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The map label for this gene is arpC [H]

Identifier: 213158706

GI number: 213158706

Start: 2753274

End: 2754725

Strand: Direct

Name: arpC [H]

Synonym: AB57_2664

Alternate gene names: 213158706

Gene position: 2753274-2754725 (Clockwise)

Preceding gene: 213158705

Following gene: 213158708

Centisome position: 67.97

GC content: 44.49

Gene sequence:

>1452_bases
TTGGTGATTACATCAAAACAAAACTGGTTGTTGTCCTCACTCATGGGAAGCCTGCTCCTTGCAGGCTGCTCATTGGCCCC
AGAATATCAACCTGCAAAAGTTATAGTGCCAGTCAAATTCAAAGAATCTGACCCCAAACTTGAAGATAATAACTGGAAGA
TTGCCCAACCTGCTGATCAGCAAACTCGTGGTGAATGGTGGCGCATTTACAATGATGCTCAACTGAATGAACTTGAACAG
CAAGCTATCGCGGGCAACCAGAACCTAAAAGCGGTGGCAGCAAATATTCAGGCTTCACGTGCATTACGTTCGGCAGCTCA
AGCTGAACGCTTACCAAGTATTGATGCCGGATTTGGGCCAACCCGCCAAAAGCCGTCTCCGGCTTCACTCGGTTTAGATG
ACAATGCACATACTTCGGCTCAAACCTTATGGCGAGCTCAAGCCAATGTTTCATATGAGCTCGATTTATTTGGTCGTGTA
GCAAGTAGTGTCAACGCAGCAACAGCGGATCTACAGCAACAAGAGGCACTATATCAGTCGGCACTTTTAGCTCTACAAGC
GGATGTAGCTCAAGGTTATTTTCTGATACGTCAACTTGATACCGAACAGGCAATTTATAACCGTACAATCAAATTATTAG
GTGAAACACGAGATTTAATGCAGCTTCGTTTTAAAAACGGACTGGTCAGTGAATTAGATGTTTCTCGTGCACAAACCGAA
CTTGCTACCGCACAAACCACTGCCCTAAATATTGCTCGTAACAGAGCCAGTGCAGAACATGCGCTTGCAGTCTTATTAGG
AAAACCACCAGCAGACTTTAACTTGGCAGTTCAACCTTTAACTGCAAATAGTATCCGTCTCCCTGCCGGTTTGCCGTCAA
CTTTACTTGAAAGACGACCCGATATTGCGGCTGCAGAGCGTGCAATGGCAGCAGATAATGCGCGTATTGGAATTGCTCGT
GCAGCATTTTTCCCAAAACTCAGTCTTACAGGAGCTTTAGGTTATGAATCTTCAAGTTTAAGCGAGTTGGGTAAATGGTC
GAGTCGGACTTTTTTACTAGGACCTGTCGCTGGTACTATTTTGTCGTTACCTTTATTTGATGGTGGACAACGTAAAGCAG
GCGTTGCTCAAGCAAGAGCGGCTTATGAGGAAAGCGTCGCCAACTATAGACAAACTGTACTGAATGCATTTCGCGAAGTT
GAAAATGGTTTATCTGATCAAAGAATTCTCGATCAGCAAATTCAGGCTCAAAACCAAGCACTCTCCTCTTCTCGTCATGC
CAATCAACTTTCTCATTTACGTTATCGAGAAGGTGCTATTAGCTATCTTGATGTCATTGATTCTGACCGCACTATTTTGC
AACAAGAACAATTAGCAGCTCAGCTGAAAGGCAGCCAAATCATTGCAAGCATCAATTTAATCCGTGCTTTAGGGGGCGGT
TGGAGTAGTTAA

Upstream 100 bases:

>100_bases
TTACGTTCTGATTCGTACCCTCAACAGCAAACATAAACTGCATTCTGCGGCAGTTCATGAAGCGCCGTTAGCTAGCCCAC
ATGATCATTAAGGAGGACAT

Downstream 100 bases:

>100_bases
TAAAAAAAGCGCCTTACGGCGCTTTTTTTATATACACAAATTATTTTGCATATACAGGGAATTTTGCACAAACAGCTTCA
ACTTTTGCTTTTACATCAGC

Product: multidrug efflux system outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MVITSKQNWLLSSLMGSLLLAGCSLAPEYQPAKVIVPVKFKESDPKLEDNNWKIAQPADQQTRGEWWRIYNDAQLNELEQ
QAIAGNQNLKAVAANIQASRALRSAAQAERLPSIDAGFGPTRQKPSPASLGLDDNAHTSAQTLWRAQANVSYELDLFGRV
ASSVNAATADLQQQEALYQSALLALQADVAQGYFLIRQLDTEQAIYNRTIKLLGETRDLMQLRFKNGLVSELDVSRAQTE
LATAQTTALNIARNRASAEHALAVLLGKPPADFNLAVQPLTANSIRLPAGLPSTLLERRPDIAAAERAMAADNARIGIAR
AAFFPKLSLTGALGYESSSLSELGKWSSRTFLLGPVAGTILSLPLFDGGQRKAGVAQARAAYEESVANYRQTVLNAFREV
ENGLSDQRILDQQIQAQNQALSSSRHANQLSHLRYREGAISYLDVIDSDRTILQQEQLAAQLKGSQIIASINLIRALGGG
WSS

