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The map label for this gene is lolC [H]

Identifier: 213158297

GI number: 213158297

Start: 3115335

End: 3116480

Strand: Reverse

Name: lolC [H]

Synonym: AB57_3022

Alternate gene names: 213158297

Gene position: 3116480-3115335 (Counterclockwise)

Preceding gene: 213158298

Following gene: 213158296

Centisome position: 76.94

GC content: 40.4

Gene sequence:

>1146_bases
ATGGTCGGTTTGACACTTGGTGTCGCTGTACTAATTACGGTACTTTCTGTAATGAACGGTTTCGACCGCGAATTAAAAAA
TCGTGTTTTGGGAATGGTACCGCAAGCGACAGTTTCATCGACGCAAATCCTTACGGATTGGCCTGAACTGGTTAAACGAG
TTGAAAATCATCCCCACGTGACAGGAGTTGCACCTTTTACCCAATTGCAAGGTATGTTAACTGCTCAAGGGCAAGTGGCA
GGTATTATGGTGACGGGTATTGATCCTAAATATGAAAAGAATGTCTCTATCATTCAAAACCATATTGTTGCCGGTAGTCT
CGACTCACTTAAAAAAGGTGAATTCGGTATCGTACTTGGTAAAGACATGGCCGATTCGCTTGGCTTACGTTTAAACGATA
GCGTGACATTGGTTTTACCTGAAGCGACTCCATCTCCAGCTGGTGTTGTACCTCGTTTTAAACGCTTTAAAGTGGTAGGT
ATTTTCAGTGTAGGTGCTGAAGTTGACTCGATGGTTGGATACATTGCTTTATATGATGCTTCAACCTTATTGCGTTTACC
TGATGGCGCTCAAGGCGTTCGTCTAAAATTAGATGATATTTTTGCCGCTCCTCAAGTTGCCGATGACATTGTGAAAAATT
TACCAAGCAATTTCTACGCAACCAACTGGACTTATACACATGGCAACTTATTTAATGCCATCCAAATGGAAAAAACATTA
GTTGGTTTATTGCTTGTACTGATTATTGTTGTTGCTGCATTTAACATTGTTTCGTCTTTAGTTATGGTCGTGACTGACAA
AAAATCAGACATTGCAATTTTACGTACTTTAGGTGCATCGCCATCTATGATTACTAAAATCTTTATGGTGCAAGGTACGG
TTATTGGTGTGATCGGTACAGTTGCGGGTACGGTTTTAGGGGTAATTCTGGCACTTACGATCAGCGATATTATTTCTTGG
TTTAATAATGTTCTCGGACTTAATCTGTTCGATGCCTATTTTGTACATTACTTACCTTCTTACTTAAGATGGCAAGACGT
GACAATTATTGTGATTGTTTCTTTACTCTTAAGTTTCTTGGCAACTATTTATCCGGCGCTTCGTGCAGCCAAAGTTCAAC
CTGCCGAGGCATTGCGTTATGAGTAA

Upstream 100 bases:

>100_bases
TTTAGAAGGTATGTTTAAACCAATCTCACTGTATATAGGGTTGAGATATACTCGCGCTCGACGCAGTAATCATTTTATTT
CTTTTATTGCATTGGTTTCG

Downstream 100 bases:

>100_bases
AGTCGTTTTAGAAGCAAAAGATATTTATAAACATTTTGATGACGGTAAATCTAAGGTTGAAGTCATTAAAGGTCTCTCTT
TACAAGTGGAAGCAGGGCAG

Product: lipoprotein-releasing system transmembrane protein LolE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MVGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATVSSTQILTDWPELVKRVENHPHVTGVAPFTQLQGMLTAQGQVA
GIMVTGIDPKYEKNVSIIQNHIVAGSLDSLKKGEFGIVLGKDMADSLGLRLNDSVTLVLPEATPSPAGVVPRFKRFKVVG
IFSVGAEVDSMVGYIALYDASTLLRLPDGAQGVRLKLDDIFAAPQVADDIVKNLPSNFYATNWTYTHGNLFNAIQMEKTL
VGLLLVLIIVVAAFNIVSSLVMVVTDKKSDIAILRTLGASPSMITKIFMVQGTVIGVIGTVAGTVLGVILALTISDIISW
FNNVLGLNLFDAYFVHYLPSYLRWQDVTIIVIVSLLLSFLATIYPALRAAKVQPAEALRYE

