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The map label for this gene is htpX [H]

Identifier: 213158343

GI number: 213158343

Start: 3168284

End: 3169189

Strand: Direct

Name: htpX [H]

Synonym: AB57_3073

Alternate gene names: 213158343

Gene position: 3168284-3169189 (Clockwise)

Preceding gene: 213158342

Following gene: 213158346

Centisome position: 78.22

GC content: 44.15

Gene sequence:

>906_bases
ATGATGCGGATTGGTTTGTTTTTGCTTACCAACCTCGCGGTACTGGTTGTAGCTGGCATTATTTTGTCACTCTTCGGTGT
CGGTAGTTACCATGGCGCGGGTGGCTTAAATCTAGGCAACCTTTTAGTCATCTGTTTTGTGTTCGGTATGGTGGGCTCTT
TAGTCTCTCTATTCATGTCCAAATGGATGGCTAAGAAAACTACTGGTACAGAACTGATTGACCCAAATGCTCCTCGTAAC
CAAGCTGAAAGCTGGTTATTGCAAACAGTCGCTGAACTTTCTCAACGTGCTGGTATTAATATGCCAGAAGTTGGTATCTT
CCCTTCATATCAGTCTAATGCCTTTGCAACAGGCTGGAATAAAAATGATGCCTTAGTTGCCGTTTCAAGCGGTCTACTTG
AGCGTATGAACAAAGATGAGCTACGTGCTGTGCTCGCGCACGAGATCGGCCACGTTGCAAATGGTGACATGGTTACACTC
GCACTCATTCAAGGTGTAGTAAACGCCTTCGTTATGTTCTTTGCTCGTGTAGTAGGTGACTTTATTGACCGTAATGTCTT
TGGTCGTCAAGACAATGAAGCCCCAGGTATGGGTTATTTCATCATTACAATGGTTCTAGATATCGTGTTCGGTATTCTTG
CCTCTGCCATTGTGATGTGGTTCTCTCGTTACCGTGAATACCGTGCAGATGAAGCCGGTGCGCGTTTAGCTGGTAAACAA
GCAATGATTTCTGCTTTATTACGTTTGCAAGCTGAAACAGAGTTACCTGACCAAATGCCAAAAGAAATGAAAGCATTCGC
AATTGCGGAAGGTAAAGAACAAGGCTTTAGTTTAGCTGCATTGTTCCAAACTCACCCTACAATTGAACAACGTGTGGCAG
CTCTACACCAATTAGATTGCCCATAA

Upstream 100 bases:

>100_bases
TTATTTTTTTCTTGAATTTTTCCCCTAAGCGCCGCATATTAGCTGAGTGATTTATAATTTATAAATCAGATAATATTTTA
TTTATAAGAGGATTTTCTCA

Downstream 100 bases:

>100_bases
AACGTTTAATGTAAAAATAAAGCCTCCAAATGGAGGCTTTATTTTTTGATTACATGGTTTGATAAAGTCCCCAAAGGTAA
CTTGCACCCCACCACACAGC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMSKWMAKKTTGTELIDPNAPRN
QAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWNKNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTL
ALIQGVVNAFVMFFARVVGDFIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQ
AMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDCP

Sequences:

>Translated_301_residues
MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMSKWMAKKTTGTELIDPNAPRN
QAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWNKNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTL
ALIQGVVNAFVMFFARVVGDFIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQ
AMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDCP
>Mature_301_residues
MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMSKWMAKKTTGTELIDPNAPRN
QAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWNKNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTL
ALIQGVVNAFVMFFARVVGDFIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQ
AMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDCP

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=300, Percent_Identity=49, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 32820; Mature: 32820

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KWMAKKTTGTELIDPNAPRNQAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWN
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCC
KNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTLALIQGVVNAFVMFFARVVGD
CCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQ
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
AMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDC
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCHHHHHHHHHHCCC
P
C
>Mature Secondary Structure
MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KWMAKKTTGTELIDPNAPRNQAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWN
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCC
KNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTLALIQGVVNAFVMFFARVVGD
CCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQ
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
AMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDC
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCHHHHHHHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA