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The map label for this gene is gltS [H]

Identifier: 213158626

GI number: 213158626

Start: 2671691

End: 2672926

Strand: Reverse

Name: gltS [H]

Synonym: AB57_2580

Alternate gene names: 213158626

Gene position: 2672926-2671691 (Counterclockwise)

Preceding gene: 213158631

Following gene: 213158623

Centisome position: 65.99

GC content: 40.61

Gene sequence:

>1236_bases
ATGGAATTTGTTTTTAATGGTTTTTATACACTAATTTCGGCGGTCATCGTTCTATTGTTGGGTCGCTTTCTTGTCAATCG
GATTGATTTTTTAAAACGTTATAATATCCCTGAACCAGTAGCAGGTGGTTTGGTCGCTGCGGTAGTTTCTTTACTTGTCC
ACACTTTCTGGGGATACAGTATTGTTTTTAGCAGTGAATTACAAACCAGCTTTATGCTCGTGTTCTTTGCTTCAATTGGT
TTAAGTGCCAATTTTATGAAGCTTAAAGAGGGTGGTACTGCTTTAGTCATCTTCTTAATTTGTGTAGCCTCATTTATTGT
TGTTCAAAATGCTGTCGGTATGAGCCTTGCAACCTTATTGGGTCTAGACCCACTTATTGGTTTGATTGCAGGTTCAATTA
CTTTAACCGGTGGTCATGGTACAGCAGGTGCTTGGGGTGAAATTTTAGAAAGCCAGCATGGTATTCAGGGTGCTTTAGCG
TTAGGTATGGCAAGTGCTACGTTTGGCTTGATTATTGGTGGTGTCATTGGTGGTCCTTTAGCCAAATTGCTTATTAATCG
TTATAGCCTTGCTCAAGCAAAAACCAATGCTGAAATTCAGCAGCGTGACACGCATGTTGAACAAAATTCAGATGATCTTG
CACCGTTTGAAAACCCGCATCAAGTTCGTTTAATTACTGCCGACAATGCAATTACCACGCTTGGTATGTTTGCAGCATGT
TTAGCATTTGCTGAATTTATGACTGGTTTCAGTAAGGGAACTTGGTTTGAGTTACCAACTTTCGTTTGGGCGCTTGGTGG
CGGTGTAATCTTAAGAAATATTTTAGAAAGCGTGTTGAAGGTTGATATCTTTGACCGCGCGATTGACGTTTTTGGTAATG
CGTCTTTATCTCTTTATTTAGCAATGGCATTGCTTTCATTAAAGCTTTGGCAACTTGCTGACTTAGCAGGTCCACTTGTG
GTTATTTTAGGTGCTCAAACACTGACTATGGCTTTATATGCAGCATTTGTGACTTTCCGTGTAATGGGGAAAAATTACGA
TGCGGCAGTATTGGCAGCAGGTCACTGTGGTTTCGGTATGGGGGCTACACCAACCGCCGTTGCAAATATGCAGGCGATTA
CCAATATGTATGGCCCATCGCATAAAGCATTCTTAATTGTTCCGCTTTGTGGTGCATTCTTTGTCGACTTGATTAATGCA
ACTGTGATTCAGCTTATGTTGAAATTTATTGCTTAA

Upstream 100 bases:

>100_bases
GGGTAATTTTGTAAAGTTTATTTGTGTTTTTTTTACATATTAAAAAATAAAATATAATTATTTTACAATCCGTTAGGAAT
GTAATCAGAAAGTAGTATAT

Downstream 100 bases:

>100_bases
TTAAAAAAAGCCCGTAAGGGCTTTTTTTATGGGTGTCTTTTTATGAATATTAATATATAGCAACAGGATTAATATTCACT
TGTGTAGAACCGACATATAG

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MEFVFNGFYTLISAVIVLLLGRFLVNRIDFLKRYNIPEPVAGGLVAAVVSLLVHTFWGYSIVFSSELQTSFMLVFFASIG
LSANFMKLKEGGTALVIFLICVASFIVVQNAVGMSLATLLGLDPLIGLIAGSITLTGGHGTAGAWGEILESQHGIQGALA
LGMASATFGLIIGGVIGGPLAKLLINRYSLAQAKTNAEIQQRDTHVEQNSDDLAPFENPHQVRLITADNAITTLGMFAAC
LAFAEFMTGFSKGTWFELPTFVWALGGGVILRNILESVLKVDIFDRAIDVFGNASLSLYLAMALLSLKLWQLADLAGPLV
VILGAQTLTMALYAAFVTFRVMGKNYDAAVLAAGHCGFGMGATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINA
TVIQLMLKFIA

