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The map label for this gene is eat [C]

Identifier: 213158485

GI number: 213158485

Start: 2523413

End: 2524849

Strand: Direct

Name: eat [C]

Synonym: AB57_2435

Alternate gene names: 213158485

Gene position: 2523413-2524849 (Clockwise)

Preceding gene: 213158484

Following gene: 213158486

Centisome position: 62.3

GC content: 42.94

Gene sequence:

>1437_bases
ATGAATCAACCAGAAACAGCTTCCGTTATTTCTTCAAGCGCAGAAGTCTCATCAGCAGAATATTTTGCTCAGCGCCAACT
TAAACAAGGTACCGTGGGTTGGTTACTCCTGATTGGTTTAGGCGTAGCGTATGTGATATCAGGTGATTTTGCCGGCTGGA
ACTTTGGTATTGCTCAAGGTGGTTGGGGTGGTATGTTTATTGCCACTGCTCTTGCTGCCTTGATGTACCTGTGCCTATGT
CTTTCTATGTCAGAAATGTCCACCATGATGCCGACAGCAGGTGGCGGTTATAGTTTTGCCCGTGCTGCCTTTGGGCCTTT
TGGTGGTTATTTAACAGGCACAGCGATTTTAATTGAATATGCAATTGCGCCTGCCGCTATTGCCGTATTTATTGGTGGTT
ATTGCGAATCTCTATTTGGTATTAATGGCTGGATGATTTACCTCGCCTGTTACGCCATTTTTATGGGTATACATCTCAAA
GGCGCCGGCGAAGCTTTAAAAATCATGTTTGCGATTACACTTGTCGCCGCTGTTGCCCTTGTCGTGTTTATTGGGGCAAT
GATTCCACACTTTAATGCACAAAATTTATTTGATATTCCAGTTAGTACAGGTGTTGGCGCAAGTCTTTTTTTACCTCATG
GCTACTTGGGCATCTGGGCCGCGGTTCCTTTTGCTATCTGGTTTTTTCTTGCAGTAGAAGGTGTTCCGTTAGCAGCAGAA
GAAGCAAAAGATCCAGCCAAATCTCTGCCACGCGGTTTAATCGGTGCAATGCTCATCTTAACAGCATTTGGCATGCTTAT
TTTGTTCTTGGGTGCAGGCGCAGCAGGTGCAAGTACTTTACAAAACTCAGGTGCCCCTCTGGTAGATGCTTTGGTTAAAG
TTTATGGCACCAACACTTGGCTTGCGACATTCGTAAACTTTGTGGGTTTAGCTGGTTTAATCGCAAGTTTCTTCTCAATT
ATCTATGCCTATTCGCGTCAAATCTTTGCATTGTCACGAGCTGGTTACTTACCTACTTCACTCTCTTTAACCAATAAAAA
TAAAGCCCCTTATCTTGCAATTATTATTCCGGGCATTATCGGGTTCTTGCTTTCACTTACCAAAGAAGGCGATTCACTCA
TTTTAATCGCGGTTTTTGGTGCAACTATTTCTTATGTGCTGATTCTTTTATCACACATCAAACTGCGCTTATCTAAACCC
GACATGCCTCGTCCTTATAAAACTCCAGGAGGAATCATCACTTCAAGCATTGCACTAGTTTTAGCAGTCGCTGCTGTGGT
CGCAGGTTTTGTTGTTAATCCGAAAGTGTGGTTTATTGCTGCCGGTATCTATGTCGTATTTATTGCTTACTTCTTGTTCT
ACAGTCGCTATCATTTAGTGAAAGGAACACCAGAAGAAGAGTTTGCAAATATTAAAGCCGCAGAACAAGAACTATAA

Upstream 100 bases:

>100_bases
TTACTATCTGGAATAAAAAAGCATCATCTAATATTTAAAGCACATCATTTAGGCATTGCTTTTGCATTCATTCATACAAA
CCAACTCGCAGGAGTATTGT

Downstream 100 bases:

>100_bases
ATAAAAGGATGTAACTATGAGTTATCGCAATATTGTCGCCAATCAACAGTATCACTTTGCTGACCTAAAAACGTTAATGG
CCAAAGCTACACCGTTACGT

Product: ethanolamine permease

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MNQPETASVISSSAEVSSAEYFAQRQLKQGTVGWLLLIGLGVAYVISGDFAGWNFGIAQGGWGGMFIATALAALMYLCLC
LSMSEMSTMMPTAGGGYSFARAAFGPFGGYLTGTAILIEYAIAPAAIAVFIGGYCESLFGINGWMIYLACYAIFMGIHLK
GAGEALKIMFAITLVAAVALVVFIGAMIPHFNAQNLFDIPVSTGVGASLFLPHGYLGIWAAVPFAIWFFLAVEGVPLAAE
EAKDPAKSLPRGLIGAMLILTAFGMLILFLGAGAAGASTLQNSGAPLVDALVKVYGTNTWLATFVNFVGLAGLIASFFSI
IYAYSRQIFALSRAGYLPTSLSLTNKNKAPYLAIIIPGIIGFLLSLTKEGDSLILIAVFGATISYVLILLSHIKLRLSKP
DMPRPYKTPGGIITSSIALVLAVAAVVAGFVVNPKVWFIAAGIYVVFIAYFLFYSRYHLVKGTPEEEFANIKAAEQEL

Sequences:

