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The map label for this gene is lepB [H]

Identifier: 213158244

GI number: 213158244

Start: 3058189

End: 3059016

Strand: Reverse

Name: lepB [H]

Synonym: AB57_2963

Alternate gene names: 213158244

Gene position: 3059016-3058189 (Counterclockwise)

Preceding gene: 213158245

Following gene: 213158243

Centisome position: 75.52

GC content: 37.32

Gene sequence:

>828_bases
GTGGATTTTGATTTTAATTTAATTCTTGTTCCTGTTACGCTGATTTTATTTGCAGTGTGGTTGCTAGATAAGCTTGTTTT
TAAACAGCGTGCAAATAAAGGGCGAGAGAACGAAAATTTTGTTATTACATGGGCCTATGACTTTTGGCCGGTTTTAGCTG
TTGTGCTTGTACTTCGCTCATTTCTTTATGAACCATTTAATATTCCATCAGACTCTATGGTTCCGACCTTAGAGACTGGC
GATTTTATTTTAGTTAATAAATTTGACTATGGTGTCCGTTTACCTATCGTCAATAAAAAAGTGATTGATATCGGTGAACC
GAAACGTGGTGATGTCATCGTTTTTCGTTATCCACCACAACCTACTATTAGTTATATTAAACGTGTAATTGGCTTACCTG
GTGACCATATTGTTTATGATCATGGACAATTGATTATTAATGGTCAAAAAATTCCTAAAGTACCAACACAGTTTAGTCGC
GAAAAAGATGCTTTAGATACACCAACTTCTATTTATCATAAAGAAACAATTGGTGATCATACCTTTACGATGCGTGAGCT
TGAAGGCGTAAATGTTGCGCGTCAGGCACCATTTATCAACTATGTTGATAATGGTAAATATGCAAACCAAGACGGTTTAT
ATTGGGAAGTAACAGTTCCGAAAGGACATTACTTTGCAATGGGGGATAACCGTGATCAAAGTGCTGACAGTCGTTTCTGG
GGCTTCGTACCTGAAGAAAATTTAACAGGCCGAGCTTTCTATGTCTGGATGCATAAAGAACCTGGTTTCCACCTGCCAAG
CTTTAACCGAAATGGGAAAATAGATTAA

Upstream 100 bases:

>100_bases
TTCTTAGCTGTTTTGAAAGTAGAAAGATAAGAGAAAAGGCTGGGATGAACTTATCTTCTCCCAGCCGCAAGGCAAGCAGC
TAAGCTGCGAGTGAGGTCCT

Downstream 100 bases:

>100_bases
AAACAACCATTAGGAAAACAAAAATGCGTAAGGCACAACAGGGTACTTCGTATTTAGCAATTTTATTTGGGGTGGTCATA
TTTGCAATTGCGGTGAAAGC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MDFDFNLILVPVTLILFAVWLLDKLVFKQRANKGRENENFVITWAYDFWPVLAVVLVLRSFLYEPFNIPSDSMVPTLETG
DFILVNKFDYGVRLPIVNKKVIDIGEPKRGDVIVFRYPPQPTISYIKRVIGLPGDHIVYDHGQLIINGQKIPKVPTQFSR
EKDALDTPTSIYHKETIGDHTFTMRELEGVNVARQAPFINYVDNGKYANQDGLYWEVTVPKGHYFAMGDNRDQSADSRFW
GFVPEENLTGRAFYVWMHKEPGFHLPSFNRNGKID

Sequences:

>Translated_275_residues
MDFDFNLILVPVTLILFAVWLLDKLVFKQRANKGRENENFVITWAYDFWPVLAVVLVLRSFLYEPFNIPSDSMVPTLETG
DFILVNKFDYGVRLPIVNKKVIDIGEPKRGDVIVFRYPPQPTISYIKRVIGLPGDHIVYDHGQLIINGQKIPKVPTQFSR
EKDALDTPTSIYHKETIGDHTFTMRELEGVNVARQAPFINYVDNGKYANQDGLYWEVTVPKGHYFAMGDNRDQSADSRFW
GFVPEENLTGRAFYVWMHKEPGFHLPSFNRNGKID
>Mature_275_residues
MDFDFNLILVPVTLILFAVWLLDKLVFKQRANKGRENENFVITWAYDFWPVLAVVLVLRSFLYEPFNIPSDSMVPTLETG
DFILVNKFDYGVRLPIVNKKVIDIGEPKRGDVIVFRYPPQPTISYIKRVIGLPGDHIVYDHGQLIINGQKIPKVPTQFSR
EKDALDTPTSIYHKETIGDHTFTMRELEGVNVARQAPFINYVDNGKYANQDGLYWEVTVPKGHYFAMGDNRDQSADSRFW
GFVPEENLTGRAFYVWMHKEPGFHLPSFNRNGKID

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=304, Percent_Identity=39.1447368421053, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 31748; Mature: 31748

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDFNLILVPVTLILFAVWLLDKLVFKQRANKGRENENFVITWAYDFWPVLAVVLVLRS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHH
FLYEPFNIPSDSMVPTLETGDFILVNKFDYGVRLPIVNKKVIDIGEPKRGDVIVFRYPPQ
HHCCCCCCCCCCCCCEECCCCEEEEEECCCCEEEEECCCEEEECCCCCCCCEEEEEECCC
PTISYIKRVIGLPGDHIVYDHGQLIINGQKIPKVPTQFSREKDALDTPTSIYHKETIGDH
CHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHHCCCC
TFTMRELEGVNVARQAPFINYVDNGKYANQDGLYWEVTVPKGHYFAMGDNRDQSADSRFW
EEEEHHHCCCCHHHCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCEE
GFVPEENLTGRAFYVWMHKEPGFHLPSFNRNGKID
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDFDFNLILVPVTLILFAVWLLDKLVFKQRANKGRENENFVITWAYDFWPVLAVVLVLRS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHH
FLYEPFNIPSDSMVPTLETGDFILVNKFDYGVRLPIVNKKVIDIGEPKRGDVIVFRYPPQ
HHCCCCCCCCCCCCCEECCCCEEEEEECCCCEEEEECCCEEEECCCCCCCCEEEEEECCC
PTISYIKRVIGLPGDHIVYDHGQLIINGQKIPKVPTQFSREKDALDTPTSIYHKETIGDH
CHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHHCCCC
TFTMRELEGVNVARQAPFINYVDNGKYANQDGLYWEVTVPKGHYFAMGDNRDQSADSRFW
EEEEHHHCCCCHHHCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCEE
GFVPEENLTGRAFYVWMHKEPGFHLPSFNRNGKID
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1546969 [H]