Sequences:

>Translated_381_residues
MVGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATVSSTQILTDWPELVKRVENHPHVTGVAPFTQLQGMLTAQGQVA
GIMVTGIDPKYEKNVSIIQNHIVAGSLDSLKKGEFGIVLGKDMADSLGLRLNDSVTLVLPEATPSPAGVVPRFKRFKVVG
IFSVGAEVDSMVGYIALYDASTLLRLPDGAQGVRLKLDDIFAAPQVADDIVKNLPSNFYATNWTYTHGNLFNAIQMEKTL
VGLLLVLIIVVAAFNIVSSLVMVVTDKKSDIAILRTLGASPSMITKIFMVQGTVIGVIGTVAGTVLGVILALTISDIISW
FNNVLGLNLFDAYFVHYLPSYLRWQDVTIIVIVSLLLSFLATIYPALRAAKVQPAEALRYE
>Mature_381_residues
MVGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATVSSTQILTDWPELVKRVENHPHVTGVAPFTQLQGMLTAQGQVA
GIMVTGIDPKYEKNVSIIQNHIVAGSLDSLKKGEFGIVLGKDMADSLGLRLNDSVTLVLPEATPSPAGVVPRFKRFKVVG
IFSVGAEVDSMVGYIALYDASTLLRLPDGAQGVRLKLDDIFAAPQVADDIVKNLPSNFYATNWTYTHGNLFNAIQMEKTL
VGLLLVLIIVVAAFNIVSSLVMVVTDKKSDIAILRTLGASPSMITKIFMVQGTVIGVIGTVAGTVLGVILALTISDIISW
FNNVLGLNLFDAYFVHYLPSYLRWQDVTIIVIVSLLLSFLATIYPALRAAKVQPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=380, Percent_Identity=36.8421052631579, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787360, Length=382, Percent_Identity=37.17277486911, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41138; Mature: 41138

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATVSSTQILTDWPELVKRVENHPHV
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCE
TGVAPFTQLQGMLTAQGQVAGIMVTGIDPKYEKNVSIIQNHIVAGSLDSLKKGEFGIVLG
ECCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEEEC
KDMADSLGLRLNDSVTLVLPEATPSPAGVVPRFKRFKVVGIFSVGAEVDSMVGYIALYDA
CCHHHHCCCEECCCEEEEEECCCCCCCCCCCCCHHEEEEEEEECCCHHHHHHHHHHEECC
STLLRLPDGAQGVRLKLDDIFAAPQVADDIVKNLPSNFYATNWTYTHGNLFNAIQMEKTL
CCEEECCCCCCCCEEEHHHHHCCHHHHHHHHHHCCCCCEECCEEEECCCHHHHHHHHHHH
VGLLLVLIIVVAAFNIVSSLVMVVTDKKSDIAILRTLGASPSMITKIFMVQGTVIGVIGT
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VAGTVLGVILALTISDIISWFNNVLGLNLFDAYFVHYLPSYLRWQDVTIIVIVSLLLSFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ATIYPALRAAKVQPAEALRYE
HHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MVGLTLGVAVLITVLSVMNGFDRELKNRVLGMVPQATVSSTQILTDWPELVKRVENHPHV
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCE
TGVAPFTQLQGMLTAQGQVAGIMVTGIDPKYEKNVSIIQNHIVAGSLDSLKKGEFGIVLG
ECCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEEEC
KDMADSLGLRLNDSVTLVLPEATPSPAGVVPRFKRFKVVGIFSVGAEVDSMVGYIALYDA
CCHHHHCCCEECCCEEEEEECCCCCCCCCCCCCHHEEEEEEEECCCHHHHHHHHHHEECC
STLLRLPDGAQGVRLKLDDIFAAPQVADDIVKNLPSNFYATNWTYTHGNLFNAIQMEKTL
CCEEECCCCCCCCEEEHHHHHCCHHHHHHHHHHCCCCCEECCEEEECCCHHHHHHHHHHH
VGLLLVLIIVVAAFNIVSSLVMVVTDKKSDIAILRTLGASPSMITKIFMVQGTVIGVIGT
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VAGTVLGVILALTISDIISWFNNVLGLNLFDAYFVHYLPSYLRWQDVTIIVIVSLLLSFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ATIYPALRAAKVQPAEALRYE
HHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]