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The map label for this gene is gpsA

Identifier: 213158660

GI number: 213158660

Start: 2705299

End: 2706372

Strand: Reverse

Name: gpsA

Synonym: AB57_2614

Alternate gene names: 213158660

Gene position: 2706372-2705299 (Counterclockwise)

Preceding gene: 213158661

Following gene: 213158659

Centisome position: 66.82

GC content: 39.94

Gene sequence:

>1074_bases
ATGGCTGAATTTAAGTTTACAGATTTGGTGGAACCTGTTGCGGTCGATAAAAAAACGGCATTACGTATTACCGTTTTAGG
GGGCGGTAGCTTTGGTACAGCTATGGCAAATTTAGCTGCTCGTAATGGCTGCGATACCATGATCTGGATTCGTGATGCCG
AAACAGCAGAAGAAATTAATAAAACCCATATTAATAAACGTTATTTACCAGACTTCACTTTAGAATCTTCATTACGTGCA
GTTTCTGATCTTGAGCAAGCGGTATGTGATCGAGATATTATTTTAGTTGCAATTCCAAGCCACTCATTCCGTGATGTTTT
AAAACAAATAGCGCCTTATATTACTGCACAAGCTGTGGTGTCTTTAACCAAAGGTGTTGAAGCTAAAACATTTAGCTTCA
TGAGTGATATTATTCGTGAAGAATTACCAGAAGTGCCGTATGGCGTATTGTCAGGACCAAATCTCGCTAAAGAAATTATG
GCAGGTATGCCTTCTGGTACTGTAATTGCAAGTGATTCTGAACTCGTCCGTTATGCCGTACAACATGCACTTCATAGTGC
GTTATTCCGCGTTTTTGGTAGCGATGATGTGCATGGAGTTGAGTTAGGCGGTGCGCTTAAGAATATTTATGCCGTTGCTA
TGGGAATTGGAGCAGCATATAAAATTGGTGAAAATACCAAGAGTATGATTTTAACGCGTGCTTTGGCTGAAATGAGCCGT
TTCGCGGTAAAACAAGGTGCAAACCCACTTACGTTCTTAGGTTTATCTGGAGTAGGTGATTTATTTGCGACTTGTAATAG
TCCATTAAGCCGTAATTATCAAATTGGTTATGCGCTAGGTTCTGGTAAAACGCTTGAACAAGCGAGTAAAGAATTAGGTC
AAACTGCAGAAGGTATTAACACGATTGTTCAGGTGCGTGGCAAGGCACAAGAACTAGACGTATATATGCCAATTACCAAT
GCTTTATATGAGGTCATTTTTGAAGGCGCTCCACCATTAAATATTGCACTTTCTCTTATGAAAAATGGACACCGTAGTGA
TGTTGAGTTTGTTTTACCTCATCATGAAGTCTGA

Upstream 100 bases:

>100_bases
GCTAAAGCAATTGCACCGCGTGCAGATATTGATAGTAAAGAATTCGTAAAAGTTTGGCAGGCTTAAACGTCTGTAAAAGT
AAGAAATAGGATAATAAAGC

Downstream 100 bases:

>100_bases
CGAATAAATGTCATAAATTGTGGTTATAATGCAGGAATTGTTTACAAGGAAATTTTATGCAACTGACATTAGTTCGTCAT
GGGGAAGCTGCTCCGCCAGT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MAEFKFTDLVEPVAVDKKTALRITVLGGGSFGTAMANLAARNGCDTMIWIRDAETAEEINKTHINKRYLPDFTLESSLRA
VSDLEQAVCDRDIILVAIPSHSFRDVLKQIAPYITAQAVVSLTKGVEAKTFSFMSDIIREELPEVPYGVLSGPNLAKEIM
AGMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAVAMGIGAAYKIGENTKSMILTRALAEMSR
FAVKQGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLEQASKELGQTAEGINTIVQVRGKAQELDVYMPITN
ALYEVIFEGAPPLNIALSLMKNGHRSDVEFVLPHHEV

Sequences:

>Translated_357_residues
MAEFKFTDLVEPVAVDKKTALRITVLGGGSFGTAMANLAARNGCDTMIWIRDAETAEEINKTHINKRYLPDFTLESSLRA
VSDLEQAVCDRDIILVAIPSHSFRDVLKQIAPYITAQAVVSLTKGVEAKTFSFMSDIIREELPEVPYGVLSGPNLAKEIM
AGMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAVAMGIGAAYKIGENTKSMILTRALAEMSR
FAVKQGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLEQASKELGQTAEGINTIVQVRGKAQELDVYMPITN
ALYEVIFEGAPPLNIALSLMKNGHRSDVEFVLPHHEV
>Mature_356_residues
AEFKFTDLVEPVAVDKKTALRITVLGGGSFGTAMANLAARNGCDTMIWIRDAETAEEINKTHINKRYLPDFTLESSLRAV
SDLEQAVCDRDIILVAIPSHSFRDVLKQIAPYITAQAVVSLTKGVEAKTFSFMSDIIREELPEVPYGVLSGPNLAKEIMA
GMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAVAMGIGAAYKIGENTKSMILTRALAEMSRF
AVKQGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLEQASKELGQTAEGINTIVQVRGKAQELDVYMPITNA
LYEVIFEGAPPLNIALSLMKNGHRSDVEFVLPHHEV

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=334, Percent_Identity=30.8383233532934, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI33695088, Length=337, Percent_Identity=30.2670623145401, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=38.719512195122, Blast_Score=238, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI32564399, Length=333, Percent_Identity=27.9279279279279, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193210136, Length=341, Percent_Identity=27.8592375366569, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32564403, Length=341, Percent_Identity=27.8592375366569, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17507425, Length=335, Percent_Identity=28.3582089552239, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI193210134, Length=330, Percent_Identity=25.1515151515152, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324513, Length=347, Percent_Identity=30.2593659942363, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320181, Length=353, Percent_Identity=29.7450424929178, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI22026922, Length=359, Percent_Identity=29.8050139275766, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136204, Length=349, Percent_Identity=30.6590257879656, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17136202, Length=339, Percent_Identity=30.9734513274336, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17136200, Length=349, Percent_Identity=30.6590257879656, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45551945, Length=290, Percent_Identity=25.8620689655172, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281362270, Length=290, Percent_Identity=25.8620689655172, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648969, Length=250, Percent_Identity=26.8, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_ACIB3 (B7GZW3)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002325090.1
- ProteinModelPortal:   B7GZW3
- SMR:   B7GZW3
- GeneID:   7057610
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_001183
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 38537; Mature: 38406

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 207-207 BINDING 124-124 BINDING 124-124 BINDING 156-156 BINDING 271-271 BINDING 297-297

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFKFTDLVEPVAVDKKTALRITVLGGGSFGTAMANLAARNGCDTMIWIRDAETAEEIN
CCCCCCHHHHCHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHH
KTHINKRYLPDFTLESSLRAVSDLEQAVCDRDIILVAIPSHSFRDVLKQIAPYITAQAVV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
SLTKGVEAKTFSFMSDIIREELPEVPYGVLSGPNLAKEIMAGMPSGTVIASDSELVRYAV
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHH
QHALHSALFRVFGSDDVHGVELGGALKNIYAVAMGIGAAYKIGENTKSMILTRALAEMSR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHH
FAVKQGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLEQASKELGQTAEGIN
HHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
TIVQVRGKAQELDVYMPITNALYEVIFEGAPPLNIALSLMKNGHRSDVEFVLPHHEV
HHHHHCCCHHHEEEEECHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCC
>Mature Secondary Structure 
AEFKFTDLVEPVAVDKKTALRITVLGGGSFGTAMANLAARNGCDTMIWIRDAETAEEIN
CCCCCHHHHCHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHH
KTHINKRYLPDFTLESSLRAVSDLEQAVCDRDIILVAIPSHSFRDVLKQIAPYITAQAVV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
SLTKGVEAKTFSFMSDIIREELPEVPYGVLSGPNLAKEIMAGMPSGTVIASDSELVRYAV
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHH
QHALHSALFRVFGSDDVHGVELGGALKNIYAVAMGIGAAYKIGENTKSMILTRALAEMSR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHH
FAVKQGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLEQASKELGQTAEGIN
HHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
TIVQVRGKAQELDVYMPITNALYEVIFEGAPPLNIALSLMKNGHRSDVEFVLPHHEV
HHHHHCCCHHHEEEEECHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA