Click here to switch to the map view.

The map label for this gene is mltF [H]

Identifier: 213158339

GI number: 213158339

Start: 3164125

End: 3165072

Strand: Direct

Name: mltF [H]

Synonym: AB57_3069

Alternate gene names: 213158339

Gene position: 3164125-3165072 (Clockwise)

Preceding gene: 213158337

Following gene: 213158342

Centisome position: 78.12

GC content: 41.56

Gene sequence:

>948_bases
GTGGTTGCCGTAGAAAGCCCAACGACTGTTTTTAAAGAAGACCAGTTTTTACACGGCTTCGGTTATGACTTAGCGCGTAA
CTATGCACAAAGCTTAAATGTAAAGTTGGACTTCAAAATCGTGACAGATAATGCCACGGCGCTTAAGTGGGTTCAGCAAG
GTAAAGCAAATCTTGCCATGACAACCGCAAGCTTAAGTTCAATCGAGAACAAAGGTTTAATGTCTTTTTCTGCAAGTTGT
GGTGATATCGTAAATTTGCAAAAAAATGGATTAAATCCGAATCTAAGCTGGGTGTTTAAACAAGCAGATGACCCGCTTAC
ACAAACAGCAAGCGGTTTTGTTTGTCAAAGCAAACAAAATGGCCTAACTCAGCAACTTGCTTCTTTTTATAACCGTAATG
TTGTAAAACCAGAAGCTTGGTCTACGATTCAACGTGACTTAAGTGCACGTATACCGATTTACAAAGCAAGCTTTAAACAA
AGTGCTGCTCAGTACGATTTAGACTGGCATTTGCTTGCAGCGATTGGTTATCAAGAATCGTACCTAAAGCCAGAGTCTGT
TTCACCAACAGGTGTACGTGGGTTAATGATGTTAACCAATAGTACAGCTCGGGCAATGGGTGTAAGTAACCGTAACGATC
CAGCACAGAGTATTCAGGGCGGTGCGAAATATTATGATCTCATGTTAAGTGAGTATGATGATATTCCTTTCCCTGATCGC
AACTGGTATGCACTTGTGGCTTACAATATGGGACCGGGTGCGGTGAACCAGATTCAAAAGCGCTTGCAAGCCCAAGGGAA
AGACCCGAACCAATGGGTTAATCTCTATAATTATTTGCAGAGTAACAAAACTCGCAATGGTCGATACAAACAAGCAGTTC
AGTATGTGACTCGTATACGTGCTTATCTTGAGCACATTAAAACGGCACAAACGCGAATTAATATCTAG

Upstream 100 bases:

>100_bases
GAAAGTTCTTGCGCTCAGCACTATGTTTTTTCCCTTTCATAGTATCAATGCAGGAAAAACCCTACAGTACAATACTGTAG
TTAACACAAACACATTAACA

Downstream 100 bases:

>100_bases
TTTTTATCATCTAAAAGTTGATAAATTCATTGTTTGTATAAATAAAAAGCTTACCTCTCGGGTAAGCTTTTTATATGAAT
TCTTTTTTAGTTTAAGCGGT

Product: lytic transglycosylase, catalytic

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MVAVESPTTVFKEDQFLHGFGYDLARNYAQSLNVKLDFKIVTDNATALKWVQQGKANLAMTTASLSSIENKGLMSFSASC
GDIVNLQKNGLNPNLSWVFKQADDPLTQTASGFVCQSKQNGLTQQLASFYNRNVVKPEAWSTIQRDLSARIPIYKASFKQ
SAAQYDLDWHLLAAIGYQESYLKPESVSPTGVRGLMMLTNSTARAMGVSNRNDPAQSIQGGAKYYDLMLSEYDDIPFPDR
NWYALVAYNMGPGAVNQIQKRLQAQGKDPNQWVNLYNYLQSNKTRNGRYKQAVQYVTRIRAYLEHIKTAQTRINI

Sequences:

>Translated_315_residues
MVAVESPTTVFKEDQFLHGFGYDLARNYAQSLNVKLDFKIVTDNATALKWVQQGKANLAMTTASLSSIENKGLMSFSASC
GDIVNLQKNGLNPNLSWVFKQADDPLTQTASGFVCQSKQNGLTQQLASFYNRNVVKPEAWSTIQRDLSARIPIYKASFKQ
SAAQYDLDWHLLAAIGYQESYLKPESVSPTGVRGLMMLTNSTARAMGVSNRNDPAQSIQGGAKYYDLMLSEYDDIPFPDR
NWYALVAYNMGPGAVNQIQKRLQAQGKDPNQWVNLYNYLQSNKTRNGRYKQAVQYVTRIRAYLEHIKTAQTRINI
>Mature_315_residues
MVAVESPTTVFKEDQFLHGFGYDLARNYAQSLNVKLDFKIVTDNATALKWVQQGKANLAMTTASLSSIENKGLMSFSASC
GDIVNLQKNGLNPNLSWVFKQADDPLTQTASGFVCQSKQNGLTQQLASFYNRNVVKPEAWSTIQRDLSARIPIYKASFKQ
SAAQYDLDWHLLAAIGYQESYLKPESVSPTGVRGLMMLTNSTARAMGVSNRNDPAQSIQGGAKYYDLMLSEYDDIPFPDR
NWYALVAYNMGPGAVNQIQKRLQAQGKDPNQWVNLYNYLQSNKTRNGRYKQAVQYVTRIRAYLEHIKTAQTRINI

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=171, Percent_Identity=37.4269005847953, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 35384; Mature: 35384

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVESPTTVFKEDQFLHGFGYDLARNYAQSLNVKLDFKIVTDNATALKWVQQGKANLAM
CCCCCCCCHHHCCCCHHHHCCHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHCCCCCEEE
TTASLSSIENKGLMSFSASCGDIVNLQKNGLNPNLSWVFKQADDPLTQTASGFVCQSKQN
EHHHHHHHCCCCCEEECCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHCCCCEEECCCC
GLTQQLASFYNRNVVKPEAWSTIQRDLSARIPIYKASFKQSAAQYDLDWHLLAAIGYQES
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCEEEEEHHCCHHH
YLKPESVSPTGVRGLMMLTNSTARAMGVSNRNDPAQSIQGGAKYYDLMLSEYDDIPFPDR
CCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCC
NWYALVAYNMGPGAVNQIQKRLQAQGKDPNQWVNLYNYLQSNKTRNGRYKQAVQYVTRIR
CEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AYLEHIKTAQTRINI
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAVESPTTVFKEDQFLHGFGYDLARNYAQSLNVKLDFKIVTDNATALKWVQQGKANLAM
CCCCCCCCHHHCCCCHHHHCCHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHCCCCCEEE
TTASLSSIENKGLMSFSASCGDIVNLQKNGLNPNLSWVFKQADDPLTQTASGFVCQSKQN
EHHHHHHHCCCCCEEECCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHCCCCEEECCCC
GLTQQLASFYNRNVVKPEAWSTIQRDLSARIPIYKASFKQSAAQYDLDWHLLAAIGYQES
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCEEEEEHHCCHHH
YLKPESVSPTGVRGLMMLTNSTARAMGVSNRNDPAQSIQGGAKYYDLMLSEYDDIPFPDR
CCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCC
NWYALVAYNMGPGAVNQIQKRLQAQGKDPNQWVNLYNYLQSNKTRNGRYKQAVQYVTRIR
CEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AYLEHIKTAQTRINI
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA