| Definition | Acinetobacter baumannii AB0057, complete genome. |
|---|---|
| Accession | NC_011586 |
| Length | 4,050,513 |
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The map label for this gene is slt [H]
Identifier: 213157981
GI number: 213157981
Start: 3588876
End: 3590819
Strand: Reverse
Name: slt [H]
Synonym: AB57_3476
Alternate gene names: 213157981
Gene position: 3590819-3588876 (Counterclockwise)
Preceding gene: 213158785
Following gene: 213157980
Centisome position: 88.65
GC content: 41.87
Gene sequence:
>1944_bases ATGAAAAATAAATATGCACATCGTAGCTGGTTAGGAGCTGTGTGTTTACTTGGTTGTTCATTATCTTATGCCGCAGAAGA ACAATTTAACGATGCACTAAATGCCGCCAATAGTGGTAATACTGCATTGTTAGATCAATATCAGCTTGCAATGCAAAATG ATGTGTTGGGCTACTATCCTGAATATTGGAAATTAAACACGAATTTAGGCTTTCAATCTCCGACATCAATTGTAAGCTTC GCACAGCGCTATCCACAGTCTGCTATGGCAGAAAAGCTGGCCGCGGATTATGTCGAAGAAAAAGTTAAACAAGCTGACTT TGCGTCTGCACAACCAATCTTGCCTTATGTTTCGAATCCTGACCAAGCCGAAAATTGTGCTTTAGCGCAGGTGAGAGCTA AAAGTGGTGATGCATTAGTTTTTGCTGAATATAAAGATGTATGGTTAGCCACTGAATCGCAACCAGAATCATGTATTGGA CTCGGCCGTATGATGCTGTCTAGTCCATTAATGAGTACACAAGACAAGCAGCAGCGCCTGTGGGTACAGTTACGTGCAGG TTTATCTGGACAGGCGCTTGCTACAGCACAGACTTTGGGTTTGAATTTGTCTTTGGCTCAGCTCAATCAGATTCAGGCGA ATCCACTGAATTACTTGTGGTCAGCACCAAAAACCAATGACGTAGATTACGCCTATTTAATTTTTGCACTAGGCCGTTTA GCAAATAATGATTTAGGAAATGCTTTTGCAAATGTACAGCGAGTAGCGCAAGGCACTCCAGAGAGCGTGCAAAAGTATCT CTATCGAACCGTAGCCTATATTGGTGGAACTACGGTAATGAAAAACAACTTTAACCGTGAAGTCCTTCAATATTTTGACG CAAGTTATGGCTATCCGTTAAGTCCTGAAGAAGCTGAAATTTATGCACGACAAGCTATTCGTTTTAGTGCCTGGGAAAGT TTAATTCGTGCAATTGATAGTATGTCGGTTTCACAAAAACAAGAAGATCGCTGGCAATATTGGTTAGCGCGTGCGACAGA GCAACGTGGCGATAGTAATTCTAAAAACACGGCACAACGTATTTATAAAAAATTAGCTGAAACTGGGGATGATTATCACA ATCTTCTTGCAAAAGACCGTTTAGGCGTACGATATAATCATCAGCCGTATAATGATGAGCCAACTGCAAGTGATTTACGC CGTTTAGATCAAAATATTCACTTTAATCGTGCATTTACTTTAAGACGGATTAATGCCAACCCAACCTATACCAACCGAGA GTGGAACTGGGCTGTTCGTCAAGCATATCTTCAGCATGATGATGGATTACTATTAGCGGCGGCAAAACGTGCTCATGATA TGGGATGGTATGACCGCGCGATTTATGCGGCAGATCGTACAACGAATAAACATAATGATACGTATCGTTATGTGACCCCG CATAAGACCAATGTCGTAAGCCATAGTTACAATGCTGGAATTGATCCTGCTTGGGCTTATGGTTTAATGCGTCAAGAAAG CCGATTTGTTACCTCGGCACGCTCTCATGTAGGTGCTGGTGGACTTATGCAAATTATGCCAGATACGGCAAAGTTGATTG CTCGCCAGATGGGAGAAACATATAATCCGGCAGCGTTAAGTGAAATGAACACCAATATTCGTTATGGGACATTTTATTTA TCGATGATTCAAGGGCAATTAAGTAATAACCCTGTTTTAGCAACGGCAGGTTATAATGCTGGGCCGAATCGGGCAAGACG TTGGCAACCTGATTACCAACCGATTGAGGCTGATCAATATACAGAAACCATTCCATTGCTTGAGACCAGAGATTATGTCA AGCATGTCATGACGAATGCGACGCATTATGGAGTGATATTAGGTCAAGGTGCTCAATCATTAATACAACGTATGAAAGTC ATTCCAACGCGATCATCACCTTAG
Upstream 100 bases:
>100_bases AAGCATGAAGAATAATTAAACTATGCCTAAAGGTGGATAGTCAGGATTTAACGCATTTATGAGACCAGGTAAAAAGAGCT CATCAAACAAGAGTCGTGTG
Downstream 100 bases:
>100_bases TTTTAGATGATGAATGATGGAACATTCTTTTAATTGGCATAACCAAGTTTTAATTAAATGAAATATAGAGACCTAGGACT TCAATCAATATCGCAACTTG
Product: lytic transglycosylase, catalytic
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 647; Mature: 647
Protein sequence:
>647_residues MKNKYAHRSWLGAVCLLGCSLSYAAEEQFNDALNAANSGNTALLDQYQLAMQNDVLGYYPEYWKLNTNLGFQSPTSIVSF AQRYPQSAMAEKLAADYVEEKVKQADFASAQPILPYVSNPDQAENCALAQVRAKSGDALVFAEYKDVWLATESQPESCIG LGRMMLSSPLMSTQDKQQRLWVQLRAGLSGQALATAQTLGLNLSLAQLNQIQANPLNYLWSAPKTNDVDYAYLIFALGRL ANNDLGNAFANVQRVAQGTPESVQKYLYRTVAYIGGTTVMKNNFNREVLQYFDASYGYPLSPEEAEIYARQAIRFSAWES LIRAIDSMSVSQKQEDRWQYWLARATEQRGDSNSKNTAQRIYKKLAETGDDYHNLLAKDRLGVRYNHQPYNDEPTASDLR RLDQNIHFNRAFTLRRINANPTYTNREWNWAVRQAYLQHDDGLLLAAAKRAHDMGWYDRAIYAADRTTNKHNDTYRYVTP HKTNVVSHSYNAGIDPAWAYGLMRQESRFVTSARSHVGAGGLMQIMPDTAKLIARQMGETYNPAALSEMNTNIRYGTFYL SMIQGQLSNNPVLATAGYNAGPNRARRWQPDYQPIEADQYTETIPLLETRDYVKHVMTNATHYGVILGQGAQSLIQRMKV IPTRSSP
Sequences:
>Translated_647_residues MKNKYAHRSWLGAVCLLGCSLSYAAEEQFNDALNAANSGNTALLDQYQLAMQNDVLGYYPEYWKLNTNLGFQSPTSIVSF AQRYPQSAMAEKLAADYVEEKVKQADFASAQPILPYVSNPDQAENCALAQVRAKSGDALVFAEYKDVWLATESQPESCIG LGRMMLSSPLMSTQDKQQRLWVQLRAGLSGQALATAQTLGLNLSLAQLNQIQANPLNYLWSAPKTNDVDYAYLIFALGRL ANNDLGNAFANVQRVAQGTPESVQKYLYRTVAYIGGTTVMKNNFNREVLQYFDASYGYPLSPEEAEIYARQAIRFSAWES LIRAIDSMSVSQKQEDRWQYWLARATEQRGDSNSKNTAQRIYKKLAETGDDYHNLLAKDRLGVRYNHQPYNDEPTASDLR RLDQNIHFNRAFTLRRINANPTYTNREWNWAVRQAYLQHDDGLLLAAAKRAHDMGWYDRAIYAADRTTNKHNDTYRYVTP HKTNVVSHSYNAGIDPAWAYGLMRQESRFVTSARSHVGAGGLMQIMPDTAKLIARQMGETYNPAALSEMNTNIRYGTFYL SMIQGQLSNNPVLATAGYNAGPNRARRWQPDYQPIEADQYTETIPLLETRDYVKHVMTNATHYGVILGQGAQSLIQRMKV IPTRSSP >Mature_647_residues MKNKYAHRSWLGAVCLLGCSLSYAAEEQFNDALNAANSGNTALLDQYQLAMQNDVLGYYPEYWKLNTNLGFQSPTSIVSF AQRYPQSAMAEKLAADYVEEKVKQADFASAQPILPYVSNPDQAENCALAQVRAKSGDALVFAEYKDVWLATESQPESCIG LGRMMLSSPLMSTQDKQQRLWVQLRAGLSGQALATAQTLGLNLSLAQLNQIQANPLNYLWSAPKTNDVDYAYLIFALGRL ANNDLGNAFANVQRVAQGTPESVQKYLYRTVAYIGGTTVMKNNFNREVLQYFDASYGYPLSPEEAEIYARQAIRFSAWES LIRAIDSMSVSQKQEDRWQYWLARATEQRGDSNSKNTAQRIYKKLAETGDDYHNLLAKDRLGVRYNHQPYNDEPTASDLR RLDQNIHFNRAFTLRRINANPTYTNREWNWAVRQAYLQHDDGLLLAAAKRAHDMGWYDRAIYAADRTTNKHNDTYRYVTP HKTNVVSHSYNAGIDPAWAYGLMRQESRFVTSARSHVGAGGLMQIMPDTAKLIARQMGETYNPAALSEMNTNIRYGTFYL SMIQGQLSNNPVLATAGYNAGPNRARRWQPDYQPIEADQYTETIPLLETRDYVKHVMTNATHYGVILGQGAQSLIQRMKV IPTRSSP
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=648, Percent_Identity=24.6913580246914, Blast_Score=130, Evalue=2e-31,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 73038; Mature: 73038
Theoretical pI: Translated: 8.59; Mature: 8.59
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNKYAHRSWLGAVCLLGCSLSYAAEEQFNDALNAANSGNTALLDQYQLAMQNDVLGYYP CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC EYWKLNTNLGFQSPTSIVSFAQRYPQSAMAEKLAADYVEEKVKQADFASAQPILPYVSNP CCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC DQAENCALAQVRAKSGDALVFAEYKDVWLATESQPESCIGLGRMMLSSPLMSTQDKQQRL CCCCCCHHHHHCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHH WVQLRAGLSGQALATAQTLGLNLSLAQLNQIQANPLNYLWSAPKTNDVDYAYLIFALGRL HHHHHCCCCCCHHHHHHHHCCCEEHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHH ANNDLGNAFANVQRVAQGTPESVQKYLYRTVAYIGGTTVMKNNFNREVLQYFDASYGYPL HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCCCC SPEEAEIYARQAIRFSAWESLIRAIDSMSVSQKQEDRWQYWLARATEQRGDSNSKNTAQR CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH IYKKLAETGDDYHNLLAKDRLGVRYNHQPYNDEPTASDLRRLDQNIHFNRAFTLRRINAN HHHHHHHCCCHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCC PTYTNREWNWAVRQAYLQHDDGLLLAAAKRAHDMGWYDRAIYAADRTTNKHNDTYRYVTP CCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHEEEEECCCCCCCCCEEEEECC HKTNVVSHSYNAGIDPAWAYGLMRQESRFVTSARSHVGAGGLMQIMPDTAKLIARQMGET CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCC YNPAALSEMNTNIRYGTFYLSMIQGQLSNNPVLATAGYNAGPNRARRWQPDYQPIEADQY CCCHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH TETIPLLETRDYVKHVMTNATHYGVILGQGAQSLIQRMKVIPTRSSP HHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCC >Mature Secondary Structure MKNKYAHRSWLGAVCLLGCSLSYAAEEQFNDALNAANSGNTALLDQYQLAMQNDVLGYYP CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC EYWKLNTNLGFQSPTSIVSFAQRYPQSAMAEKLAADYVEEKVKQADFASAQPILPYVSNP CCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC DQAENCALAQVRAKSGDALVFAEYKDVWLATESQPESCIGLGRMMLSSPLMSTQDKQQRL CCCCCCHHHHHCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHH WVQLRAGLSGQALATAQTLGLNLSLAQLNQIQANPLNYLWSAPKTNDVDYAYLIFALGRL HHHHHCCCCCCHHHHHHHHCCCEEHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHH ANNDLGNAFANVQRVAQGTPESVQKYLYRTVAYIGGTTVMKNNFNREVLQYFDASYGYPL HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCCCC SPEEAEIYARQAIRFSAWESLIRAIDSMSVSQKQEDRWQYWLARATEQRGDSNSKNTAQR CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH IYKKLAETGDDYHNLLAKDRLGVRYNHQPYNDEPTASDLRRLDQNIHFNRAFTLRRINAN HHHHHHHCCCHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCC PTYTNREWNWAVRQAYLQHDDGLLLAAAKRAHDMGWYDRAIYAADRTTNKHNDTYRYVTP CCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHEEEEECCCCCCCCCEEEEECC HKTNVVSHSYNAGIDPAWAYGLMRQESRFVTSARSHVGAGGLMQIMPDTAKLIARQMGET CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCC YNPAALSEMNTNIRYGTFYLSMIQGQLSNNPVLATAGYNAGPNRARRWQPDYQPIEADQY CCCHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH TETIPLLETRDYVKHVMTNATHYGVILGQGAQSLIQRMKVIPTRSSP HHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]