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The map label for this gene is lrp [H]

Identifier: 213158164

GI number: 213158164

Start: 2969682

End: 2970167

Strand: Direct

Name: lrp [H]

Synonym: AB57_2878

Alternate gene names: 213158164

Gene position: 2969682-2970167 (Clockwise)

Preceding gene: 213158155

Following gene: 213158168

Centisome position: 73.32

GC content: 37.65

Gene sequence:

>486_bases
ATGGATAAGTTCGACTGGCAAATCATTCAGGCACTACAAAAGAATGGACGACTCACCAATCAGGAAATTGGAGATTTAAT
CGGTTTATCTGCTTCTCAATGTTCAAGACGACGTCAATTGCTTGAGCAAAAGGGCGTGATTCTTGGCTACACGGCACGCA
TCCAGCAACAGGCGCTAGGGCTGGAAGTTACAGCGATGATTCACATAAACTTAAGAACACACGAGGCGAAATCACAGCAA
GCTTTCCAAGAGTTGATTGAAGCTGAAGATAACATTCAGGATGCTTTTTCAATTAGTGGTGATGCTGATTTTATTTTAAA
AGTCGTTGCTGAAAATTTAGAACAGCTTTCTCAATTTGTGACTGAAAGATTGCTTTCTTATAATTTTATAGGGCACATAA
AGTCTTACATTGTTCTGAAAAAAATTAAAGAACAGAATCATTTTTTAATCAAGCCTAAAAGCATGAGCTATCATCACTCT
CAATAA

Upstream 100 bases:

>100_bases
TAGAAAAATAATATTTCATCTATCTTTTAGATTTCGTGCATAATGAAAACGCATTTTAATAAAAATACATGATTTGTGTA
TCATAAAAGGATTTTATGCA

Downstream 100 bases:

>100_bases
AATAACTCAGCTTTTCACGCTTAAAAATGAAAATAAAAAAGGCGGATACTAAATCCGCCTTAAAATTAATATTTAGATTT
TACTAATATGGACCGTTTGT

Product: transcriptional regulator, AsnC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MDKFDWQIIQALQKNGRLTNQEIGDLIGLSASQCSRRRQLLEQKGVILGYTARIQQQALGLEVTAMIHINLRTHEAKSQQ
AFQELIEAEDNIQDAFSISGDADFILKVVAENLEQLSQFVTERLLSYNFIGHIKSYIVLKKIKEQNHFLIKPKSMSYHHS
Q

Sequences:

>Translated_161_residues
MDKFDWQIIQALQKNGRLTNQEIGDLIGLSASQCSRRRQLLEQKGVILGYTARIQQQALGLEVTAMIHINLRTHEAKSQQ
AFQELIEAEDNIQDAFSISGDADFILKVVAENLEQLSQFVTERLLSYNFIGHIKSYIVLKKIKEQNHFLIKPKSMSYHHS
Q
>Mature_161_residues
MDKFDWQIIQALQKNGRLTNQEIGDLIGLSASQCSRRRQLLEQKGVILGYTARIQQQALGLEVTAMIHINLRTHEAKSQQ
AFQELIEAEDNIQDAFSISGDADFILKVVAENLEQLSQFVTERLLSYNFIGHIKSYIVLKKIKEQNHFLIKPKSMSYHHS
Q

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=153, Percent_Identity=28.7581699346405, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=20.5298013245033, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18482; Mature: 18482

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFDWQIIQALQKNGRLTNQEIGDLIGLSASQCSRRRQLLEQKGVILGYTARIQQQALG
CCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHCC
LEVTAMIHINLRTHEAKSQQAFQELIEAEDNIQDAFSISGDADFILKVVAENLEQLSQFV
EEEEEEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TERLLSYNFIGHIKSYIVLKKIKEQNHFLIKPKSMSYHHSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MDKFDWQIIQALQKNGRLTNQEIGDLIGLSASQCSRRRQLLEQKGVILGYTARIQQQALG
CCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHCC
LEVTAMIHINLRTHEAKSQQAFQELIEAEDNIQDAFSISGDADFILKVVAENLEQLSQFV
EEEEEEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TERLLSYNFIGHIKSYIVLKKIKEQNHFLIKPKSMSYHHSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]