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The map label for this gene is ddc [H]

Identifier: 213158166

GI number: 213158166

Start: 2971946

End: 2973478

Strand: Reverse

Name: ddc [H]

Synonym: AB57_2880

Alternate gene names: 213158166

Gene position: 2973478-2971946 (Counterclockwise)

Preceding gene: 213158167

Following gene: 213158165

Centisome position: 73.41

GC content: 41.75

Gene sequence:

>1533_bases
ATGGTGGATTTTGCAGAACATCGTAAAGCGTTACTCTGCAATGATGCACAATCCATTGCTGACTATGAGTCAGCAATGGG
CGAAGCGGTAAAAGCCGTTTCAGCATGGTTGCAAAATGAAAAAATGTACACAGGCGGTAGCATTAAAGAGTTGCGTTCAG
CAATTTCTTTCCAACCTTCAAAAGAAGGTATGGGTGTACAACAATCTCTTCAACGTATGATTGAGCTTTTCTTGAATAAA
AGCTTGAAAGTACACCATCCACATTCATTAGCACATTTACACTGCCCAACCATGGTGATGAGCCAGATCGCGGAAGTGTT
AATCAATGCAACTAACCAGTCTATGGACTCATGGGATCAAAGCCCGGCAGGTTCATTAATGGAAGTGCAGCTTATTGATT
GGTTGCGTCAAAAAGTAGGTTACGGTTCTGGTCAGGCAGGTGTTTTCACTTCTGGCGGTACTCAATCTAACTTGATGGGT
GTATTACTTGCTCGTGACTGGTGTATCTCGAAAAACTGGAAAGACGAAAATGGTAACCCATGGTCTGTACAGCGTGATGG
TATTCCAGCTGAAGCAATGAAAAACGTCAAAGTCATTTGTTCTGAAAATGCGCATTTCTCTGTGCAAAAGAACATGGCAA
TGATGGGCATGGGCTTCCAGTCAGTTGTGACTGTACCTGTGAATGAAAATGCACAGATGGATGTTGATGCTCTTGAAAAA
ACAATGGCGCATCTTCAAGCTGAAGGTAAAGTTGTTGCTTGTGTCGTTGCGACAGCGGGTACAACTGATGCTGGTGCAAT
TGATCCATTGAAAAAAATCCGTGAAATTACTAATAAGTATGGTTCATGGATGCATATCGATGCTGCGTGGGGCGGTGCAC
TGATCTTGTCAAATGACTATCGTGCAATGCTTGATGGTATTGAGCTGTCTGATTCGATCACTCTCGACTTCCATAAGCAT
TATTTCCAAAGCATCAGCTGTGGTGCGTTCTTGTTAAAAGATGAAGCGAACTATCGTTTCATGCATTATGAAGCTGAGTA
CTTGAACTCTGCTTATGATGAAGAGCATGGCGTACCTAACCTTGTGTCTAAATCATTACAAACGACTCGTCGTTTTGATG
CTTTAAAATTGTGGATGACCATTGAATCACTCGGCGAAGAGCTATATGGTTCAATGATTGATCATGGTGTAAAACTGACT
CGTGAAGTTGCAGATTACATCAAGGCAACTGAAGGTTTAGAGCTTTTAGTTGAACCACAATTTGCTTCGGTATTGTTCCG
TGTTGTTCCAGAAGGTTACCCAGTTGAGTTTATCGATAGCTTGAACCAAAACGTAGCAGATGAATTGTTTGCACGTGGTG
AAGCAAATATTGGTGTAACAAAAGTTGGTAATGTACAGTCATTGAAGATGACAACATTAAGCCCTGTAGTAACTGTCGAC
AACGTTAAGAACCTTTTAGCTCAAGTATTGGCTGAAGCTGAACGTATTAAAGATGCGATTGCTTCTGGTAACTACGTACC
ACCAATCGACTAA

Upstream 100 bases:

>100_bases
TTTGCCCACTCATCATTACTCAAGAAGAGTGTGTAGAAGTAATTGCTCGCTTTAAGAAAGCAGTTGCAGAAGCATTGGTT
GCAGTGCGAGGCGCGTAAGT

Downstream 100 bases:

>100_bases
TTGAGTTGATACCCCAAAAAGCTCGGTTTATTGCCGGGCTTTTTTATTACATATTATTTTTATTAAAAGTGTGTATCAGA
AGAAGGGTATATGCACAAAA

Product: diaminobutyrate decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MVDFAEHRKALLCNDAQSIADYESAMGEAVKAVSAWLQNEKMYTGGSIKELRSAISFQPSKEGMGVQQSLQRMIELFLNK
SLKVHHPHSLAHLHCPTMVMSQIAEVLINATNQSMDSWDQSPAGSLMEVQLIDWLRQKVGYGSGQAGVFTSGGTQSNLMG
VLLARDWCISKNWKDENGNPWSVQRDGIPAEAMKNVKVICSENAHFSVQKNMAMMGMGFQSVVTVPVNENAQMDVDALEK
TMAHLQAEGKVVACVVATAGTTDAGAIDPLKKIREITNKYGSWMHIDAAWGGALILSNDYRAMLDGIELSDSITLDFHKH
YFQSISCGAFLLKDEANYRFMHYEAEYLNSAYDEEHGVPNLVSKSLQTTRRFDALKLWMTIESLGEELYGSMIDHGVKLT
REVADYIKATEGLELLVEPQFASVLFRVVPEGYPVEFIDSLNQNVADELFARGEANIGVTKVGNVQSLKMTTLSPVVTVD
NVKNLLAQVLAEAERIKDAIASGNYVPPID

Sequences:

>Translated_510_residues
MVDFAEHRKALLCNDAQSIADYESAMGEAVKAVSAWLQNEKMYTGGSIKELRSAISFQPSKEGMGVQQSLQRMIELFLNK
SLKVHHPHSLAHLHCPTMVMSQIAEVLINATNQSMDSWDQSPAGSLMEVQLIDWLRQKVGYGSGQAGVFTSGGTQSNLMG
VLLARDWCISKNWKDENGNPWSVQRDGIPAEAMKNVKVICSENAHFSVQKNMAMMGMGFQSVVTVPVNENAQMDVDALEK
TMAHLQAEGKVVACVVATAGTTDAGAIDPLKKIREITNKYGSWMHIDAAWGGALILSNDYRAMLDGIELSDSITLDFHKH
YFQSISCGAFLLKDEANYRFMHYEAEYLNSAYDEEHGVPNLVSKSLQTTRRFDALKLWMTIESLGEELYGSMIDHGVKLT
REVADYIKATEGLELLVEPQFASVLFRVVPEGYPVEFIDSLNQNVADELFARGEANIGVTKVGNVQSLKMTTLSPVVTVD
NVKNLLAQVLAEAERIKDAIASGNYVPPID
>Mature_510_residues
MVDFAEHRKALLCNDAQSIADYESAMGEAVKAVSAWLQNEKMYTGGSIKELRSAISFQPSKEGMGVQQSLQRMIELFLNK
SLKVHHPHSLAHLHCPTMVMSQIAEVLINATNQSMDSWDQSPAGSLMEVQLIDWLRQKVGYGSGQAGVFTSGGTQSNLMG
VLLARDWCISKNWKDENGNPWSVQRDGIPAEAMKNVKVICSENAHFSVQKNMAMMGMGFQSVVTVPVNENAQMDVDALEK
TMAHLQAEGKVVACVVATAGTTDAGAIDPLKKIREITNKYGSWMHIDAAWGGALILSNDYRAMLDGIELSDSITLDFHKH
YFQSISCGAFLLKDEANYRFMHYEAEYLNSAYDEEHGVPNLVSKSLQTTRRFDALKLWMTIESLGEELYGSMIDHGVKLT
REVADYIKATEGLELLVEPQFASVLFRVVPEGYPVEFIDSLNQNVADELFARGEANIGVTKVGNVQSLKMTTLSPVVTVD
NVKNLLAQVLAEAERIKDAIASGNYVPPID

