Click here to switch to the map view.

The map label for this gene is pdxJ [H]

Identifier: 213158238

GI number: 213158238

Start: 3054412

End: 3055137

Strand: Reverse

Name: pdxJ [H]

Synonym: AB57_2957

Alternate gene names: 213158238

Gene position: 3055137-3054412 (Counterclockwise)

Preceding gene: 213158239

Following gene: 213158237

Centisome position: 75.43

GC content: 42.56

Gene sequence:

>726_bases
ATGGCTGCATTGCTTGGTGTAAACATAGACCATGTTGCTACTTTAAGACAGGCGCGCGGTAATGCTTACCCAGACCCTGT
AGAAGCTGCTCTTATTTGTGAACAAGCGGGTGCAGAGGGGATTACTTTGCATTTGCGTGAAGATCGCAGACATATTCAAG
ATGATGACGTGCGCCGTATGCGTCCATTATTGAAAACACGTATGAATCTTGAAATGGCCGTAACTGATGAAATGGTTGAG
TTTGCGAAAGAAATTCAACCGCAACATGTGTGTTTTGTACCAGAACGACGCCAAGAAGTTACAACAGAAGGCGGTTTAGA
TGTAGTGGGTAACTTTGAAAAAGTTAAAGCTGCAACTCAAGCCTTAGCTGCCATTGGTTGTGATGTTTCACTCTTTATTG
ATGCTGATTTTGCTCAAATTGATGCAGCAATTGCTTGTGGAGCGCCTACTATTGAATTACATACTGGGGCGTATGCAGAT
GCAACAACAGAGCAAGAGCAACAAGAAGAACTTGCTCGCATTGTAAAAGGTGTGGAATACGCAGCTTCAAAAGGTTTGGT
TGTAAATGCTGGTCACGGTTTGAATCTGAAAAATATTGCTCCAATTGCGGCAATTCCACAAATTCATGAGTTAAATATTG
GTCACTCAATTATTGCGGAAAGTGTTTTTGTTGGACTGGTACAGGCGGTGAAAGACATGAAAACAGCGATTCAGGCAGCA
GGATAA

Upstream 100 bases:

>100_bases
TACCGTCAAATGATTACATCGCTTTTAGGTGACCGTCCCCTAAAAAGTCGACAATTGTGGATTCAAAATACTCAAACTCA
ATCGTAATTAGGATTTTTTT

Downstream 100 bases:

>100_bases
GTAGTAATGTCGAGTATCAATTACGATGAATTAATGCAGCCTGTATTAGCATTTTTAGGGTGCCAAACCCCAAAAGAATG
GTTGGATGAGGCCGTTAATA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MAALLGVNIDHVATLRQARGNAYPDPVEAALICEQAGAEGITLHLREDRRHIQDDDVRRMRPLLKTRMNLEMAVTDEMVE
FAKEIQPQHVCFVPERRQEVTTEGGLDVVGNFEKVKAATQALAAIGCDVSLFIDADFAQIDAAIACGAPTIELHTGAYAD
ATTEQEQQEELARIVKGVEYAASKGLVVNAGHGLNLKNIAPIAAIPQIHELNIGHSIIAESVFVGLVQAVKDMKTAIQAA
G

Sequences:

>Translated_241_residues
MAALLGVNIDHVATLRQARGNAYPDPVEAALICEQAGAEGITLHLREDRRHIQDDDVRRMRPLLKTRMNLEMAVTDEMVE
FAKEIQPQHVCFVPERRQEVTTEGGLDVVGNFEKVKAATQALAAIGCDVSLFIDADFAQIDAAIACGAPTIELHTGAYAD
ATTEQEQQEELARIVKGVEYAASKGLVVNAGHGLNLKNIAPIAAIPQIHELNIGHSIIAESVFVGLVQAVKDMKTAIQAA
G
>Mature_240_residues
AALLGVNIDHVATLRQARGNAYPDPVEAALICEQAGAEGITLHLREDRRHIQDDDVRRMRPLLKTRMNLEMAVTDEMVEF
AKEIQPQHVCFVPERRQEVTTEGGLDVVGNFEKVKAATQALAAIGCDVSLFIDADFAQIDAAIACGAPTIELHTGAYADA
TTEQEQQEELARIVKGVEYAASKGLVVNAGHGLNLKNIAPIAAIPQIHELNIGHSIIAESVFVGLVQAVKDMKTAIQAAG

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=231, Percent_Identity=65.3679653679654, Blast_Score=301, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 25936; Mature: 25805

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALLGVNIDHVATLRQARGNAYPDPVEAALICEQAGAEGITLHLREDRRHIQDDDVRRM
CCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECHHCCCCCCHHHHH
RPLLKTRMNLEMAVTDEMVEFAKEIQPQHVCFVPERRQEVTTEGGLDVVGNFEKVKAATQ
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHH
ALAAIGCDVSLFIDADFAQIDAAIACGAPTIELHTGAYADATTEQEQQEELARIVKGVEY
HHHHHCCCEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
AASKGLVVNAGHGLNLKNIAPIAAIPQIHELNIGHSIIAESVFVGLVQAVKDMKTAIQAA
HHCCCEEEECCCCCCCCCCCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
G
C
>Mature Secondary Structure 
AALLGVNIDHVATLRQARGNAYPDPVEAALICEQAGAEGITLHLREDRRHIQDDDVRRM
CEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECHHCCCCCCHHHHH
RPLLKTRMNLEMAVTDEMVEFAKEIQPQHVCFVPERRQEVTTEGGLDVVGNFEKVKAATQ
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHH
ALAAIGCDVSLFIDADFAQIDAAIACGAPTIELHTGAYADATTEQEQQEELARIVKGVEY
HHHHHCCCEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
AASKGLVVNAGHGLNLKNIAPIAAIPQIHELNIGHSIIAESVFVGLVQAVKDMKTAIQAA
HHCCCEEEECCCCCCCCCCCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA