHLNIHDIEELYRVSEEARIPTTINFGKHKGTAIAELPKDYIQWLLRQDELDVYLRKALESAF

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=227, Percent_Identity=28.1938325991189, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 26330; Mature: 26330

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGPDMQAIILDTETHTLNGLPIEIAYAPIEINAGKLTLDKSKLFDQLYQVGTPISYAA
CCCCCCCEEEEEECCCCEECCCEEEEEEEEEEECCCEEEECHHHHHHHHHHHCCCHHHHH
MAVHHILESDLENQPHYKTFKLPDTTTYIIGHNIDYDIAAIARCGVDVSHIKPICTLALA
HHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHH
RKTWPDAEAHNISALIYMISQGSSKARELLKGAHRADADIILTANILMHIVYHLNIHDIE
HCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCHHHHH
ELYRVSEEARIPTTINFGKHKGTAIAELPKDYIQWLLRQDELDVYLRKALESAF
HHHHHHHHCCCCEEEECCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFKGPDMQAIILDTETHTLNGLPIEIAYAPIEINAGKLTLDKSKLFDQLYQVGTPISYAA
CCCCCCCEEEEEECCCCEECCCEEEEEEEEEEECCCEEEECHHHHHHHHHHHCCCHHHHH
MAVHHILESDLENQPHYKTFKLPDTTTYIIGHNIDYDIAAIARCGVDVSHIKPICTLALA
HHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHH
RKTWPDAEAHNISALIYMISQGSSKARELLKGAHRADADIILTANILMHIVYHLNIHDIE
HCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCHHHHH
ELYRVSEEARIPTTINFGKHKGTAIAELPKDYIQWLLRQDELDVYLRKALESAF
HHHHHHHHCCCCEEEECCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]