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The map label for this gene is etfA [H]

Identifier: 213158311

GI number: 213158311

Start: 3133162

End: 3134094

Strand: Reverse

Name: etfA [H]

Synonym: AB57_3038

Alternate gene names: 213158311

Gene position: 3134094-3133162 (Counterclockwise)

Preceding gene: 213158312

Following gene: 213158310

Centisome position: 77.38

GC content: 43.3

Gene sequence:

>933_bases
ATGAGTATTTTAGTTATCGCTGACCACAACAACCAAGTACTTAACGGTGCTACTTTAAACGTTGTTGCTGCAGCTCAAAA
AATCGGTGGTGATATTACTGTATTAGTTGCTGGTTCAGGCGCTCAAGCAGTTGCTGACGCTGCTGCTAAAGTTGCTGGTG
TGAGCAAAGTATTACTTGCTGACAACGCTGCTTATGCAAACCAATTAGCTGAAAACGTAGCTGGCTTAGTTGCTGACTTG
GCTAAAGGTTACAAATACGTTTTAGCTGCTTCTACTACAACTGGTAAGAACATTCTTCCACGTGTTGCTGCGCTTCTTGA
TGTAAGCATGATCACAGACATTATTTCTGTTGAATCGGCTAACACATTCAAGCGTCCAATCTACGCTGGTAACGCAATTG
CAACTGTTCAATCTGACGAAGCAATCATTGTTGGTACTGTTCGTGGTACAGCATTTGATCCAGTTGCTGCGGAAGGTGGT
TCAGCTGCTGTTGAAACAGTTGGCGAAGTAAAAGATGCTGGTGTTTCTAAGTTTGTATCTGAAGAAATCGTTAAACTTGA
TCGTCCAGAATTAACAGCTGCTCGTATTGTTGTATCTGGTGGTCGTGGTGTAGGTTCTGGTGAGAACTACCACAAAGTAC
TTGACCCATTAGCTGACAAGCTTGGTGCAGCACAAGGTGCTTCACGTGCAGCAGTTGATGCAGGCTTCGTACCTAACGAC
TTCCAAGTTGGTCAAACTGGTAAAATCGTTGCACCTGAGCTTTACATTGCTGTAGGTATTTCTGGTGCGATCCAGCACTT
AGCTGGTATGAAAGATTCTAAAGTTATTGTTGCAATCAACAAAGACGAAGAAGCGCCAATCAACAGCGTTGCTGACTACT
GGTTAGTTGGTGATTTGAACGCTGTAGTACCAGAGTTGGTATCTAAGCTTTAA

Upstream 100 bases:

>100_bases
CAGCAGAACGTAAAGCTGGCGTACAAGTGAAATCTGTAGATGAGCTTGTTGAAAAATTGAAAAATGAAGCGAAAGTGATC
TAATACGGAAGGATAAAATC

Downstream 100 bases:

>100_bases
TCTTTATTGATTAAAGTTAAAAACCCCTAGTTTTGAACTAGGGGTTTTTTGTTTTACAGTCTGAAGTTAGAAGTAAAAAT
TAGAAAATTTATGCTTTGGA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSILVIADHNNQVLNGATLNVVAAAQKIGGDITVLVAGSGAQAVADAAAKVAGVSKVLLADNAAYANQLAENVAGLVADL
AKGYKYVLAASTTTGKNILPRVAALLDVSMITDIISVESANTFKRPIYAGNAIATVQSDEAIIVGTVRGTAFDPVAAEGG
SAAVETVGEVKDAGVSKFVSEEIVKLDRPELTAARIVVSGGRGVGSGENYHKVLDPLADKLGAAQGASRAAVDAGFVPND
FQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPINSVADYWLVGDLNAVVPELVSKL

Sequences:

>Translated_310_residues
MSILVIADHNNQVLNGATLNVVAAAQKIGGDITVLVAGSGAQAVADAAAKVAGVSKVLLADNAAYANQLAENVAGLVADL
AKGYKYVLAASTTTGKNILPRVAALLDVSMITDIISVESANTFKRPIYAGNAIATVQSDEAIIVGTVRGTAFDPVAAEGG
SAAVETVGEVKDAGVSKFVSEEIVKLDRPELTAARIVVSGGRGVGSGENYHKVLDPLADKLGAAQGASRAAVDAGFVPND
FQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPINSVADYWLVGDLNAVVPELVSKL
>Mature_309_residues
SILVIADHNNQVLNGATLNVVAAAQKIGGDITVLVAGSGAQAVADAAAKVAGVSKVLLADNAAYANQLAENVAGLVADLA
KGYKYVLAASTTTGKNILPRVAALLDVSMITDIISVESANTFKRPIYAGNAIATVQSDEAIIVGTVRGTAFDPVAAEGGS
AAVETVGEVKDAGVSKFVSEEIVKLDRPELTAARIVVSGGRGVGSGENYHKVLDPLADKLGAAQGASRAAVDAGFVPNDF
QVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPINSVADYWLVGDLNAVVPELVSKL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=56.9131832797428, Blast_Score=336, Evalue=2e-92,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=58.1818181818182, Blast_Score=301, Evalue=6e-82,
Organism=Escherichia coli, GI1787990, Length=301, Percent_Identity=31.2292358803987, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786226, Length=309, Percent_Identity=32.0388349514563, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082157, Length=228, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=54.3130990415335, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6325261, Length=293, Percent_Identity=44.3686006825939, Blast_Score=244, Evalue=1e-65,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=61.0223642172524, Blast_Score=350, Evalue=6e-97,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=61.0223642172524, Blast_Score=350, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31509; Mature: 31378

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVIADHNNQVLNGATLNVVAAAQKIGGDITVLVAGSGAQAVADAAAKVAGVSKVLLA
CEEEEEECCCCEEECCCEEHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEEE
DNAAYANQLAENVAGLVADLAKGYKYVLAASTTTGKNILPRVAALLDVSMITDIISVESA
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NTFKRPIYAGNAIATVQSDEAIIVGTVRGTAFDPVAAEGGSAAVETVGEVKDAGVSKFVS
CCCCCCEECCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EEIVKLDRPELTAARIVVSGGRGVGSGENYHKVLDPLADKLGAAQGASRAAVDAGFVPND
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCC
FQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPINSVADYWLVGDLN
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHEEEECCHH
AVVPELVSKL
HHHHHHHHCC
>Mature Secondary Structure 
SILVIADHNNQVLNGATLNVVAAAQKIGGDITVLVAGSGAQAVADAAAKVAGVSKVLLA
EEEEEECCCCEEECCCEEHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEEE
DNAAYANQLAENVAGLVADLAKGYKYVLAASTTTGKNILPRVAALLDVSMITDIISVESA
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NTFKRPIYAGNAIATVQSDEAIIVGTVRGTAFDPVAAEGGSAAVETVGEVKDAGVSKFVS
CCCCCCEECCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EEIVKLDRPELTAARIVVSGGRGVGSGENYHKVLDPLADKLGAAQGASRAAVDAGFVPND
HHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCC
FQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPINSVADYWLVGDLN
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHEEEECCHH
AVVPELVSKL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]