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The map label for this gene is prmA

Identifier: 213158568

GI number: 213158568

Start: 2616036

End: 2616941

Strand: Direct

Name: prmA

Synonym: AB57_2522

Alternate gene names: 213158568

Gene position: 2616036-2616941 (Clockwise)

Preceding gene: 213158567

Following gene: 213158569

Centisome position: 64.59

GC content: 39.07

Gene sequence:

>906_bases
GTGAAGTGGTTACAAATACACATTACCGTTGATCAAGAACAAGTTGAATTCACAGAAACACTTTTAATGTCTCTAGGTGC
GGTAAGCGTAACTTTGGATGATGCCGAAGATCAGGCTTTACTGGAACCATTACCAGGTGAAACACCACTCTGGAATAAAG
TCATTGTTACTGGTATTTACCAACAAGACGAACAAGACCCAATTGATGTTGATACTTTAGAAGCTTTCTTAAAAGCACAA
CTTCCAGATGTGCCGATGCGTCATGAAGAACTTGAAGATCAAGTTTGGGAACGCGCATGGATGGATTATTATGAACCAAT
TCAGATTGGGGAAAAATTCTGGATTGTTCCTGAATGGTTAGAGCCACCAGAAGCAGATGCTACAAATATTAAGCTTGATC
CAGGCCTTGCTTTTGGTACAGGTAATCATGCAAGTACTTTCTTATGCTTACAATGGTTAGGTAAAACTGATGTTAAAGAT
AAGATCGTGATTGATTATGGCTGTGGCTCAGGCATTTTAGGTGTTGCAGCTTTATTATTAGGCGCTAAGAAAGTCTATGC
GACAGACATCGACCCACAAGCAGTTTTAGCAACTAAACAAAATGCAGAACTCAATGGTGTATTAGACCGTTTATATGTAG
GTCTTCCTGAAGAGTTTGATCAAGAATTCAAACCTCAACAAGCAGATGTTTTAGTCGCAAATATTTTAGCGGGTCCTTTA
ATGGCACTTGCGCCAGAGTTTGCAAAATTACTTAAATCTGATGGTGACTTCGCACTTGCTGGTGTAATCGAAGAGCAAGT
TGCTGATGTTTCAGGTGTTTATTCTGAATTTTTTGATATATTAGATGTCGAAAAGCGCGAAGAAAACTGGTGCCGCATTT
CAGGAAAACGTAAAACAACAAATTGA

Upstream 100 bases:

>100_bases
TCATTTTCAAAAAGCGGTCCATTAAAGATGGGCCGTTTTCTTTTTTAAACTACTCTAGTCGGCTACAATATGCCTTTAAA
TAAAATTTTAGGTCCTTTTC

Downstream 100 bases:

>100_bases
GATGTTTTAACTCATGAATGAAAAACAAACCCGCTGCCCTAAGTGTCTAACAGTTTATAAAGTTTCTCTTACTCAGTTAA
CTGTTGCTCAGGGTATGGTT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKWLQIHITVDQEQVEFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQQDEQDPIDVDTLEAFLKAQ
LPDVPMRHEELEDQVWERAWMDYYEPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDVKD
KIVIDYGCGSGILGVAALLLGAKKVYATDIDPQAVLATKQNAELNGVLDRLYVGLPEEFDQEFKPQQADVLVANILAGPL
MALAPEFAKLLKSDGDFALAGVIEEQVADVSGVYSEFFDILDVEKREENWCRISGKRKTTN

Sequences:

>Translated_301_residues
MKWLQIHITVDQEQVEFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQQDEQDPIDVDTLEAFLKAQ
LPDVPMRHEELEDQVWERAWMDYYEPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDVKD
KIVIDYGCGSGILGVAALLLGAKKVYATDIDPQAVLATKQNAELNGVLDRLYVGLPEEFDQEFKPQQADVLVANILAGPL
MALAPEFAKLLKSDGDFALAGVIEEQVADVSGVYSEFFDILDVEKREENWCRISGKRKTTN
>Mature_301_residues
MKWLQIHITVDQEQVEFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQQDEQDPIDVDTLEAFLKAQ
LPDVPMRHEELEDQVWERAWMDYYEPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDVKD
KIVIDYGCGSGILGVAALLLGAKKVYATDIDPQAVLATKQNAELNGVLDRLYVGLPEEFDQEFKPQQADVLVANILAGPL
MALAPEFAKLLKSDGDFALAGVIEEQVADVSGVYSEFFDILDVEKREENWCRISGKRKTTN

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=300, Percent_Identity=45.6666666666667, Blast_Score=231, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_ACIB3 (B7H0I7)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002325183.1
- ProteinModelPortal:   B7H0I7
- GeneID:   7058612
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_001280
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33593; Mature: 33593

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWLQIHITVDQEQVEFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIY
CCEEEEEEEECHHHHHHHHHHHHHHCCEEEEECCCCCHHHHCCCCCCCCCCCHHEEEEEC
QQDEQDPIDVDTLEAFLKAQLPDVPMRHEELEDQVWERAWMDYYEPIQIGEKFWIVPEWL
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCEEEEECCCC
EPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDVKDKIVIDYGCGSGILGVAALLL
CCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHH
GAKKVYATDIDPQAVLATKQNAELNGVLDRLYVGLPEEFDQEFKPQQADVLVANILAGPL
CCHHHEEECCCCHHEEEECCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHH
MALAPEFAKLLKSDGDFALAGVIEEQVADVSGVYSEFFDILDVEKREENWCRISGKRKTT
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
N
C
>Mature Secondary Structure
MKWLQIHITVDQEQVEFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIY
CCEEEEEEEECHHHHHHHHHHHHHHCCEEEEECCCCCHHHHCCCCCCCCCCCHHEEEEEC
QQDEQDPIDVDTLEAFLKAQLPDVPMRHEELEDQVWERAWMDYYEPIQIGEKFWIVPEWL
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCEEEEECCCC
EPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDVKDKIVIDYGCGSGILGVAALLL
CCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHH
GAKKVYATDIDPQAVLATKQNAELNGVLDRLYVGLPEEFDQEFKPQQADVLVANILAGPL
CCHHHEEECCCCHHEEEECCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHH
MALAPEFAKLLKSDGDFALAGVIEEQVADVSGVYSEFFDILDVEKREENWCRISGKRKTT
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA