Click here to switch to the map view.

The map label for this gene is hcaT [H]

Identifier: 213158414

GI number: 213158414

Start: 2445477

End: 2446568

Strand: Reverse

Name: hcaT [H]

Synonym: AB57_2362

Alternate gene names: 213158414

Gene position: 2446568-2445477 (Counterclockwise)

Preceding gene: 213158415

Following gene: 213158413

Centisome position: 60.4

GC content: 37.09

Gene sequence:

>1092_bases
ATGCCGTATTGGAACTTATATCTCCAAGATCAGGGATTTAATTATCAAGAGATAGGTATTTTATCTTCTATTGCTATTGT
GACGCGCTTCTTTGCCCCTTTGGTTTGGGGCTGGATCGCCGATAAATCCGGTAAAAGAATGCTATTAGTGCGGATTGCCA
CATGGATGGAGGCATGTATATGGTTGGCTATTTTTATAATTCCTAATACTTTTCAGTCAGTTGCTTTATTGATGCTTATT
TTTAGTTTTTTCCAAAATGCTATTTTAGCTCAATTTGAAGGAGTAACTTTATTTTGGTTAGGAGACCAAAGGGCGAAACT
TTATGGCAAGATTCGAAAATGGGGATCAGTTGGGTTTATTGTAGGTGTATTTATAATAGGGGCAATTTTAGAAATCATTC
CGATTTCAATGTTGCCTATATTATTGCTTATCATTGCCTCATTAGCATTTATTTGGGCATTTACGATACGTGAACCAGAA
GGGGCCCCAACTTCACAAAAGCATTTAGAACCTTTATTACCCGTGCTGAAACGTCCTGAAGTTGCTGCTTTTTTCACAAT
TGAGTTTATTCTTCTTTTTTCACATGCACCTTTTTATAGCTTCTATAGCAATTTTCTGAAATCGTTAAGTTTTAGTACAA
CGGAAATTGGCTTTTTATGGGCTATGGGCGTGGTTTCTGAAATTGTGATGTTTGCATATGCAGCTACGTTTTTTAAATAT
TTTTCATGGCGTAGTCTTGTAGCAGTATGTTTGATTTTGACAAGTATACGTTGGTTATTAGTTGCTATTTTCTCTCACTA
TTTTATAGGTCAGTTATTTGCACAGTGCCTACACGCTTTTAGTTTTGGCTTATTTCATCTCATCGCAATGCGGCTTATCT
TTCAAAACTTTTCAATAGGGCAACAAGGTCGAGGTCAGGCTTTTTATAGCACCATGTGGGGGCTTGGAGTGGCGTTTGGG
AGCATTTTGGCTGGTCATTACTGGAAAATTCTTACGGGTGAGCATATTTTTATGATCGCTGCTTTAGTGGTTCTATTTGG
TTTGTGCTTTGTCTATTGGTTACCTAAACAAATCGAAAAGTCAGTTTCTTAG

Upstream 100 bases:

>100_bases
TATTGAAAGTACAAAGGTTTAAGTCTTGTTCCAACCATTTACAATCCAAACCAGATTAGGCGGATTCTACTTCTTTTATT
ATTCCATTGTTGGCACATTT

Downstream 100 bases:

>100_bases
ATTAAATAGTGATAAAAATTGTTAGGAATACCGAGTTAAAGATAGAAATTGTTTGATGAGAAGTATTGGTTCGTTACGGT
TGAAAAATATTGTTTTTATA

Product: metabolite transporter, MFS superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MPYWNLYLQDQGFNYQEIGILSSIAIVTRFFAPLVWGWIADKSGKRMLLVRIATWMEACIWLAIFIIPNTFQSVALLMLI
FSFFQNAILAQFEGVTLFWLGDQRAKLYGKIRKWGSVGFIVGVFIIGAILEIIPISMLPILLLIIASLAFIWAFTIREPE
GAPTSQKHLEPLLPVLKRPEVAAFFTIEFILLFSHAPFYSFYSNFLKSLSFSTTEIGFLWAMGVVSEIVMFAYAATFFKY
FSWRSLVAVCLILTSIRWLLVAIFSHYFIGQLFAQCLHAFSFGLFHLIAMRLIFQNFSIGQQGRGQAFYSTMWGLGVAFG
SILAGHYWKILTGEHIFMIAALVVLFGLCFVYWLPKQIEKSVS

Sequences:

>Translated_363_residues
MPYWNLYLQDQGFNYQEIGILSSIAIVTRFFAPLVWGWIADKSGKRMLLVRIATWMEACIWLAIFIIPNTFQSVALLMLI
FSFFQNAILAQFEGVTLFWLGDQRAKLYGKIRKWGSVGFIVGVFIIGAILEIIPISMLPILLLIIASLAFIWAFTIREPE
GAPTSQKHLEPLLPVLKRPEVAAFFTIEFILLFSHAPFYSFYSNFLKSLSFSTTEIGFLWAMGVVSEIVMFAYAATFFKY
FSWRSLVAVCLILTSIRWLLVAIFSHYFIGQLFAQCLHAFSFGLFHLIAMRLIFQNFSIGQQGRGQAFYSTMWGLGVAFG
SILAGHYWKILTGEHIFMIAALVVLFGLCFVYWLPKQIEKSVS
>Mature_362_residues
PYWNLYLQDQGFNYQEIGILSSIAIVTRFFAPLVWGWIADKSGKRMLLVRIATWMEACIWLAIFIIPNTFQSVALLMLIF
SFFQNAILAQFEGVTLFWLGDQRAKLYGKIRKWGSVGFIVGVFIIGAILEIIPISMLPILLLIIASLAFIWAFTIREPEG
APTSQKHLEPLLPVLKRPEVAAFFTIEFILLFSHAPFYSFYSNFLKSLSFSTTEIGFLWAMGVVSEIVMFAYAATFFKYF
SWRSLVAVCLILTSIRWLLVAIFSHYFIGQLFAQCLHAFSFGLFHLIAMRLIFQNFSIGQQGRGQAFYSTMWGLGVAFGS
ILAGHYWKILTGEHIFMIAALVVLFGLCFVYWLPKQIEKSVS

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=357, Percent_Identity=26.6106442577031, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 41413; Mature: 41282

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYWNLYLQDQGFNYQEIGILSSIAIVTRFFAPLVWGWIADKSGKRMLLVRIATWMEACI
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
WLAIFIIPNTFQSVALLMLIFSFFQNAILAQFEGVTLFWLGDQRAKLYGKIRKWGSVGFI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCHHHH
VGVFIIGAILEIIPISMLPILLLIIASLAFIWAFTIREPEGAPTSQKHLEPLLPVLKRPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
VAAFFTIEFILLFSHAPFYSFYSNFLKSLSFSTTEIGFLWAMGVVSEIVMFAYAATFFKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSWRSLVAVCLILTSIRWLLVAIFSHYFIGQLFAQCLHAFSFGLFHLIAMRLIFQNFSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QQGRGQAFYSTMWGLGVAFGSILAGHYWKILTGEHIFMIAALVVLFGLCFVYWLPKQIEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVS
CCC
>Mature Secondary Structure 
PYWNLYLQDQGFNYQEIGILSSIAIVTRFFAPLVWGWIADKSGKRMLLVRIATWMEACI
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
WLAIFIIPNTFQSVALLMLIFSFFQNAILAQFEGVTLFWLGDQRAKLYGKIRKWGSVGFI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCHHHH
VGVFIIGAILEIIPISMLPILLLIIASLAFIWAFTIREPEGAPTSQKHLEPLLPVLKRPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
VAAFFTIEFILLFSHAPFYSFYSNFLKSLSFSTTEIGFLWAMGVVSEIVMFAYAATFFKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSWRSLVAVCLILTSIRWLLVAIFSHYFIGQLFAQCLHAFSFGLFHLIAMRLIFQNFSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QQGRGQAFYSTMWGLGVAFGSILAGHYWKILTGEHIFMIAALVVLFGLCFVYWLPKQIEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]