Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 213158282

GI number: 213158282

Start: 3097428

End: 3098399

Strand: Direct

Name: fbp [H]

Synonym: AB57_3005

Alternate gene names: 213158282

Gene position: 3097428-3098399 (Clockwise)

Preceding gene: 213158280

Following gene: 213158283

Centisome position: 76.47

GC content: 40.12

Gene sequence:

>972_bases
ATGTCCAACCTCACATTGTCCCAATTTTTACAACAAGAAAAAGGGAATCTTACACCTGAGTTGGCTCAAGTCATCGACAC
AATTGCTGCGACTTGTAAAACCATTGATCAAGCCTTACAAAAAGGTGCCTTGGCTGGAATTTTGGGTAGCGCAGGTAACG
AAAATGTTCAAGGTGAAACACAGAAAAAACTTGATGTGATTTCTAATGACTATTTAATCGATGCTTTAAAAGTCCATCCT
CACGTGGGTGGTCTTGCATCTGAAGAACTTGATGATTTTACACCAGCACAAGAAAACGGCGAATACTTGGTTCTATTTGA
TCCATTAGATGGTTCAAGCAACATTGATATCAACATGTGTGTCGGAACAATCTTCTCGATTCTTCCTGCCAAAAATGCGA
TTACACAAGCACAAGATTTCATGCAGGCAGGCACTCAACAAGTTGCTGCTGGCTATGTGTTATATGGCCCATCAACTATG
ATGGCTTTAACAGTTGGAAACGGTGTAGCTTTCTTTACGTTAGATCCAGTAACTCAAACATTCTTACTTACTACAGAGAA
TGTTCAAGTATCAGCAGATACTCAAGAATTTGCTATTAATGCATCTAACCAACGCCATTGGGAACAACCAGTAAAACAAT
ATATTGAAGAGTTACTTGCAGGTAAAACATCTGTACGTGAAAAAGACTTCAATATGCGTTGGGTCGCATGTATGGTGGGT
GATGTTCACCGTATTTTATGCCGTGGCGGTATTTTCCTTTATCCATATGACTTGAAAGACCCGAAAAAAGCTGGTCGTTT
ACGTTTAATGTATGAAGCTAACCCAATGAGTATGCTCATTGAACAAGCAGGCGGCGCATCAACTACTGGCCGTGTACGCA
TTCTAGAGATTGAACCAACAGAACTTCATCAACGTGTTCCTGTGATTATCGGTTCTAAGAATGAAGTTGAACGCGTAACA
AGCTATCATTAA

Upstream 100 bases:

>100_bases
AAATAAAGTAAGATAATTTTTATTTTTCGGCATTCTCATCTAGAATATGCCACGTATTTATCTGACTCATTTTGATGCTT
GCGCACAGGAGCGTTTTTTT

Downstream 100 bases:

>100_bases
TAATTTAAATTACACAGGGCGTCATAGTATGATGACGCCCTTTTGGATATTCCCTTATGGCGGTTATTTTTTTAGAATCA
AAAGACAATGCAAAAATTAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSNLTLSQFLQQEKGNLTPELAQVIDTIAATCKTIDQALQKGALAGILGSAGNENVQGETQKKLDVISNDYLIDALKVHP
HVGGLASEELDDFTPAQENGEYLVLFDPLDGSSNIDINMCVGTIFSILPAKNAITQAQDFMQAGTQQVAAGYVLYGPSTM
MALTVGNGVAFFTLDPVTQTFLLTTENVQVSADTQEFAINASNQRHWEQPVKQYIEELLAGKTSVREKDFNMRWVACMVG
DVHRILCRGGIFLYPYDLKDPKKAGRLRLMYEANPMSMLIEQAGGASTTGRVRILEIEPTELHQRVPVIIGSKNEVERVT
SYH

Sequences:

>Translated_323_residues
MSNLTLSQFLQQEKGNLTPELAQVIDTIAATCKTIDQALQKGALAGILGSAGNENVQGETQKKLDVISNDYLIDALKVHP
HVGGLASEELDDFTPAQENGEYLVLFDPLDGSSNIDINMCVGTIFSILPAKNAITQAQDFMQAGTQQVAAGYVLYGPSTM
MALTVGNGVAFFTLDPVTQTFLLTTENVQVSADTQEFAINASNQRHWEQPVKQYIEELLAGKTSVREKDFNMRWVACMVG
DVHRILCRGGIFLYPYDLKDPKKAGRLRLMYEANPMSMLIEQAGGASTTGRVRILEIEPTELHQRVPVIIGSKNEVERVT
SYH
>Mature_322_residues
SNLTLSQFLQQEKGNLTPELAQVIDTIAATCKTIDQALQKGALAGILGSAGNENVQGETQKKLDVISNDYLIDALKVHPH
VGGLASEELDDFTPAQENGEYLVLFDPLDGSSNIDINMCVGTIFSILPAKNAITQAQDFMQAGTQQVAAGYVLYGPSTMM
ALTVGNGVAFFTLDPVTQTFLLTTENVQVSADTQEFAINASNQRHWEQPVKQYIEELLAGKTSVREKDFNMRWVACMVGD
VHRILCRGGIFLYPYDLKDPKKAGRLRLMYEANPMSMLIEQAGGASTTGRVRILEIEPTELHQRVPVIIGSKNEVERVTS
YH

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=317, Percent_Identity=40.6940063091483, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI16579888, Length=317, Percent_Identity=40.6940063091483, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI22907028, Length=324, Percent_Identity=40.1234567901235, Blast_Score=227, Evalue=1e-59,
Organism=Escherichia coli, GI1790679, Length=327, Percent_Identity=42.5076452599388, Blast_Score=249, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17508131, Length=329, Percent_Identity=42.5531914893617, Blast_Score=252, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6323409, Length=327, Percent_Identity=35.7798165137615, Blast_Score=215, Evalue=9e-57,
Organism=Drosophila melanogaster, GI45550998, Length=325, Percent_Identity=40.6153846153846, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI19921562, Length=325, Percent_Identity=40.6153846153846, Blast_Score=233, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35441; Mature: 35310

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLTLSQFLQQEKGNLTPELAQVIDTIAATCKTIDQALQKGALAGILGSAGNENVQGET
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCH
QKKLDVISNDYLIDALKVHPHVGGLASEELDDFTPAQENGEYLVLFDPLDGSSNIDINMC
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEHHH
VGTIFSILPAKNAITQAQDFMQAGTQQVAAGYVLYGPSTMMALTVGNGVAFFTLDPVTQT
HHHHHHHHCCCHHHHHHHHHHHHCHHHHHCCEEEECCCEEEEEEECCCEEEEEECCCCEE
FLLTTENVQVSADTQEFAINASNQRHWEQPVKQYIEELLAGKTSVREKDFNMRWVACMVG
EEEEECCEEEECCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
DVHRILCRGGIFLYPYDLKDPKKAGRLRLMYEANPMSMLIEQAGGASTTGRVRILEIEPT
HHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCEEEEEECHH
ELHQRVPVIIGSKNEVERVTSYH
HHHCCCCEEECCCHHHHHHHCCC
>Mature Secondary Structure 
SNLTLSQFLQQEKGNLTPELAQVIDTIAATCKTIDQALQKGALAGILGSAGNENVQGET
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCH
QKKLDVISNDYLIDALKVHPHVGGLASEELDDFTPAQENGEYLVLFDPLDGSSNIDINMC
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEHHH
VGTIFSILPAKNAITQAQDFMQAGTQQVAAGYVLYGPSTMMALTVGNGVAFFTLDPVTQT
HHHHHHHHCCCHHHHHHHHHHHHCHHHHHCCEEEECCCEEEEEEECCCEEEEEECCCCEE
FLLTTENVQVSADTQEFAINASNQRHWEQPVKQYIEELLAGKTSVREKDFNMRWVACMVG
EEEEECCEEEECCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
DVHRILCRGGIFLYPYDLKDPKKAGRLRLMYEANPMSMLIEQAGGASTTGRVRILEIEPT
HHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCEEEEEECHH
ELHQRVPVIIGSKNEVERVTSYH
HHHCCCCEEECCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA