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The map label for this gene is eutG [H]

Identifier: 213158425

GI number: 213158425

Start: 2458000

End: 2459157

Strand: Direct

Name: eutG [H]

Synonym: AB57_2374

Alternate gene names: 213158425

Gene position: 2458000-2459157 (Clockwise)

Preceding gene: 213158419

Following gene: 213158426

Centisome position: 60.68

GC content: 40.24

Gene sequence:

>1158_bases
ATGAGCCATTTTCAATTTCAGACCGTTCCCAACATTATTTCAGGACTCGGTTCTATACAAGAATTACAGAATGTGTTGGC
ATCAAAAACTTACCGCAAGTTATTATTGGTAACTGATGCGGGTATGATTAAAAATCAGTTACACCTGCCTATTCTTCAAA
TTTTAGATACTCTTAAAATTGAACATGTCATTTATGCTGATGTTCAGGCCGACCCACCAGAGCAAGTGGTATTAGATGCA
GCAAATTATGCTAAACAGCAAAATGTAGATGTTATTGTCGGCTTTGGAGGCGGAAGTTCTTTAGATGTAGCCAAAGTGAT
TGCCTTACTCGCACATCCCAACCAAACTCAAAACCTACAAGAAATGTACGGGATAAATCAGGTCAAAACAGCCCGACTTC
CACTTATTTTAATTCCCACTACAGCCGGTACTGGCTCGGAAGTGACACCCATATCAATAGTGACTACAGGTGAAACGACA
AAAATGGGAATTGTCTCTCCGGTACTCTATGCCGATACAGCAATTCTTGATGCAACTTTTACTCAAAATCTACCTGCCCA
TATTACGGCTGCTACAGGTATTGATGCGATGGTCCATGCCATTGAGGCATATACCTCTAAACATAAGAAAAATATTTATA
CCGATATTTTAGCGAAACACGCTTTAAAGCTACTGAACCATAACTTACCGAAAGTTCTTAAAAACGGTAATGATTTAGAG
GCACGTCAGAACATGCTGTTCGGCTCAATGCTTGCGGGTCAGGCATTTGCAAACTCACCTGTTGCTGCCGTGCATGCTTT
AGCCTATCCATTAGGTGGACATTTTCATTTGTCGCATGGACATACCAATGCTTTGGTGCTCGTTGAAGTACTGAAATTTA
ATGCGCCCTATGCCAAACAATACTATGCAGAACTTATGCAATGGCTAGACCCATATAGTAATGGCAGCACCGATGGTTTG
TGTGATCTATTTATTGACCATATGCAAAATCACTTAGACCGTAGTGGTTTGACTTTAAAACTTAGCGATTTGAGTATTGA
AGAGTCTAGCTTACCAAGACTTGCTCAAGATGCCATGTTGCAAACTCGATTACTGCAAAATAATCCACGTGACATGACAG
AAGCAGCTGCTTTAGCAATTTATCAGGCGATTTATTAA

Upstream 100 bases:

>100_bases
TAAATGCAGCTTAAAAGCACAGCTACTTTTAAGAGAATTTGCAGAATGAATCCTATAGAATGCATCTATAATAATTTTCA
AAAATAAGGAAATAATGTAT

Downstream 100 bases:

>100_bases
TGACTAAACCCGTTTTAAAAACTCGTGATCAATTTAAATTCTTTTTAGATATTCAAACTCGCTGGGCAGATAATGATATT
TACGGTCATGTGAATAATGT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSHFQFQTVPNIISGLGSIQELQNVLASKTYRKLLLVTDAGMIKNQLHLPILQILDTLKIEHVIYADVQADPPEQVVLDA
ANYAKQQNVDVIVGFGGGSSLDVAKVIALLAHPNQTQNLQEMYGINQVKTARLPLILIPTTAGTGSEVTPISIVTTGETT
KMGIVSPVLYADTAILDATFTQNLPAHITAATGIDAMVHAIEAYTSKHKKNIYTDILAKHALKLLNHNLPKVLKNGNDLE
ARQNMLFGSMLAGQAFANSPVAAVHALAYPLGGHFHLSHGHTNALVLVEVLKFNAPYAKQYYAELMQWLDPYSNGSTDGL
CDLFIDHMQNHLDRSGLTLKLSDLSIEESSLPRLAQDAMLQTRLLQNNPRDMTEAAALAIYQAIY

Sequences:

>Translated_385_residues
MSHFQFQTVPNIISGLGSIQELQNVLASKTYRKLLLVTDAGMIKNQLHLPILQILDTLKIEHVIYADVQADPPEQVVLDA
ANYAKQQNVDVIVGFGGGSSLDVAKVIALLAHPNQTQNLQEMYGINQVKTARLPLILIPTTAGTGSEVTPISIVTTGETT
KMGIVSPVLYADTAILDATFTQNLPAHITAATGIDAMVHAIEAYTSKHKKNIYTDILAKHALKLLNHNLPKVLKNGNDLE
ARQNMLFGSMLAGQAFANSPVAAVHALAYPLGGHFHLSHGHTNALVLVEVLKFNAPYAKQYYAELMQWLDPYSNGSTDGL
CDLFIDHMQNHLDRSGLTLKLSDLSIEESSLPRLAQDAMLQTRLLQNNPRDMTEAAALAIYQAIY
>Mature_384_residues
SHFQFQTVPNIISGLGSIQELQNVLASKTYRKLLLVTDAGMIKNQLHLPILQILDTLKIEHVIYADVQADPPEQVVLDAA
NYAKQQNVDVIVGFGGGSSLDVAKVIALLAHPNQTQNLQEMYGINQVKTARLPLILIPTTAGTGSEVTPISIVTTGETTK
MGIVSPVLYADTAILDATFTQNLPAHITAATGIDAMVHAIEAYTSKHKKNIYTDILAKHALKLLNHNLPKVLKNGNDLEA
RQNMLFGSMLAGQAFANSPVAAVHALAYPLGGHFHLSHGHTNALVLVEVLKFNAPYAKQYYAELMQWLDPYSNGSTDGLC
DLFIDHMQNHLDRSGLTLKLSDLSIEESSLPRLAQDAMLQTRLLQNNPRDMTEAAALAIYQAIY

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=418, Percent_Identity=26.555023923445, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI87082107, Length=380, Percent_Identity=31.0526315789474, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=31.7460317460317, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789163, Length=380, Percent_Identity=26.8421052631579, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787493, Length=371, Percent_Identity=29.3800539083558, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789386, Length=403, Percent_Identity=28.287841191067, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17537053, Length=264, Percent_Identity=29.5454545454545, Blast_Score=111, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321181, Length=383, Percent_Identity=33.9425587467363, Blast_Score=183, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24657991, Length=415, Percent_Identity=27.2289156626506, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 41988; Mature: 41857

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHFQFQTVPNIISGLGSIQELQNVLASKTYRKLLLVTDAGMIKNQLHLPILQILDTLKI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCHHHHHHHCHHHHHHHHHHHH
EHVIYADVQADPPEQVVLDAANYAKQQNVDVIVGFGGGSSLDVAKVIALLAHPNQTQNLQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHH
EMYGINQVKTARLPLILIPTTAGTGSEVTPISIVTTGETTKMGIVSPVLYADTAILDATF
HHHCCCHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEHHH
TQNLPAHITAATGIDAMVHAIEAYTSKHKKNIYTDILAKHALKLLNHNLPKVLKNGNDLE
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
ARQNMLFGSMLAGQAFANSPVAAVHALAYPLGGHFHLSHGHTNALVLVEVLKFNAPYAKQ
HHHHHHHHHHHHCHHHCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCHHHH
YYAELMQWLDPYSNGSTDGLCDLFIDHMQNHLDRSGLTLKLSDLSIEESSLPRLAQDAML
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCHHHHHHHHH
QTRLLQNNPRDMTEAAALAIYQAIY
HHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHFQFQTVPNIISGLGSIQELQNVLASKTYRKLLLVTDAGMIKNQLHLPILQILDTLKI
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCHHHHHHHCHHHHHHHHHHHH
EHVIYADVQADPPEQVVLDAANYAKQQNVDVIVGFGGGSSLDVAKVIALLAHPNQTQNLQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHH
EMYGINQVKTARLPLILIPTTAGTGSEVTPISIVTTGETTKMGIVSPVLYADTAILDATF
HHHCCCHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEHHH
TQNLPAHITAATGIDAMVHAIEAYTSKHKKNIYTDILAKHALKLLNHNLPKVLKNGNDLE
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
ARQNMLFGSMLAGQAFANSPVAAVHALAYPLGGHFHLSHGHTNALVLVEVLKFNAPYAKQ
HHHHHHHHHHHHCHHHCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCHHHH
YYAELMQWLDPYSNGSTDGLCDLFIDHMQNHLDRSGLTLKLSDLSIEESSLPRLAQDAML
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCHHHHHHHHH
QTRLLQNNPRDMTEAAALAIYQAIY
HHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868611; 10464203; 11677609 [H]