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The map label for this gene is lpxA [H]

Identifier: 213158364

GI number: 213158364

Start: 2394199

End: 2394987

Strand: Reverse

Name: lpxA [H]

Synonym: AB57_2310

Alternate gene names: 213158364

Gene position: 2394987-2394199 (Counterclockwise)

Preceding gene: 213158365

Following gene: 213158358

Centisome position: 59.13

GC content: 36.88

Gene sequence:

>789_bases
ATGAGCAATCACGATTTAATCCATTCTACCGCCATTATTGATCCATCTGCAGTGATTGCTTCAGATGTTCAAATAGGACC
TTATTGTATTATCGGTCCTCAAGTGACTATTGGTGCTGGTACTAAATTACATTCTCATGTGGTTGTAGGTGGTTTTACCA
GAATTGGCCAAAATAACGAAATCTTTCAATTTGCAAGTGTTGGCGAAGTTTGCCAAGACCTCAAATATAAAGGTGAAGAA
ACGTGGCTTGAAATTGGTAACAATAATCTAATTCGCGAACATTGCAGCTTACATAGAGGTACGGTGCAAGATAATGCATT
AACCAAGATAGGTAGTCATAACCTATTAATGGTAAATACACATATTGCACATGATTGTATCGTAGGTGACCATAATATCT
TTGCTAATAATGTAGGTGTCGCTGGACATGTACATATTGGTGATCACGTTATTGTGGGTGGTAATTCTGGAATTCATCAA
TTCTGTAAGATCGATTCTTATAGCATGATTGGTGGGGCTTCTTTGATCCTTAAAGATGTTCCAGCCTATGTGATGGCTTC
TGGTAACCCTGCACATGCGTTTGGTATAAATATTGAAGGTATGCGAAGAAAAGGTTGGTCTAAAAATACAATTCAAGGCT
TAAGAGAAGCTTATAAATTGATATTTAAATCTGGATTAACTTCTGTTCAAGCTATTGACCAAATTAAAAGTGAAATTTTA
CCTTCAGTTCCAGAAGCTCAACTCTTGATTGATTCTCTTGAACAATCAGAGCGTGGAATTGTGCGCTAA

Upstream 100 bases:

>100_bases
AGAAGCGCGGTATCTACAAATACAATTGTACAGCTAGCGTTGACGGCATTGTAGCAGCAACCGCTGAGATTATGATTTCA
CACCAAAAAACAGAGCAGGC

Downstream 100 bases:

>100_bases
TTAAGAAGACATAAAAAAAGACACTGTTTTAACAGTGTCTTTTTTTATAACTAAATTATTTGTTAAAGAATTTTGCTTCT
TCAGATTTTGGATATTGGCT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVGEVCQDLKYKGEE
TWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQ
FCKIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEIL
PSVPEAQLLIDSLEQSERGIVR

Sequences:

>Translated_262_residues
MSNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVGEVCQDLKYKGEE
TWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQ
FCKIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEIL
PSVPEAQLLIDSLEQSERGIVR
>Mature_261_residues
SNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVGEVCQDLKYKGEET
WLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQF
CKIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEILP
SVPEAQLLIDSLEQSERGIVR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=260, Percent_Identity=52.6923076923077, Blast_Score=286, Evalue=8e-79,
Organism=Escherichia coli, GI1786376, Length=223, Percent_Identity=26.0089686098655, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28284; Mature: 28152

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNE
CCCCCCEEEEEEECCHHHHCCCCCCCCEEEECCEEEECCCCEEECEEEEECEEECCCCCC
IFQFASVGEVCQDLKYKGEETWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNT
EEEHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEC
HIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQFCKIDSYSMIGGASLILKDV
CCCCEEEECCCCEEECCCCEEEEEEECCEEEECCCCCHHHHHCCCCCCCCCCHHHHHHCC
PAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEIL
CEEEEECCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
PSVPEAQLLIDSLEQSERGIVR
CCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNE
CCCCCEEEEEEECCHHHHCCCCCCCCEEEECCEEEECCCCEEECEEEEECEEECCCCCC
IFQFASVGEVCQDLKYKGEETWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNT
EEEHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEC
HIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQFCKIDSYSMIGGASLILKDV
CCCCEEEECCCCEEECCCCEEEEEEECCEEEECCCCCHHHHHCCCCCCCCCCHHHHHHCC
PAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEIL
CEEEEECCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
PSVPEAQLLIDSLEQSERGIVR
CCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA