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The map label for this gene is pabC [H]

Identifier: 213158252

GI number: 213158252

Start: 3067192

End: 3068004

Strand: Reverse

Name: pabC [H]

Synonym: AB57_2971

Alternate gene names: 213158252

Gene position: 3068004-3067192 (Counterclockwise)

Preceding gene: 213158259

Following gene: 213158251

Centisome position: 75.74

GC content: 38.62

Gene sequence:

>813_bases
ATGTGGTGTTTTAAAAATGGACAACCTGTAGAGACCATTCCTTTATTGGACCGGGCATTTCATTATGGGGATGGCTGCTT
TACCACAATTCGTGTTTTTCAAAATAAGATTGAGCTTAAAGCACGGCACTGGGAACGTCTAAAACTTGCTTGCCAAAAAT
TATCTTTGGTTGCAGATTTTGAGTTAATCGAACAAAGTTTGCAGCATCTACAAAATCAGAATCTCGTGCTCAACGGGACT
TTAAAAATTGTGATTAGCCGTGGTGAAGGTGATCGTGGCTATAGTTTGCCAAAGCATGCGGCAGATATTTATATCTGGTT
TTATCCAAAAGCATTGGAGCAGTTCCAACCAGATTTTATTGAGTGTGGAGTTTTAAATCAGGCTTTAGGTTTAACCATGC
CGAGTTTAGTTGGGCTTAAATCCTTAAACCGTCTTGAGCAGGTATTGCTAAAAAAAGAAGCAGATCAACAAGGCTGGGTT
GAAGCTTTAGTAACTGATGTACAAGGTTATATTGTTGAAGGGGTAAGCAGTAATTGTTTTATTCTTTTAAATGATAGATG
GATTACTCCGGAACTTCGCTATAATGGCGTCCACGGTGTGATGCGTGCAGAAATTTTGGCGCGTATGCAGCACTACGGAA
TTGCCTGTGAAGTCAGAATAATTGAGCTAGATGAAGTACCACAAATACAGAGTCTATTCTTTTGTAATGCTTTACATCCA
ATGCGAGTAGTTACTCAAATCAGTGAACAAATTCTAGAGTCACAGGCGTGCCTAAATTTATTTCATACTCTTAACTTGAA
TCAGATTCATTAA

Upstream 100 bases:

>100_bases
GTTTCTCTTAAATCGGTATAATTTTTTAAAATCAGTCATTTATTAATTAAATGAAAGGTGTTGTATTGTTGGGTGGTTTT
AAATAAAGGACGGATTAAGC

Downstream 100 bases:

>100_bases
TATGCCGAAGCCACCTGTGAATGCGAAAGCAAAAAATGCTAAAAAAAAGGGCAAGAAAACAGCATCTAATTTTCCAAAAA
AGTTAGTGCTGATTGGCTGT

Product: aminodeoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MWCFKNGQPVETIPLLDRAFHYGDGCFTTIRVFQNKIELKARHWERLKLACQKLSLVADFELIEQSLQHLQNQNLVLNGT
LKIVISRGEGDRGYSLPKHAADIYIWFYPKALEQFQPDFIECGVLNQALGLTMPSLVGLKSLNRLEQVLLKKEADQQGWV
EALVTDVQGYIVEGVSSNCFILLNDRWITPELRYNGVHGVMRAEILARMQHYGIACEVRIIELDEVPQIQSLFFCNALHP
MRVVTQISEQILESQACLNLFHTLNLNQIH

Sequences:

>Translated_270_residues
MWCFKNGQPVETIPLLDRAFHYGDGCFTTIRVFQNKIELKARHWERLKLACQKLSLVADFELIEQSLQHLQNQNLVLNGT
LKIVISRGEGDRGYSLPKHAADIYIWFYPKALEQFQPDFIECGVLNQALGLTMPSLVGLKSLNRLEQVLLKKEADQQGWV
EALVTDVQGYIVEGVSSNCFILLNDRWITPELRYNGVHGVMRAEILARMQHYGIACEVRIIELDEVPQIQSLFFCNALHP
MRVVTQISEQILESQACLNLFHTLNLNQIH
>Mature_270_residues
MWCFKNGQPVETIPLLDRAFHYGDGCFTTIRVFQNKIELKARHWERLKLACQKLSLVADFELIEQSLQHLQNQNLVLNGT
LKIVISRGEGDRGYSLPKHAADIYIWFYPKALEQFQPDFIECGVLNQALGLTMPSLVGLKSLNRLEQVLLKKEADQQGWV
EALVTDVQGYIVEGVSSNCFILLNDRWITPELRYNGVHGVMRAEILARMQHYGIACEVRIIELDEVPQIQSLFFCNALHP
MRVVTQISEQILESQACLNLFHTLNLNQIH

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=246, Percent_Identity=36.1788617886179, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30960; Mature: 30960

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWCFKNGQPVETIPLLDRAFHYGDGCFTTIRVFQNKIELKARHWERLKLACQKLSLVADF
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELIEQSLQHLQNQNLVLNGTLKIVISRGEGDRGYSLPKHAADIYIWFYPKALEQFQPDFI
HHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHHHHCCCHH
ECGVLNQALGLTMPSLVGLKSLNRLEQVLLKKEADQQGWVEALVTDVQGYIVEGVSSNCF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCEE
ILLNDRWITPELRYNGVHGVMRAEILARMQHYGIACEVRIIELDEVPQIQSLFFCNALHP
EEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCH
MRVVTQISEQILESQACLNLFHTLNLNQIH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MWCFKNGQPVETIPLLDRAFHYGDGCFTTIRVFQNKIELKARHWERLKLACQKLSLVADF
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELIEQSLQHLQNQNLVLNGTLKIVISRGEGDRGYSLPKHAADIYIWFYPKALEQFQPDFI
HHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHHHHCCCHH
ECGVLNQALGLTMPSLVGLKSLNRLEQVLLKKEADQQGWVEALVTDVQGYIVEGVSSNCF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCEE
ILLNDRWITPELRYNGVHGVMRAEILARMQHYGIACEVRIIELDEVPQIQSLFFCNALHP
EEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCH
MRVVTQISEQILESQACLNLFHTLNLNQIH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]