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The map label for this gene is dhbF [H]

Identifier: 213158336

GI number: 213158336

Start: 3157697

End: 3161695

Strand: Reverse

Name: dhbF [H]

Synonym: AB57_3066

Alternate gene names: 213158336

Gene position: 3161695-3157697 (Counterclockwise)

Preceding gene: 213158338

Following gene: 213158331

Centisome position: 78.06

GC content: 41.39

Gene sequence:

>3999_bases
ATGAACCAGTTTGTAACGAACACGAAAAATGTAATTCGTGGAAAGTATCATCCGGAATTTTTGCAGAATGAAGTCTTAGC
CGATATTTTTGCTCATACTGCACAAACTCTTCCTGATAAAACGGCTTTAATTGAAGCAGATAAAACGCTGAGTTATGGTG
AGCTGTATCAGCAAGCCTTAATTATGGCTCAACATCTGGCTTTAAAAGGGGTAAAGCCGGGTCATATTGTAGGGCTATGG
TTGCCGCGTGGTATTGAGCTTTTAAAAGCTCAACTGGCCATTTGTTTAAGTGGTGCAGCTTGGCTTCCTTTTGATATGGA
TACGCCCGCGGACCGTATTGCGGTATGTCTTGAAGATGCCGAAGCAGTAGGAATGATTACTACAGATGAATGGTATGAAC
ATTTAGCTGAAGTGCCGCAAACAAAATGGACCAACACCGAGCTGCAAAAACCATTAAGCGAAAGTGTAAGTTTAGCGAAA
ACCACTCCAGATCAACCTGCCTATATTATTTATACCTCGGGTTCGACAGGTAAACCCAAAGGAATTGTGATTACTCAAAA
AAATATTTGTCACTTTTTACGTAGTGAAAATAGTATTTTGGGTATTCAAGAGCAAGACAAGGTCTATCAAGGCTTTTCAG
TCGCTTTTGATATGTCGTTTGAAGAGATTTGGCTTTCTTATTTGGTAGGTGCAACGTTGTGGATTGCACCGAAGTCACTT
GTCAGTGATCCTGAGCGGTTATGCCAAACCTTAAAGCAGGAACAAATTACAGTACTGCACGCTGTTCCAACGTTACTTGC
CTTATTTCCTGAAGACGTACCTAATTTAAGAATTATTAATTTAGGTGGGGAAATGTGTCCGGACTCACTGGTTGACCGCT
GGGCATTACCTCATCATCAAATGTTTAACACCTATGGACCAACCGAAACCACGGTTTCTGCAAGTCTTGAGTTATTAGAA
CGAGGCAAACCTGTCACCATTGGCAAGCCCTTACCAAACTACGGTATGTTGGTTATTAACTCTGAAAGAGAGTTGCTCGA
GCAAGGTGAAACAGGGGAGTTATGTATTTTTGGTCCAAGTGTGGCACAAGGCTATTTAGGACGACCTGATTTAACCGCAG
ATAAGTTTATTGAAAACCCTTGGGCAATGAGTGTAGAGGAAGAATTACTCTACCGTACTGGGGATTTGGCTAAAATTGAT
GAGTTTGGTCAAGTACACTGTTTAGGTCGTGCCGATGACCAAGTTAAAATCCGTGGTTTCCGTGTAGAGCTTGGCGAGAT
CGAAGCTGCGCTTTGCGATATTGACGGAATTGGTACGGCAGCCGTTATTCTTCGTCCTGAAGACGGCATTGATCAACTTA
TTGCGTTTATTGCACCAGAAATTGATGCAAAGCAAGCTATAGAAATTAAAGAACTACGCCATAACTTGAGTCAGCGATTA
CCGCCTTATATGGTGCCAAATCGTTTTGAGATTATTGAAGAAGTTCCACGTCTATTATCTGGGAAAATTGACCGTAAAGC
TTTAAAAGCAAGACCGCTCACAAGTGTGGTAGATCGCAGTGAATCTGACCAGCCACAGAACCCAGCCGAAGAAATCCTAT
TTGAAATTTTGAATCGCTTGTTCCCGAACATGCCGATTAAACTCGATTCCGATTTCTTTGATGATTTAGGCGGGCATTCA
CTACTCGCCGCTGTTTTAATTTCAAATCTGCGTGAGCATGCGGAATATAGCCATCTGACCATTCAAAACTTATATCAAGC
GAGAAGAGTAGGCGCGATTGCTGCACTCATGTTAGAGCAGCCTGAACCTACTTTATTTGATAGCCAAATTGGACAAGATA
ACCCTCGTAATCAGACTTATAAATGGTTATGTGGTATTGCCCAGCTCGTTACTATTCCAGTTTTAATCTCGATTAATATT
TTGCAGTGGTTAGCGCCATTCTTTACCTATCACTACTTTACCGGTGGAACTCGCGACAGTATTCCGTATGCGATTGCGTT
GTCTTTATTGGTGTATGTCAGTGTCATTATGAGCAGTTTTGTACTGTCGATTACGGTAAAACGACTATTAATGTTAGGAA
TTGGCGCAGGGCGTTATCCATTATGGGGATTAACCTATTTCCGTTGGTGGCTAGCAGACCGTATTAGTAATATTTCACCT
GTTTATCTTTTATCTGGTTCGACTTTACTTAACTTATATTTGAAAGCACTTGGCGCAAAAATCGGCCACGACGTTACCAT
TAGTTCCGTACATATTCGTATGCCATCTTTACTGACTATTGAAGATGGCGTGAGTATCGGTTCTCAGGTGAATTTAGAAA
ATGCCAAAGTTGAACATGGCCACTTGGTATTAGGTTCAATTCACCTTAAACAAGACAGTTATGTAGGTTCGTATGCTGTA
TTAGAAGAAAATACAGTGTTAGAAAAACAGGCCCATGTAAATGCCTTAACTTCAATTGAATATGACACGGTTGTACCTGA
GGGCGAAATTTGGGATGGAACACCTGCTCAGAAAATAGGGCATATAGATGAGCAAGCTAAATTGCCAGAGCGTCCTAAAC
TATCGTTTATACGTAAAATTGCTGAATATGGATACTATGGCGTTAGTGCATTAATTATTGCCTGTCTTTTCTTTATTCCA
ATTTTTCCTAGCTTCCTTTTGGTCGACTGGCTAGATGTAAATGTATTTAATATTAACCCGAACAACCATTTGCAAATCGC
GCTTTATTATTTCATTTTAGCGATTCCGGCTAGTGCAATGATGATGATGATTACTGCGGTGATTTCTTCAGGTCTACGTA
AAATTGCATTGCCGCGTCTTGAAATTGGAACCTATGCGGTTCATGGCAGTACGTATTATCGTAAATGGTTTGCGGCCCAA
ATTTTAGAAACGAGCTTACAAACCTTACATGGCTTGTTTGCCACCATTTATGCGCCTACATGGTTCCGTATGCTGGGAGC
AAAAGTGGGTAAAAATACCGAAATTTCTACCGCAACCGGCGTTATTCCAGAAATGCTGACTTTGGGTGAAGAGAGCTTTA
TTGCCGATGCTGTAATGCTGGGTGATGAAGAGATTAAAGGCGGTTGGATGTCTTTAAAAGCAACCAAAATCGGTAACCGT
AGTTTTGTGGGAAATAGTGCTTATATTGCTGATGGGACAGTGTTACCAGACAATGTTTTAATTGGCGTGCAATCAAAAAC
ACCAGATAACCGTGAAATGTATGATGGACAAACTTGGTTTGGTTCTCCGGCGTTGCTGTTACCTGCACGTGAAGCTGCTG
AAAAATATCCTGACCATTTAACCTTTAAACCAAGTATTAAGCGCCGTTTAATGCGCGGGTTTATTGAAGGGCTTCGTATT
GTATTGCCGGCCGCACTTGCGATTGGGGTGGGTTATATGATCGTGCTAGACGTTATTGATGTGATTAATAACTACAATAT
TGAGACGGGTCTGGTTGCATTAACGCTCGCAGGACTGCTTTATGGTGTTGGCTGTTTCCTTATTGTTGCGCTATTAAAGT
GGATTTTGATTGGTCGCTATCAACCGCGTTCGGCACCTATGTGGACCATGTTTGTATGGTTAAGTGAAGGGATTACCAGC
CTATATGAATCAGTTGCGATTCCTAACTTCTTAAACTACTTAAGAGGAACACCAATGTTGCCATTCTTCTTGCGTATTTT
AGGGGTTCGTATTGGTAAAGACGTTTATATGGATACGGCTGATATTACCGAGTTTGACTGTGTCAGCATTGGTGACCGTG
CCGAGTTTAATAGCTTTTCAGGCCCGCAAACTCACTTATTTGAAGACCGTATTATGAAAATTGGGCAAGTAAATGTTGGC
AATGATGTTGTGGTAAATACACGCAGTATTATTTTGTATAACGCCAACGTGAGCAACCATGCCGTATTAGGTCCATTAAC
ACTGGTCATGAAAGGTGAAAATATTCCGGCTAAATCTGCTTGGATTGGGTCACCAGCCGTACCTTGGGTTCATAAATAA