Sequences:

>Translated_483_residues
MVITSKQNWLLSSLMGSLLLAGCSLAPEYQPAKVIVPVKFKESDPKLEDNNWKIAQPADQQTRGEWWRIYNDAQLNELEQ
QAIAGNQNLKAVAANIQASRALRSAAQAERLPSIDAGFGPTRQKPSPASLGLDDNAHTSAQTLWRAQANVSYELDLFGRV
ASSVNAATADLQQQEALYQSALLALQADVAQGYFLIRQLDTEQAIYNRTIKLLGETRDLMQLRFKNGLVSELDVSRAQTE
LATAQTTALNIARNRASAEHALAVLLGKPPADFNLAVQPLTANSIRLPAGLPSTLLERRPDIAAAERAMAADNARIGIAR
AAFFPKLSLTGALGYESSSLSELGKWSSRTFLLGPVAGTILSLPLFDGGQRKAGVAQARAAYEESVANYRQTVLNAFREV
ENGLSDQRILDQQIQAQNQALSSSRHANQLSHLRYREGAISYLDVIDSDRTILQQEQLAAQLKGSQIIASINLIRALGGG
WSS
>Mature_483_residues
MVITSKQNWLLSSLMGSLLLAGCSLAPEYQPAKVIVPVKFKESDPKLEDNNWKIAQPADQQTRGEWWRIYNDAQLNELEQ
QAIAGNQNLKAVAANIQASRALRSAAQAERLPSIDAGFGPTRQKPSPASLGLDDNAHTSAQTLWRAQANVSYELDLFGRV
ASSVNAATADLQQQEALYQSALLALQADVAQGYFLIRQLDTEQAIYNRTIKLLGETRDLMQLRFKNGLVSELDVSRAQTE
LATAQTTALNIARNRASAEHALAVLLGKPPADFNLAVQPLTANSIRLPAGLPSTLLERRPDIAAAERAMAADNARIGIAR
AAFFPKLSLTGALGYESSSLSELGKWSSRTFLLGPVAGTILSLPLFDGGQRKAGVAQARAAYEESVANYRQTVLNAFREV
ENGLSDQRILDQQIQAQNQALSSSRHANQLSHLRYREGAISYLDVIDSDRTILQQEQLAAQLKGSQIIASINLIRALGGG
WSS

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=471, Percent_Identity=31.2101910828025, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI2367348, Length=496, Percent_Identity=27.6209677419355, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52466; Mature: 52466

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVITSKQNWLLSSLMGSLLLAGCSLAPEYQPAKVIVPVKFKESDPKLEDNNWKIAQPADQ
CEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCC
QTRGEWWRIYNDAQLNELEQQAIAGNQNLKAVAANIQASRALRSAAQAERLPSIDAGFGP
CCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TRQKPSPASLGLDDNAHTSAQTLWRAQANVSYELDLFGRVASSVNAATADLQQQEALYQS
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLALQADVAQGYFLIRQLDTEQAIYNRTIKLLGETRDLMQLRFKNGLVSELDVSRAQTE
HHHHHHHHHHHHEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LATAQTTALNIARNRASAEHALAVLLGKPPADFNLAVQPLTANSIRLPAGLPSTLLERRP
HHHHHHHHHHHHHHHCHHHHEEEEEECCCCCCCCEEEEEECCCCEECCCCCCHHHHHCCC
DIAAAERAMAADNARIGIARAAFFPKLSLTGALGYESSSLSELGKWSSRTFLLGPVAGTI
CHHHHHHHHHCCCCCEEEHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECHHHHH
LSLPLFDGGQRKAGVAQARAAYEESVANYRQTVLNAFREVENGLSDQRILDQQIQAQNQA
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LSSSRHANQLSHLRYREGAISYLDVIDSDRTILQQEQLAAQLKGSQIIASINLIRALGGG
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
WSS
CCC
>Mature Secondary Structure
MVITSKQNWLLSSLMGSLLLAGCSLAPEYQPAKVIVPVKFKESDPKLEDNNWKIAQPADQ
CEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCC
QTRGEWWRIYNDAQLNELEQQAIAGNQNLKAVAANIQASRALRSAAQAERLPSIDAGFGP
CCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TRQKPSPASLGLDDNAHTSAQTLWRAQANVSYELDLFGRVASSVNAATADLQQQEALYQS
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLALQADVAQGYFLIRQLDTEQAIYNRTIKLLGETRDLMQLRFKNGLVSELDVSRAQTE
HHHHHHHHHHHHEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LATAQTTALNIARNRASAEHALAVLLGKPPADFNLAVQPLTANSIRLPAGLPSTLLERRP
HHHHHHHHHHHHHHHCHHHHEEEEEECCCCCCCCEEEEEECCCCEECCCCCCHHHHHCCC
DIAAAERAMAADNARIGIARAAFFPKLSLTGALGYESSSLSELGKWSSRTFLLGPVAGTI
CHHHHHHHHHCCCCCEEEHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECHHHHH
LSLPLFDGGQRKAGVAQARAAYEESVANYRQTVLNAFREVENGLSDQRILDQQIQAQNQA
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LSSSRHANQLSHLRYREGAISYLDVIDSDRTILQQEQLAAQLKGSQIIASINLIRALGGG
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
WSS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]