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The map label for this gene is trxC [C]

Identifier: 213157939

GI number: 213157939

Start: 3539257

End: 3539694

Strand: Reverse

Name: trxC [C]

Synonym: AB57_3432

Alternate gene names: 213157939

Gene position: 3539694-3539257 (Counterclockwise)

Preceding gene: 213157940

Following gene: 213157938

Centisome position: 87.39

GC content: 41.55

Gene sequence:

>438_bases
ATGATTATTGTATGTGCATCGTGCGGTGCAAAAAATAGAGTACCAGAGGAAAAACTTACCGCTCAACCGAGTTGTGGACA
ATGTCATCAGCCATTACTCCCGCTTGCGCCAATTGAGTTAAATGAACAAAACTTTAGCAACTACATCACAAATAGTGATC
TGCCTATTTTGATAGATTTATGGGCAGAATGGTGCGGACCTTGTAAAATGATGGCGCCACATTTTGCACAAGTTGCAAAA
CAAAATCCACGTGTCATTTTTGCCAAGATTAATACCGAAGAGTCTCCTCGCTTAAGCCAAGCATTTAATGTGAGAAGTAT
TCCTACCCTTGTATTAATGAATAAAACCACAGAAGTTGCTCGAATGAGCGGCGCATTACGCGCGCCTGAATTGCAACAGT
GGCTAGATCAACAACTTCAAACGAATTTCGGGAGCTAA

Upstream 100 bases:

>100_bases
ATGGGATATGAAACATTTTGATATCTATCACGGTTCATGGTTTGAAAAAGCAGTGACGACCCAATTAGAATTTTTACATC
AGCATATAGGAGTGATGTAA

Downstream 100 bases:

>100_bases
GGTGTCAGAAGCTTATACCAAACCAGAAGGAATTTTATCCTTACAAACGATTGCCATGCCAGCAGATACAAACTGGAGTG
GTGATGTGTTTGGTGGGTGG

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIIVCASCGAKNRVPEEKLTAQPSCGQCHQPLLPLAPIELNEQNFSNYITNSDLPILIDLWAEWCGPCKMMAPHFAQVAK
QNPRVIFAKINTEESPRLSQAFNVRSIPTLVLMNKTTEVARMSGALRAPELQQWLDQQLQTNFGS

Sequences:

>Translated_145_residues
MIIVCASCGAKNRVPEEKLTAQPSCGQCHQPLLPLAPIELNEQNFSNYITNSDLPILIDLWAEWCGPCKMMAPHFAQVAK
QNPRVIFAKINTEESPRLSQAFNVRSIPTLVLMNKTTEVARMSGALRAPELQQWLDQQLQTNFGS
>Mature_145_residues
MIIVCASCGAKNRVPEEKLTAQPSCGQCHQPLLPLAPIELNEQNFSNYITNSDLPILIDLWAEWCGPCKMMAPHFAQVAK
QNPRVIFAKINTEESPRLSQAFNVRSIPTLVLMNKTTEVARMSGALRAPELQQWLDQQLQTNFGS

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=95, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788936, Length=140, Percent_Identity=35.7142857142857, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI87082331, Length=103, Percent_Identity=36.8932038834951, Blast_Score=86, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI212646193, Length=98, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319925, Length=85, Percent_Identity=37.6470588235294, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321648, Length=81, Percent_Identity=34.5679012345679, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323072, Length=81, Percent_Identity=37.037037037037, Blast_Score=68, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573567, Length=107, Percent_Identity=33.6448598130841, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24639068, Length=136, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 16193; Mature: 16193

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVCASCGAKNRVPEEKLTAQPSCGQCHQPLLPLAPIELNEQNFSNYITNSDLPILIDL
CEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCHHHH
WAEWCGPCKMMAPHFAQVAKQNPRVIFAKINTEESPRLSQAFNVRSIPTLVLMNKTTEVA
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEECCCHHHH
RMSGALRAPELQQWLDQQLQTNFGS
HHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIVCASCGAKNRVPEEKLTAQPSCGQCHQPLLPLAPIELNEQNFSNYITNSDLPILIDL
CEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCHHHH
WAEWCGPCKMMAPHFAQVAKQNPRVIFAKINTEESPRLSQAFNVRSIPTLVLMNKTTEVA
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEECCCHHHH
RMSGALRAPELQQWLDQQLQTNFGS
HHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8652661 [H]