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The map label for this gene is degS [H]

Identifier: 213158063

GI number: 213158063

Start: 2845185

End: 2846360

Strand: Reverse

Name: degS [H]

Synonym: AB57_2775

Alternate gene names: 213158063

Gene position: 2846360-2845185 (Counterclockwise)

Preceding gene: 213158067

Following gene: 213158059

Centisome position: 70.27

GC content: 41.41

Gene sequence:

>1176_bases
GTGCGCCGCACCTTTACATGGTTACCTTGGGTGTTACTTATTATTGTAATTGCCAGTTTTATTGCATGGCAAAAATACCA
TCAGCCGAAACCAACTGTTGCAGTTGATGGGGTGCAAATGCCAGCTGAGAAAGTTGAGCCACTGGTTGATACTTCTCGAA
CGGGCGGGGTGGTGTCTTATAGTGCTGCGGTAAAAGTTGCAGCACCAGCAGTAGTTAATATTTTTACGACCCAGAAAGTT
AAACAAAATCATCCTTTATTAAGTGATCCAGTATTCCGTGAATTTTTTGGAAATCAGGTTCCTGAGCAACAACAGCAAAA
TGAAAATAGTTTAGGTTCAGGGGTTATTGTTCGCGCCGATGGTTATATTCTCACCAATAATCATGTGATTGCTCAAGCTG
ACCAGATTGTGGTGGCATTACATGATGGACGTCGAGCAGAAGCTACAATTGTTGGCACCGACCCTGATACAGATTTAGCG
GTTATTAAAATCGATTTAGATAAATTACCAGTATTGCCTTTTAAGCTCAGTGGTAATGAAGTTGGTGATGTTGTTTTAGC
GATTGGTAACCCATTTGGCGTAGGACAAACAGTCACTCAAGGGATTATTTCAGCAACGGGTCGCTCTGATTTAGGTATTA
ATACCTATGAAGACTTTATTCAAACTGATGCTGCAATTAACCCAGGTAACTCAGGTGGCGCATTAATCGATGTGGCTGGT
AACTTGATTGGTGTAAATACGGCGATTTTCTCACAATCGGGTGGCTCTTTAGGAATTGGCTTCGCGATTCCGGCAAAGGT
TTGTCAGCAAGTATTAAACTCGATTTTAAAAGATGGTCGTGTTGTTCGTGGTTGGTTGGGTATTAGTTTACTTCCACCTA
CACAAGACGATGTATTGGCACCTAAACAGCAAGTGGGTGTAGTTGTTGCTGATGTCTTAAAAAATGGTCCGGCAGATGCT
GCGGGGATTAAAGTTGGCGATAAAATTGTTCAGGTGAATAATGAGCCGATCACTTCAGCTTCTCATTTAATTAATTATGT
CGCTTTGCAAGCACCAAATAGCGAAATTAATGTTCTGGTTGAAAGAGAAGGTAAACAACAAAACTATGTTGTGACGGTAG
GTGAGCGAAAAGCACAGAATACACAATCTCAGTATATTCCGCTTCCAAGACGTTAA

Upstream 100 bases:

>100_bases
TATGTATATCGACATATTTAATTTAAAATGCTTAACTGAAAACTCTTTTTGTTCAATATATTAATTTAATTAAAAACTTC
TTTGCGTAGAGGATATGAAC

Downstream 100 bases:

>100_bases
AACCTAAATAAAAAAAGCCTCATTTTGAGGCTTTTTTTATTGTTGTTTATTAGGAGTGACTAAGACTTTGATGCTGATTT
TTAAATTCAGCTAAAGCTTC

Product: peptidase S1 and S6

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRRTFTWLPWVLLIIVIASFIAWQKYHQPKPTVAVDGVQMPAEKVEPLVDTSRTGGVVSYSAAVKVAAPAVVNIFTTQKV
KQNHPLLSDPVFREFFGNQVPEQQQQNENSLGSGVIVRADGYILTNNHVIAQADQIVVALHDGRRAEATIVGTDPDTDLA
VIKIDLDKLPVLPFKLSGNEVGDVVLAIGNPFGVGQTVTQGIISATGRSDLGINTYEDFIQTDAAINPGNSGGALIDVAG
NLIGVNTAIFSQSGGSLGIGFAIPAKVCQQVLNSILKDGRVVRGWLGISLLPPTQDDVLAPKQQVGVVVADVLKNGPADA
AGIKVGDKIVQVNNEPITSASHLINYVALQAPNSEINVLVEREGKQQNYVVTVGERKAQNTQSQYIPLPRR

Sequences:

>Translated_391_residues
MRRTFTWLPWVLLIIVIASFIAWQKYHQPKPTVAVDGVQMPAEKVEPLVDTSRTGGVVSYSAAVKVAAPAVVNIFTTQKV
KQNHPLLSDPVFREFFGNQVPEQQQQNENSLGSGVIVRADGYILTNNHVIAQADQIVVALHDGRRAEATIVGTDPDTDLA
VIKIDLDKLPVLPFKLSGNEVGDVVLAIGNPFGVGQTVTQGIISATGRSDLGINTYEDFIQTDAAINPGNSGGALIDVAG
NLIGVNTAIFSQSGGSLGIGFAIPAKVCQQVLNSILKDGRVVRGWLGISLLPPTQDDVLAPKQQVGVVVADVLKNGPADA
AGIKVGDKIVQVNNEPITSASHLINYVALQAPNSEINVLVEREGKQQNYVVTVGERKAQNTQSQYIPLPRR
>Mature_391_residues
MRRTFTWLPWVLLIIVIASFIAWQKYHQPKPTVAVDGVQMPAEKVEPLVDTSRTGGVVSYSAAVKVAAPAVVNIFTTQKV
KQNHPLLSDPVFREFFGNQVPEQQQQNENSLGSGVIVRADGYILTNNHVIAQADQIVVALHDGRRAEATIVGTDPDTDLA
VIKIDLDKLPVLPFKLSGNEVGDVVLAIGNPFGVGQTVTQGIISATGRSDLGINTYEDFIQTDAAINPGNSGGALIDVAG
NLIGVNTAIFSQSGGSLGIGFAIPAKVCQQVLNSILKDGRVVRGWLGISLLPPTQDDVLAPKQQVGVVVADVLKNGPADA
AGIKVGDKIVQVNNEPITSASHLINYVALQAPNSEINVLVEREGKQQNYVVTVGERKAQNTQSQYIPLPRR

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=287, Percent_Identity=34.4947735191638, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI22129776, Length=312, Percent_Identity=36.2179487179487, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7019477, Length=329, Percent_Identity=33.434650455927, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24308541, Length=280, Percent_Identity=35.3571428571429, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1789630, Length=329, Percent_Identity=44.6808510638298, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1789629, Length=310, Percent_Identity=41.6129032258065, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1786356, Length=328, Percent_Identity=41.4634146341463, Blast_Score=214, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24646839, Length=287, Percent_Identity=33.7979094076655, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011783
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 41735; Mature: 41735

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTFTWLPWVLLIIVIASFIAWQKYHQPKPTVAVDGVQMPAEKVEPLVDTSRTGGVVSY
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCHHHCCCCCCCEEEE
SAAVKVAAPAVVNIFTTQKVKQNHPLLSDPVFREFFGNQVPEQQQQNENSLGSGVIVRAD
ECEEEEECCEEEEEEEHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEC
GYILTNNHVIAQADQIVVALHDGRRAEATIVGTDPDTDLAVIKIDLDKLPVLPFKLSGNE
CEEEECCEEEEECCEEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEECCCC
VGDVVLAIGNPFGVGQTVTQGIISATGRSDLGINTYEDFIQTDAAINPGNSGGALIDVAG
CCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECC
NLIGVNTAIFSQSGGSLGIGFAIPAKVCQQVLNSILKDGRVVRGWLGISLLPPTQDDVLA
CEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCCCCCC
PKQQVGVVVADVLKNGPADAAGIKVGDKIVQVNNEPITSASHLINYVALQAPNSEINVLV
CHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHEEEEECCCCCEEEEE
EREGKQQNYVVTVGERKAQNTQSQYIPLPRR
EECCCCCCEEEEECCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MRRTFTWLPWVLLIIVIASFIAWQKYHQPKPTVAVDGVQMPAEKVEPLVDTSRTGGVVSY
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCHHHCCCCCCCEEEE
SAAVKVAAPAVVNIFTTQKVKQNHPLLSDPVFREFFGNQVPEQQQQNENSLGSGVIVRAD
ECEEEEECCEEEEEEEHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEC
GYILTNNHVIAQADQIVVALHDGRRAEATIVGTDPDTDLAVIKIDLDKLPVLPFKLSGNE
CEEEECCEEEEECCEEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEECCCC
VGDVVLAIGNPFGVGQTVTQGIISATGRSDLGINTYEDFIQTDAAINPGNSGGALIDVAG
CCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECC
NLIGVNTAIFSQSGGSLGIGFAIPAKVCQQVLNSILKDGRVVRGWLGISLLPPTQDDVLA
CEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCCCCCC
PKQQVGVVVADVLKNGPADAAGIKVGDKIVQVNNEPITSASHLINYVALQAPNSEINVLV
CHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHEEEEECCCCCEEEEE
EREGKQQNYVVTVGERKAQNTQSQYIPLPRR
EECCCCCCEEEEECCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]