Upstream 100 bases:

>100_bases
CTCTTAATTAATTTATGGCCTATCTAGATTTCGTTAATGGGTCAGAAAAATAAATTATGACTTCATTTAAGCCAAATCAG
AAAATTAAGAGAGTATAAAA

Downstream 100 bases:

>100_bases
TTAAGTTTTCAATTAAAAAAGCCTCTGTAGAAACAGGGGCATTTTTTGTTTATATTTTTTCTTATTTATAAATCTAAATA
AAAATTCGGGTATAGGTAGT

Product: non-ribosomal peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1332; Mature: 1332

Protein sequence:

>1332_residues
MNQFVTNTKNVIRGKYHPEFLQNEVLADIFAHTAQTLPDKTALIEADKTLSYGELYQQALIMAQHLALKGVKPGHIVGLW
LPRGIELLKAQLAICLSGAAWLPFDMDTPADRIAVCLEDAEAVGMITTDEWYEHLAEVPQTKWTNTELQKPLSESVSLAK
TTPDQPAYIIYTSGSTGKPKGIVITQKNICHFLRSENSILGIQEQDKVYQGFSVAFDMSFEEIWLSYLVGATLWIAPKSL
VSDPERLCQTLKQEQITVLHAVPTLLALFPEDVPNLRIINLGGEMCPDSLVDRWALPHHQMFNTYGPTETTVSASLELLE
RGKPVTIGKPLPNYGMLVINSERELLEQGETGELCIFGPSVAQGYLGRPDLTADKFIENPWAMSVEEELLYRTGDLAKID
EFGQVHCLGRADDQVKIRGFRVELGEIEAALCDIDGIGTAAVILRPEDGIDQLIAFIAPEIDAKQAIEIKELRHNLSQRL
PPYMVPNRFEIIEEVPRLLSGKIDRKALKARPLTSVVDRSESDQPQNPAEEILFEILNRLFPNMPIKLDSDFFDDLGGHS
LLAAVLISNLREHAEYSHLTIQNLYQARRVGAIAALMLEQPEPTLFDSQIGQDNPRNQTYKWLCGIAQLVTIPVLISINI
LQWLAPFFTYHYFTGGTRDSIPYAIALSLLVYVSVIMSSFVLSITVKRLLMLGIGAGRYPLWGLTYFRWWLADRISNISP
VYLLSGSTLLNLYLKALGAKIGHDVTISSVHIRMPSLLTIEDGVSIGSQVNLENAKVEHGHLVLGSIHLKQDSYVGSYAV
LEENTVLEKQAHVNALTSIEYDTVVPEGEIWDGTPAQKIGHIDEQAKLPERPKLSFIRKIAEYGYYGVSALIIACLFFIP
IFPSFLLVDWLDVNVFNINPNNHLQIALYYFILAIPASAMMMMITAVISSGLRKIALPRLEIGTYAVHGSTYYRKWFAAQ
ILETSLQTLHGLFATIYAPTWFRMLGAKVGKNTEISTATGVIPEMLTLGEESFIADAVMLGDEEIKGGWMSLKATKIGNR
SFVGNSAYIADGTVLPDNVLIGVQSKTPDNREMYDGQTWFGSPALLLPAREAAEKYPDHLTFKPSIKRRLMRGFIEGLRI
VLPAALAIGVGYMIVLDVIDVINNYNIETGLVALTLAGLLYGVGCFLIVALLKWILIGRYQPRSAPMWTMFVWLSEGITS
LYESVAIPNFLNYLRGTPMLPFFLRILGVRIGKDVYMDTADITEFDCVSIGDRAEFNSFSGPQTHLFEDRIMKIGQVNVG
NDVVVNTRSIILYNANVSNHAVLGPLTLVMKGENIPAKSAWIGSPAVPWVHK

Sequences:

>Translated_1332_residues
MNQFVTNTKNVIRGKYHPEFLQNEVLADIFAHTAQTLPDKTALIEADKTLSYGELYQQALIMAQHLALKGVKPGHIVGLW
LPRGIELLKAQLAICLSGAAWLPFDMDTPADRIAVCLEDAEAVGMITTDEWYEHLAEVPQTKWTNTELQKPLSESVSLAK
TTPDQPAYIIYTSGSTGKPKGIVITQKNICHFLRSENSILGIQEQDKVYQGFSVAFDMSFEEIWLSYLVGATLWIAPKSL
VSDPERLCQTLKQEQITVLHAVPTLLALFPEDVPNLRIINLGGEMCPDSLVDRWALPHHQMFNTYGPTETTVSASLELLE
RGKPVTIGKPLPNYGMLVINSERELLEQGETGELCIFGPSVAQGYLGRPDLTADKFIENPWAMSVEEELLYRTGDLAKID
EFGQVHCLGRADDQVKIRGFRVELGEIEAALCDIDGIGTAAVILRPEDGIDQLIAFIAPEIDAKQAIEIKELRHNLSQRL
PPYMVPNRFEIIEEVPRLLSGKIDRKALKARPLTSVVDRSESDQPQNPAEEILFEILNRLFPNMPIKLDSDFFDDLGGHS
LLAAVLISNLREHAEYSHLTIQNLYQARRVGAIAALMLEQPEPTLFDSQIGQDNPRNQTYKWLCGIAQLVTIPVLISINI
LQWLAPFFTYHYFTGGTRDSIPYAIALSLLVYVSVIMSSFVLSITVKRLLMLGIGAGRYPLWGLTYFRWWLADRISNISP
VYLLSGSTLLNLYLKALGAKIGHDVTISSVHIRMPSLLTIEDGVSIGSQVNLENAKVEHGHLVLGSIHLKQDSYVGSYAV
LEENTVLEKQAHVNALTSIEYDTVVPEGEIWDGTPAQKIGHIDEQAKLPERPKLSFIRKIAEYGYYGVSALIIACLFFIP
IFPSFLLVDWLDVNVFNINPNNHLQIALYYFILAIPASAMMMMITAVISSGLRKIALPRLEIGTYAVHGSTYYRKWFAAQ
ILETSLQTLHGLFATIYAPTWFRMLGAKVGKNTEISTATGVIPEMLTLGEESFIADAVMLGDEEIKGGWMSLKATKIGNR
SFVGNSAYIADGTVLPDNVLIGVQSKTPDNREMYDGQTWFGSPALLLPAREAAEKYPDHLTFKPSIKRRLMRGFIEGLRI
VLPAALAIGVGYMIVLDVIDVINNYNIETGLVALTLAGLLYGVGCFLIVALLKWILIGRYQPRSAPMWTMFVWLSEGITS
LYESVAIPNFLNYLRGTPMLPFFLRILGVRIGKDVYMDTADITEFDCVSIGDRAEFNSFSGPQTHLFEDRIMKIGQVNVG
NDVVVNTRSIILYNANVSNHAVLGPLTLVMKGENIPAKSAWIGSPAVPWVHK
>Mature_1332_residues
MNQFVTNTKNVIRGKYHPEFLQNEVLADIFAHTAQTLPDKTALIEADKTLSYGELYQQALIMAQHLALKGVKPGHIVGLW
LPRGIELLKAQLAICLSGAAWLPFDMDTPADRIAVCLEDAEAVGMITTDEWYEHLAEVPQTKWTNTELQKPLSESVSLAK
TTPDQPAYIIYTSGSTGKPKGIVITQKNICHFLRSENSILGIQEQDKVYQGFSVAFDMSFEEIWLSYLVGATLWIAPKSL
VSDPERLCQTLKQEQITVLHAVPTLLALFPEDVPNLRIINLGGEMCPDSLVDRWALPHHQMFNTYGPTETTVSASLELLE
RGKPVTIGKPLPNYGMLVINSERELLEQGETGELCIFGPSVAQGYLGRPDLTADKFIENPWAMSVEEELLYRTGDLAKID
EFGQVHCLGRADDQVKIRGFRVELGEIEAALCDIDGIGTAAVILRPEDGIDQLIAFIAPEIDAKQAIEIKELRHNLSQRL
PPYMVPNRFEIIEEVPRLLSGKIDRKALKARPLTSVVDRSESDQPQNPAEEILFEILNRLFPNMPIKLDSDFFDDLGGHS
LLAAVLISNLREHAEYSHLTIQNLYQARRVGAIAALMLEQPEPTLFDSQIGQDNPRNQTYKWLCGIAQLVTIPVLISINI
LQWLAPFFTYHYFTGGTRDSIPYAIALSLLVYVSVIMSSFVLSITVKRLLMLGIGAGRYPLWGLTYFRWWLADRISNISP
VYLLSGSTLLNLYLKALGAKIGHDVTISSVHIRMPSLLTIEDGVSIGSQVNLENAKVEHGHLVLGSIHLKQDSYVGSYAV
LEENTVLEKQAHVNALTSIEYDTVVPEGEIWDGTPAQKIGHIDEQAKLPERPKLSFIRKIAEYGYYGVSALIIACLFFIP
IFPSFLLVDWLDVNVFNINPNNHLQIALYYFILAIPASAMMMMITAVISSGLRKIALPRLEIGTYAVHGSTYYRKWFAAQ
ILETSLQTLHGLFATIYAPTWFRMLGAKVGKNTEISTATGVIPEMLTLGEESFIADAVMLGDEEIKGGWMSLKATKIGNR
SFVGNSAYIADGTVLPDNVLIGVQSKTPDNREMYDGQTWFGSPALLLPAREAAEKYPDHLTFKPSIKRRLMRGFIEGLRI
VLPAALAIGVGYMIVLDVIDVINNYNIETGLVALTLAGLLYGVGCFLIVALLKWILIGRYQPRSAPMWTMFVWLSEGITS
LYESVAIPNFLNYLRGTPMLPFFLRILGVRIGKDVYMDTADITEFDCVSIGDRAEFNSFSGPQTHLFEDRIMKIGQVNVG
NDVVVNTRSIILYNANVSNHAVLGPLTLVMKGENIPAKSAWIGSPAVPWVHK

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI38505220, Length=501, Percent_Identity=25.1497005988024, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI45580730, Length=435, Percent_Identity=27.1264367816092, Blast_Score=114, Evalue=8e-25,
Organism=Homo sapiens, GI187761345, Length=529, Percent_Identity=24.952741020794, Blast_Score=114, Evalue=9e-25,
Organism=Homo sapiens, GI187761343, Length=529, Percent_Identity=24.952741020794, Blast_Score=114, Evalue=9e-25,
Organism=Homo sapiens, GI42544132, Length=476, Percent_Identity=25, Blast_Score=111, Evalue=6e-24,
Organism=Homo sapiens, GI115511026, Length=485, Percent_Identity=25.360824742268, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI122937307, Length=480, Percent_Identity=22.7083333333333, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI58082049, Length=481, Percent_Identity=23.2848232848233, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI157311624, Length=481, Percent_Identity=23.7006237006237, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI157311622, Length=481, Percent_Identity=23.7006237006237, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI28416953, Length=591, Percent_Identity=23.3502538071066, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI156151445, Length=561, Percent_Identity=22.1033868092692, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI13375727, Length=546, Percent_Identity=20.6959706959707, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI195947378, Length=279, Percent_Identity=25.4480286738351, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1786801, Length=572, Percent_Identity=35.8391608391608, Blast_Score=278, Evalue=1e-75,
Organism=Escherichia coli, GI145693145, Length=547, Percent_Identity=25.0457038391225, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1788107, Length=544, Percent_Identity=22.2426470588235, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1786810, Length=531, Percent_Identity=25.4237288135593, Blast_Score=97, Evalue=9e-21,
Organism=Escherichia coli, GI1789201, Length=364, Percent_Identity=26.0989010989011, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI221142682, Length=528, Percent_Identity=23.8636363636364, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17556356, Length=545, Percent_Identity=28.256880733945, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17557194, Length=522, Percent_Identity=24.5210727969349, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17538037, Length=544, Percent_Identity=24.6323529411765, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI32564422, Length=368, Percent_Identity=26.6304347826087, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32564420, Length=368, Percent_Identity=26.6304347826087, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559526, Length=365, Percent_Identity=24.1095890410959, Blast_Score=95, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531443, Length=547, Percent_Identity=22.6691042047532, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=419, Percent_Identity=25.0596658711217, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17558820, Length=508, Percent_Identity=23.8188976377953, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=388, Percent_Identity=22.9381443298969, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71983001, Length=540, Percent_Identity=24.6296296296296, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560308, Length=378, Percent_Identity=24.3386243386243, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982997, Length=540, Percent_Identity=24.6296296296296, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560140, Length=575, Percent_Identity=21.7391304347826, Blast_Score=77, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=684, Percent_Identity=25, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323182, Length=556, Percent_Identity=25, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319264, Length=565, Percent_Identity=23.5398230088496, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319699, Length=376, Percent_Identity=22.0744680851064, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648676, Length=567, Percent_Identity=28.7477954144621, Blast_Score=172, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24582852, Length=380, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21355181, Length=523, Percent_Identity=24.0917782026769, Blast_Score=88, Evalue=4e-17,
Organism=Drosophila melanogaster, GI18859661, Length=389, Percent_Identity=25.9640102827763, Blast_Score=80, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356441, Length=383, Percent_Identity=23.4986945169713, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648253, Length=518, Percent_Identity=21.4285714285714, Blast_Score=74, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648260, Length=429, Percent_Identity=22.1445221445221, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281365686, Length=368, Percent_Identity=23.0978260869565, Blast_Score=71, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 148076; Mature: 148076

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFVTNTKNVIRGKYHPEFLQNEVLADIFAHTAQTLPDKTALIEADKTLSYGELYQQAL
CCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
IMAQHLALKGVKPGHIVGLWLPRGIELLKAQLAICLSGAAWLPFDMDTPADRIAVCLEDA
HHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC
EAVGMITTDEWYEHLAEVPQTKWTNTELQKPLSESVSLAKTTPDQPAYIIYTSGSTGKPK
CCEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHCCCCCCCEEEEEECCCCCCCC
GIVITQKNICHFLRSENSILGIQEQDKVYQGFSVAFDMSFEEIWLSYLVGATLWIAPKSL
EEEEEHHHHHHHHHCCCCEECCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCHHH
VSDPERLCQTLKQEQITVLHAVPTLLALFPEDVPNLRIINLGGEMCPDSLVDRWALPHHQ
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCHHH
MFNTYGPTETTVSASLELLERGKPVTIGKPLPNYGMLVINSERELLEQGETGELCIFGPS
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCHHHHHCCCCCCEEEECCH
VAQGYLGRPDLTADKFIENPWAMSVEEELLYRTGDLAKIDEFGQVHCLGRADDQVKIRGF
HHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCEEEECCCCCCEEEEEE
RVELGEIEAALCDIDGIGTAAVILRPEDGIDQLIAFIAPEIDAKQAIEIKELRHNLSQRL
EEEHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
PPYMVPNRFEIIEEVPRLLSGKIDRKALKARPLTSVVDRSESDQPQNPAEEILFEILNRL
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FPNMPIKLDSDFFDDLGGHSLLAAVLISNLREHAEYSHLTIQNLYQARRVGAIAALMLEQ
CCCCCEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEPTLFDSQIGQDNPRNQTYKWLCGIAQLVTIPVLISINILQWLAPFFTYHYFTGGTRDS
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IPYAIALSLLVYVSVIMSSFVLSITVKRLLMLGIGAGRYPLWGLTYFRWWLADRISNISP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
VYLLSGSTLLNLYLKALGAKIGHDVTISSVHIRMPSLLTIEDGVSIGSQVNLENAKVEHG
EEEECCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECCCCCCCCEECCCCCEECCC
HLVLGSIHLKQDSYVGSYAVLEENTVLEKQAHVNALTSIEYDTVVPEGEIWDGTPAQKIG
EEEEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHC
HIDEQAKLPERPKLSFIRKIAEYGYYGVSALIIACLFFIPIFPSFLLVDWLDVNVFNINP
CCCHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
NNHLQIALYYFILAIPASAMMMMITAVISSGLRKIALPRLEIGTYAVHGSTYYRKWFAAQ
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEECEEEEECCHHHHHHHHHH
ILETSLQTLHGLFATIYAPTWFRMLGAKVGKNTEISTATGVIPEMLTLGEESFIADAVML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHC
GDEEIKGGWMSLKATKIGNRSFVGNSAYIADGTVLPDNVLIGVQSKTPDNREMYDGQTWF
CCHHHCCCEEEEEEEECCCCEECCCCEEEECCEECCCCEEEEEECCCCCCCCCCCCCCCC
GSPALLLPAREAAEKYPDHLTFKPSIKRRLMRGFIEGLRIVLPAALAIGVGYMIVLDVID
CCCEEEECCHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VINNYNIETGLVALTLAGLLYGVGCFLIVALLKWILIGRYQPRSAPMWTMFVWLSEGITS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LYESVAIPNFLNYLRGTPMLPFFLRILGVRIGKDVYMDTADITEFDCVSIGDRAEFNSFS
HHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCCCCCC
GPQTHLFEDRIMKIGQVNVGNDVVVNTRSIILYNANVSNHAVLGPLTLVMKGENIPAKSA
CCCHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCCEEECEEEEEEECCCCCCCCC
WIGSPAVPWVHK
CCCCCCCCCCCC
>Mature Secondary Structure
MNQFVTNTKNVIRGKYHPEFLQNEVLADIFAHTAQTLPDKTALIEADKTLSYGELYQQAL
CCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
IMAQHLALKGVKPGHIVGLWLPRGIELLKAQLAICLSGAAWLPFDMDTPADRIAVCLEDA
HHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC
EAVGMITTDEWYEHLAEVPQTKWTNTELQKPLSESVSLAKTTPDQPAYIIYTSGSTGKPK
CCEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHCCCCCCCEEEEEECCCCCCCC
GIVITQKNICHFLRSENSILGIQEQDKVYQGFSVAFDMSFEEIWLSYLVGATLWIAPKSL
EEEEEHHHHHHHHHCCCCEECCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCHHH
VSDPERLCQTLKQEQITVLHAVPTLLALFPEDVPNLRIINLGGEMCPDSLVDRWALPHHQ
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCHHH
MFNTYGPTETTVSASLELLERGKPVTIGKPLPNYGMLVINSERELLEQGETGELCIFGPS
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCHHHHHCCCCCCEEEECCH
VAQGYLGRPDLTADKFIENPWAMSVEEELLYRTGDLAKIDEFGQVHCLGRADDQVKIRGF
HHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCEEEECCCCCCEEEEEE
RVELGEIEAALCDIDGIGTAAVILRPEDGIDQLIAFIAPEIDAKQAIEIKELRHNLSQRL
EEEHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
PPYMVPNRFEIIEEVPRLLSGKIDRKALKARPLTSVVDRSESDQPQNPAEEILFEILNRL
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FPNMPIKLDSDFFDDLGGHSLLAAVLISNLREHAEYSHLTIQNLYQARRVGAIAALMLEQ
CCCCCEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEPTLFDSQIGQDNPRNQTYKWLCGIAQLVTIPVLISINILQWLAPFFTYHYFTGGTRDS
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IPYAIALSLLVYVSVIMSSFVLSITVKRLLMLGIGAGRYPLWGLTYFRWWLADRISNISP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
VYLLSGSTLLNLYLKALGAKIGHDVTISSVHIRMPSLLTIEDGVSIGSQVNLENAKVEHG
EEEECCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECCCCCCCCEECCCCCEECCC
HLVLGSIHLKQDSYVGSYAVLEENTVLEKQAHVNALTSIEYDTVVPEGEIWDGTPAQKIG
EEEEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHC
HIDEQAKLPERPKLSFIRKIAEYGYYGVSALIIACLFFIPIFPSFLLVDWLDVNVFNINP
CCCHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
NNHLQIALYYFILAIPASAMMMMITAVISSGLRKIALPRLEIGTYAVHGSTYYRKWFAAQ
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEECEEEEECCHHHHHHHHHH
ILETSLQTLHGLFATIYAPTWFRMLGAKVGKNTEISTATGVIPEMLTLGEESFIADAVML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHC
GDEEIKGGWMSLKATKIGNRSFVGNSAYIADGTVLPDNVLIGVQSKTPDNREMYDGQTWF
CCHHHCCCEEEEEEEECCCCEECCCCEEEECCEECCCCEEEEEECCCCCCCCCCCCCCCC
GSPALLLPAREAAEKYPDHLTFKPSIKRRLMRGFIEGLRIVLPAALAIGVGYMIVLDVID
CCCEEEECCHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VINNYNIETGLVALTLAGLLYGVGCFLIVALLKWILIGRYQPRSAPMWTMFVWLSEGITS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LYESVAIPNFLNYLRGTPMLPFFLRILGVRIGKDVYMDTADITEFDCVSIGDRAEFNSFS
HHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCCCCCC
GPQTHLFEDRIMKIGQVNVGNDVVVNTRSIILYNANVSNHAVLGPLTLVMKGENIPAKSA
CCCHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCCEEECEEEEEEECCCCCCCCC
WIGSPAVPWVHK
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]