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The map label for this gene is ilvE [H]

Identifier: 213157917

GI number: 213157917

Start: 3516588

End: 3517514

Strand: Reverse

Name: ilvE [H]

Synonym: AB57_3409

Alternate gene names: 213157917

Gene position: 3517514-3516588 (Counterclockwise)

Preceding gene: 213157918

Following gene: 213157916

Centisome position: 86.84

GC content: 40.99

Gene sequence:

>927_bases
ATGAATTTGGCTGATCGTGATGGTTTTATTTGGCAAGATGGACAATTAATTGATTGGCGTGATGCAAAGATTCACGTTTT
AACCCATACTTTACACTACAGTATGGGCGTATTTGAGGGTGTTCGTGCTTATGAAACTCCTAAAGGTACTGCAATTTTCC
GTCTTCAAGACCACACAAAACGTTTGTTAAATTCAGCAAAAATTTATCAAATGAAAGTGCCGTATGATCAAGCAGCGCTT
GAACAAGCACAAATCGATGTTGTTCGTGAAAATAAATTAGCTTCTTGCTATTTACGTCCACTGATCTGGATCGGTTCAGA
GAAACTTGGTATTGCAGCAACAAATAACACCATTCATGCCGCTGTTGCAGCATGGGCATGGGGTGCATATCTTGGTGATG
AAGCAATGGCGAAAGGTATTCGCGTTAAAACTTCATCATTTACTCACCATCATCCAAACGTGACCATGTGTAAAGCAAAA
GCATCTGGTAACTACACGTTGTCAATTCTTGCTCACCAAGAAGTTGCACATTCGGGTTACGATGAAGCAATGCTTATGGA
CCCACAAGGTTATGTATGCCAAGGTTCTGGTGAAAACGTATTCTTGATTAAAGATGGTGTTTTACACACTCCAGATATTG
CGGGTGGCGCACTTGACGGTATTACACGCCAAACAGTGATGACGATTGCTAAAGATCTTGGTTATGAAGTTGTTGAGCGT
CGTATTACGCGTGACGAATTCTATATTGCCGATGAAGCATTCTTCACAGGTACTGCTGCTGAAGTAACACCAATTCGTGA
ATACGATGACCGTCAAATCGGTGCGGGTTGCCGTGGCCCAATTACCACTGAAATCCAAAAGACTTTCTTTGATGCAGTTC
AAGGTAAAAATCCAAAATATGAACACTGGTTAACTTACGTAAAATAA

Upstream 100 bases:

>100_bases
TACCCGTGCGGTCGTTTGCAATTTATGGCAAAGATTAATAGACCCAACCGCCTCGGTTGAGTTGGATAGTGAATGATTTT
ATAACAATTTGGAGTGTTCC

Downstream 100 bases:

>100_bases
GTTAATCCGTTAACATGAAAAGGCGAACGTTGGTTTCGCCTTTTTATTTTTGGGTTAGGGAGCTTTTATGCATATTGTCT
ATGTCTCTGATGGTAAAGCA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNLADRDGFIWQDGQLIDWRDAKIHVLTHTLHYSMGVFEGVRAYETPKGTAIFRLQDHTKRLLNSAKIYQMKVPYDQAAL
EQAQIDVVRENKLASCYLRPLIWIGSEKLGIAATNNTIHAAVAAWAWGAYLGDEAMAKGIRVKTSSFTHHHPNVTMCKAK
ASGNYTLSILAHQEVAHSGYDEAMLMDPQGYVCQGSGENVFLIKDGVLHTPDIAGGALDGITRQTVMTIAKDLGYEVVER
RITRDEFYIADEAFFTGTAAEVTPIREYDDRQIGAGCRGPITTEIQKTFFDAVQGKNPKYEHWLTYVK

Sequences:

>Translated_308_residues
MNLADRDGFIWQDGQLIDWRDAKIHVLTHTLHYSMGVFEGVRAYETPKGTAIFRLQDHTKRLLNSAKIYQMKVPYDQAAL
EQAQIDVVRENKLASCYLRPLIWIGSEKLGIAATNNTIHAAVAAWAWGAYLGDEAMAKGIRVKTSSFTHHHPNVTMCKAK
ASGNYTLSILAHQEVAHSGYDEAMLMDPQGYVCQGSGENVFLIKDGVLHTPDIAGGALDGITRQTVMTIAKDLGYEVVER
RITRDEFYIADEAFFTGTAAEVTPIREYDDRQIGAGCRGPITTEIQKTFFDAVQGKNPKYEHWLTYVK
>Mature_308_residues
MNLADRDGFIWQDGQLIDWRDAKIHVLTHTLHYSMGVFEGVRAYETPKGTAIFRLQDHTKRLLNSAKIYQMKVPYDQAAL
EQAQIDVVRENKLASCYLRPLIWIGSEKLGIAATNNTIHAAVAAWAWGAYLGDEAMAKGIRVKTSSFTHHHPNVTMCKAK
ASGNYTLSILAHQEVAHSGYDEAMLMDPQGYVCQGSGENVFLIKDGVLHTPDIAGGALDGITRQTVMTIAKDLGYEVVER
RITRDEFYIADEAFFTGTAAEVTPIREYDDRQIGAGCRGPITTEIQKTFFDAVQGKNPKYEHWLTYVK

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=288, Percent_Identity=26.3888888888889, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI48994963, Length=301, Percent_Identity=43.8538205980066, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17565728, Length=324, Percent_Identity=26.2345679012346, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322002, Length=262, Percent_Identity=25.5725190839695, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322608, Length=283, Percent_Identity=24.3816254416961, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34430; Mature: 34430

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLADRDGFIWQDGQLIDWRDAKIHVLTHTLHYSMGVFEGVRAYETPKGTAIFRLQDHTK
CCCCCCCCEEEECCCEEECCCCEEEEEEEEHHHHHHHHHCHHHHCCCCCCEEEEECHHHH
RLLNSAKIYQMKVPYDQAALEQAQIDVVRENKLASCYLRPLIWIGSEKLGIAATNNTIHA
HHHCCCEEEEEECCCCHHHHHHHHHEEECCCCHHHHHHCEEEEECCCCEEEEEECCCHHH
AVAAWAWGAYLGDEAMAKGIRVKTSSFTHHHPNVTMCKAKASGNYTLSILAHQEVAHSGY
HHHHHHHHHHHCCHHHHCCEEEEECCCEECCCCEEEEEEECCCCEEEEEEEEHHHHHCCC
DEAMLMDPQGYVCQGSGENVFLIKDGVLHTPDIAGGALDGITRQTVMTIAKDLGYEVVER
CCEEEECCCCCEEECCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
RITRDEFYIADEAFFTGTAAEVTPIREYDDRQIGAGCRGPITTEIQKTFFDAVQGKNPKY
HHCCCCEEEECCCEECCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
EHWLTYVK
HHHEEECC
>Mature Secondary Structure
MNLADRDGFIWQDGQLIDWRDAKIHVLTHTLHYSMGVFEGVRAYETPKGTAIFRLQDHTK
CCCCCCCCEEEECCCEEECCCCEEEEEEEEHHHHHHHHHCHHHHCCCCCCEEEEECHHHH
RLLNSAKIYQMKVPYDQAALEQAQIDVVRENKLASCYLRPLIWIGSEKLGIAATNNTIHA
HHHCCCEEEEEECCCCHHHHHHHHHEEECCCCHHHHHHCEEEEECCCCEEEEEECCCHHH
AVAAWAWGAYLGDEAMAKGIRVKTSSFTHHHPNVTMCKAKASGNYTLSILAHQEVAHSGY
HHHHHHHHHHHCCHHHHCCEEEEECCCEECCCCEEEEEEECCCCEEEEEEEEHHHHHCCC
DEAMLMDPQGYVCQGSGENVFLIKDGVLHTPDIAGGALDGITRQTVMTIAKDLGYEVVER
CCEEEECCCCCEEECCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
RITRDEFYIADEAFFTGTAAEVTPIREYDDRQIGAGCRGPITTEIQKTFFDAVQGKNPKY
HHCCCCEEEECCCEECCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
EHWLTYVK
HHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]