Sequences:

>Translated_411_residues
MEFVFNGFYTLISAVIVLLLGRFLVNRIDFLKRYNIPEPVAGGLVAAVVSLLVHTFWGYSIVFSSELQTSFMLVFFASIG
LSANFMKLKEGGTALVIFLICVASFIVVQNAVGMSLATLLGLDPLIGLIAGSITLTGGHGTAGAWGEILESQHGIQGALA
LGMASATFGLIIGGVIGGPLAKLLINRYSLAQAKTNAEIQQRDTHVEQNSDDLAPFENPHQVRLITADNAITTLGMFAAC
LAFAEFMTGFSKGTWFELPTFVWALGGGVILRNILESVLKVDIFDRAIDVFGNASLSLYLAMALLSLKLWQLADLAGPLV
VILGAQTLTMALYAAFVTFRVMGKNYDAAVLAAGHCGFGMGATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINA
TVIQLMLKFIA
>Mature_411_residues
MEFVFNGFYTLISAVIVLLLGRFLVNRIDFLKRYNIPEPVAGGLVAAVVSLLVHTFWGYSIVFSSELQTSFMLVFFASIG
LSANFMKLKEGGTALVIFLICVASFIVVQNAVGMSLATLLGLDPLIGLIAGSITLTGGHGTAGAWGEILESQHGIQGALA
LGMASATFGLIIGGVIGGPLAKLLINRYSLAQAKTNAEIQQRDTHVEQNSDDLAPFENPHQVRLITADNAITTLGMFAAC
LAFAEFMTGFSKGTWFELPTFVWALGGGVILRNILESVLKVDIFDRAIDVFGNASLSLYLAMALLSLKLWQLADLAGPLV
VILGAQTLTMALYAAFVTFRVMGKNYDAAVLAAGHCGFGMGATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINA
TVIQLMLKFIA

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=387, Percent_Identity=51.6795865633075, Blast_Score=348, Evalue=3e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43747; Mature: 43747

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFVFNGFYTLISAVIVLLLGRFLVNRIDFLKRYNIPEPVAGGLVAAVVSLLVHTFWGYS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHH
IVFSSELQTSFMLVFFASIGLSANFMKLKEGGTALVIFLICVASFIVVQNAVGMSLATLL
EEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDPLIGLIAGSITLTGGHGTAGAWGEILESQHGIQGALALGMASATFGLIIGGVIGGPL
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLLINRYSLAQAKTNAEIQQRDTHVEQNSDDLAPFENPHQVRLITADNAITTLGMFAAC
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
LAFAEFMTGFSKGTWFELPTFVWALGGGVILRNILESVLKVDIFDRAIDVFGNASLSLYL
HHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMALLSLKLWQLADLAGPLVVILGAQTLTMALYAAFVTFRVMGKNYDAAVLAAGHCGFGM
HHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINATVIQLMLKFIA
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEFVFNGFYTLISAVIVLLLGRFLVNRIDFLKRYNIPEPVAGGLVAAVVSLLVHTFWGYS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHH
IVFSSELQTSFMLVFFASIGLSANFMKLKEGGTALVIFLICVASFIVVQNAVGMSLATLL
EEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDPLIGLIAGSITLTGGHGTAGAWGEILESQHGIQGALALGMASATFGLIIGGVIGGPL
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLLINRYSLAQAKTNAEIQQRDTHVEQNSDDLAPFENPHQVRLITADNAITTLGMFAAC
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
LAFAEFMTGFSKGTWFELPTFVWALGGGVILRNILESVLKVDIFDRAIDVFGNASLSLYL
HHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMALLSLKLWQLADLAGPLVVILGAQTLTMALYAAFVTFRVMGKNYDAAVLAAGHCGFGM
HHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINATVIQLMLKFIA
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]