>Translated_478_residues
MNQPETASVISSSAEVSSAEYFAQRQLKQGTVGWLLLIGLGVAYVISGDFAGWNFGIAQGGWGGMFIATALAALMYLCLC
LSMSEMSTMMPTAGGGYSFARAAFGPFGGYLTGTAILIEYAIAPAAIAVFIGGYCESLFGINGWMIYLACYAIFMGIHLK
GAGEALKIMFAITLVAAVALVVFIGAMIPHFNAQNLFDIPVSTGVGASLFLPHGYLGIWAAVPFAIWFFLAVEGVPLAAE
EAKDPAKSLPRGLIGAMLILTAFGMLILFLGAGAAGASTLQNSGAPLVDALVKVYGTNTWLATFVNFVGLAGLIASFFSI
IYAYSRQIFALSRAGYLPTSLSLTNKNKAPYLAIIIPGIIGFLLSLTKEGDSLILIAVFGATISYVLILLSHIKLRLSKP
DMPRPYKTPGGIITSSIALVLAVAAVVAGFVVNPKVWFIAAGIYVVFIAYFLFYSRYHLVKGTPEEEFANIKAAEQEL
>Mature_478_residues
MNQPETASVISSSAEVSSAEYFAQRQLKQGTVGWLLLIGLGVAYVISGDFAGWNFGIAQGGWGGMFIATALAALMYLCLC
LSMSEMSTMMPTAGGGYSFARAAFGPFGGYLTGTAILIEYAIAPAAIAVFIGGYCESLFGINGWMIYLACYAIFMGIHLK
GAGEALKIMFAITLVAAVALVVFIGAMIPHFNAQNLFDIPVSTGVGASLFLPHGYLGIWAAVPFAIWFFLAVEGVPLAAE
EAKDPAKSLPRGLIGAMLILTAFGMLILFLGAGAAGASTLQNSGAPLVDALVKVYGTNTWLATFVNFVGLAGLIASFFSI
IYAYSRQIFALSRAGYLPTSLSLTNKNKAPYLAIIIPGIIGFLLSLTKEGDSLILIAVFGATISYVLILLSHIKLRLSKP
DMPRPYKTPGGIITSSIALVLAVAAVVAGFVVNPKVWFIAAGIYVVFIAYFLFYSRYHLVKGTPEEEFANIKAAEQEL

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI7657683, Length=346, Percent_Identity=26.0115606936416, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786302, Length=400, Percent_Identity=25, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790653, Length=389, Percent_Identity=24.6786632390745, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786602, Length=351, Percent_Identity=23.9316239316239, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082250, Length=287, Percent_Identity=22.9965156794425, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=352, Percent_Identity=24.4318181818182, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322892, Length=463, Percent_Identity=22.8941684665227, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668806, Length=401, Percent_Identity=24.6882793017456, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21356285, Length=401, Percent_Identity=24.6882793017456, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24668802, Length=401, Percent_Identity=24.6882793017456, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221512776, Length=398, Percent_Identity=25.3768844221106, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666159, Length=398, Percent_Identity=25.3768844221106, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24667468, Length=395, Percent_Identity=24.0506329113924, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50568; Mature: 50568

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPETASVISSSAEVSSAEYFAQRQLKQGTVGWLLLIGLGVAYVISGDFAGWNFGIAQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GWGGMFIATALAALMYLCLCLSMSEMSTMMPTAGGGYSFARAAFGPFGGYLTGTAILIEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
AIAPAAIAVFIGGYCESLFGINGWMIYLACYAIFMGIHLKGAGEALKIMFAITLVAAVAL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VVFIGAMIPHFNAQNLFDIPVSTGVGASLFLPHGYLGIWAAVPFAIWFFLAVEGVPLAAE
HHHHHHHCCCCCCCCEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
EAKDPAKSLPRGLIGAMLILTAFGMLILFLGAGAAGASTLQNSGAPLVDALVKVYGTNTW
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCCHH
LATFVNFVGLAGLIASFFSIIYAYSRQIFALSRAGYLPTSLSLTNKNKAPYLAIIIPGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEHHHHHH
GFLLSLTKEGDSLILIAVFGATISYVLILLSHIKLRLSKPDMPRPYKTPGGIITSSIALV
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
LAVAAVVAGFVVNPKVWFIAAGIYVVFIAYFLFYSRYHLVKGTPEEEFANIKAAEQEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHCCC
>Mature Secondary Structure
MNQPETASVISSSAEVSSAEYFAQRQLKQGTVGWLLLIGLGVAYVISGDFAGWNFGIAQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GWGGMFIATALAALMYLCLCLSMSEMSTMMPTAGGGYSFARAAFGPFGGYLTGTAILIEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
AIAPAAIAVFIGGYCESLFGINGWMIYLACYAIFMGIHLKGAGEALKIMFAITLVAAVAL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VVFIGAMIPHFNAQNLFDIPVSTGVGASLFLPHGYLGIWAAVPFAIWFFLAVEGVPLAAE
HHHHHHHCCCCCCCCEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
EAKDPAKSLPRGLIGAMLILTAFGMLILFLGAGAAGASTLQNSGAPLVDALVKVYGTNTW
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCCHH
LATFVNFVGLAGLIASFFSIIYAYSRQIFALSRAGYLPTSLSLTNKNKAPYLAIIIPGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEHHHHHH
GFLLSLTKEGDSLILIAVFGATISYVLILLSHIKLRLSKPDMPRPYKTPGGIITSSIALV
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
LAVAAVVAGFVVNPKVWFIAAGIYVVFIAYFLFYSRYHLVKGTPEEEFANIKAAEQEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]