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI194294551, Length=428, Percent_Identity=30.8411214953271, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI197383062, Length=468, Percent_Identity=28.2051282051282, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI197276620, Length=431, Percent_Identity=28.3062645011601, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI4503875, Length=431, Percent_Identity=28.3062645011601, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI58331246, Length=428, Percent_Identity=26.4018691588785, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI92110055, Length=411, Percent_Identity=26.0340632603406, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI4503281, Length=356, Percent_Identity=25, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI132814448, Length=356, Percent_Identity=25, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71993062, Length=450, Percent_Identity=27.3333333333333, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17555682, Length=373, Percent_Identity=29.2225201072386, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71993058, Length=373, Percent_Identity=28.9544235924933, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17534817, Length=403, Percent_Identity=24.5657568238213, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17534819, Length=403, Percent_Identity=24.5657568238213, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551992, Length=448, Percent_Identity=21.875, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71981211, Length=458, Percent_Identity=19.4323144104804, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981217, Length=467, Percent_Identity=19.0578158458244, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI133931025, Length=431, Percent_Identity=21.5777262180974, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136594, Length=455, Percent_Identity=28.3516483516484, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21356415, Length=337, Percent_Identity=30.2670623145401, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24657193, Length=400, Percent_Identity=28, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24657185, Length=400, Percent_Identity=28, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24657188, Length=400, Percent_Identity=28, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI221476190, Length=460, Percent_Identity=24.3478260869565, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24585143, Length=460, Percent_Identity=24.3478260869565, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24585139, Length=462, Percent_Identity=24.6753246753247, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24652373, Length=407, Percent_Identity=24.5700245700246, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136190, Length=357, Percent_Identity=23.8095238095238, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24585135, Length=339, Percent_Identity=23.8938053097345, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24586044, Length=415, Percent_Identity=22.8915662650602, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573972, Length=360, Percent_Identity=23.3333333333333, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 56253; Mature: 56253

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00392 DDC_GAD_HDC_YDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDFAEHRKALLCNDAQSIADYESAMGEAVKAVSAWLQNEKMYTGGSIKELRSAISFQPS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCC
KEGMGVQQSLQRMIELFLNKSLKVHHPHSLAHLHCPTMVMSQIAEVLINATNQSMDSWDQ
CCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHCCC
SPAGSLMEVQLIDWLRQKVGYGSGQAGVFTSGGTQSNLMGVLLARDWCISKNWKDENGNP
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
WSVQRDGIPAEAMKNVKVICSENAHFSVQKNMAMMGMGFQSVVTVPVNENAQMDVDALEK
CEEECCCCCHHHHCCEEEEECCCCCEEHHCCHHHHCCCHHHEEEEECCCCCCCCHHHHHH
TMAHLQAEGKVVACVVATAGTTDAGAIDPLKKIREITNKYGSWMHIDAAWGGALILSNDY
HHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCH
RAMLDGIELSDSITLDFHKHYFQSISCGAFLLKDEANYRFMHYEAEYLNSAYDEEHGVPN
HHHHCCCCCCCCEEEHHHHHHHHHCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCHH
LVSKSLQTTRRFDALKLWMTIESLGEELYGSMIDHGVKLTREVADYIKATEGLELLVEPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
FASVLFRVVPEGYPVEFIDSLNQNVADELFARGEANIGVTKVGNVQSLKMTTLSPVVTVD
HHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCEEEHH
NVKNLLAQVLAEAERIKDAIASGNYVPPID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVDFAEHRKALLCNDAQSIADYESAMGEAVKAVSAWLQNEKMYTGGSIKELRSAISFQPS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCC
KEGMGVQQSLQRMIELFLNKSLKVHHPHSLAHLHCPTMVMSQIAEVLINATNQSMDSWDQ
CCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHCCC
SPAGSLMEVQLIDWLRQKVGYGSGQAGVFTSGGTQSNLMGVLLARDWCISKNWKDENGNP
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
WSVQRDGIPAEAMKNVKVICSENAHFSVQKNMAMMGMGFQSVVTVPVNENAQMDVDALEK
CEEECCCCCHHHHCCEEEEECCCCCEEHHCCHHHHCCCHHHEEEEECCCCCCCCHHHHHH
TMAHLQAEGKVVACVVATAGTTDAGAIDPLKKIREITNKYGSWMHIDAAWGGALILSNDY
HHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCH
RAMLDGIELSDSITLDFHKHYFQSISCGAFLLKDEANYRFMHYEAEYLNSAYDEEHGVPN
HHHHCCCCCCCCEEEHHHHHHHHHCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCHH
LVSKSLQTTRRFDALKLWMTIESLGEELYGSMIDHGVKLTREVADYIKATEGLELLVEPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
FASVLFRVVPEGYPVEFIDSLNQNVADELFARGEANIGVTKVGNVQSLKMTTLSPVVTVD
HHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCEEEHH
NVKNLLAQVLAEAERIKDAIASGNYVPPID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8772175 [H]