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The map label for this gene is folB [H]

Identifier: 213158525

GI number: 213158525

Start: 2570819

End: 2571199

Strand: Reverse

Name: folB [H]

Synonym: AB57_2476

Alternate gene names: 213158525

Gene position: 2571199-2570819 (Counterclockwise)

Preceding gene: 213158526

Following gene: 213158524

Centisome position: 63.48

GC content: 42.26

Gene sequence:

>381_bases
ATGGATGCCATTATTATTGAAGGCTTGAAGGTTGAGACAGTGATTGGCTGTTTCAACTGGGAAAGACAAATCATTCAACC
TTTAATGTTGGATTTAACCATCCATAATGATTTGAGCCGAGCTGCAGCGTCTGACAAGCTTGAGGACACACTCAACTATG
CCCAGATTTGTGAGTTATCGGCTCAAACCATTCAGAAAGCCAAGCCTGAATTAATTGAGCATGCAGCACATCTCGTTCTG
CAATGTCTGTTTGAAACCTTTCCAACAATTGAAAAAATTACCATAACCATCCGTAAGCCAGCCATCATTGCAGAAGCAAA
TGCTGTAGGAATTCGTCTTGAACGCACCAGAAACAATTTTTGCGCTCGCCCTAGCGAGTAA

Upstream 100 bases:

>100_bases
ACTCGCACCTTATACTGATATTTATGCAGACCAACGTTTGAAAATGGTTCAAAATATGGAACCTGCTTCGTTGTTAAAGC
ACTAAGGTCAGTTTAAATTT

Downstream 100 bases:

>100_bases
TTTAGACGCAGATCAGCACTTTACTTTTGCCTATACGCAATTAGCAACTTTGGGGAAAGTGCAGTTTTCATCTGTTTATC
AAATTCCATGCCGAGATGGT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MDAIIIEGLKVETVIGCFNWERQIIQPLMLDLTIHNDLSRAAASDKLEDTLNYAQICELSAQTIQKAKPELIEHAAHLVL
QCLFETFPTIEKITITIRKPAIIAEANAVGIRLERTRNNFCARPSE

Sequences:

>Translated_126_residues
MDAIIIEGLKVETVIGCFNWERQIIQPLMLDLTIHNDLSRAAASDKLEDTLNYAQICELSAQTIQKAKPELIEHAAHLVL
QCLFETFPTIEKITITIRKPAIIAEANAVGIRLERTRNNFCARPSE
>Mature_126_residues
MDAIIIEGLKVETVIGCFNWERQIIQPLMLDLTIHNDLSRAAASDKLEDTLNYAQICELSAQTIQKAKPELIEHAAHLVL
QCLFETFPTIEKITITIRKPAIIAEANAVGIRLERTRNNFCARPSE

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=118, Percent_Identity=36.4406779661017, Blast_Score=76, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14185; Mature: 14185

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIIIEGLKVETVIGCFNWERQIIQPLMLDLTIHNDLSRAAASDKLEDTLNYAQICELS
CCCEEECCCEEEHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AQTIQKAKPELIEHAAHLVLQCLFETFPTIEKITITIRKPAIIAEANAVGIRLERTRNNF
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCEEEEEEECCCCCC
CARPSE
CCCCCC
>Mature Secondary Structure
MDAIIIEGLKVETVIGCFNWERQIIQPLMLDLTIHNDLSRAAASDKLEDTLNYAQICELS
CCCEEECCCEEEHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AQTIQKAKPELIEHAAHLVLQCLFETFPTIEKITITIRKPAIIAEANAVGIRLERTRNNF
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCEEEEEEECCCCCC
CARPSE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]