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The map label for this gene is aspS [H]

Identifier: 213157906

GI number: 213157906

Start: 3505896

End: 3507674

Strand: Direct

Name: aspS [H]

Synonym: AB57_3398

Alternate gene names: 213157906

Gene position: 3505896-3507674 (Clockwise)

Preceding gene: 213157905

Following gene: 213157907

Centisome position: 86.55

GC content: 42.33

Gene sequence:

>1779_bases
ATGATGCGAACTCATTACTGTGGCTCTTTAACTGAAGCCCAAATCGACCAGACCGTTACATTATGCGGTTGGGTACATCG
TCGCCGTGACCATGGCGGTGTTATTTTCCTTGATATGCGTGACCGTGATGGTCTCGTTCAAGTGGTTATTGACCCAGATA
CTCCAGAAGCATTTGCAACTGCAGATAAAGCACGTTCTGAATATGTATTAAAAATTACAGGTCGTGTTCGTCGCCGTTAT
GAAGGTACTGAAAACCCAAATATGGTGAGTGGTCAAATCGAAGTTTTAGGCAAAGAAATCGAAGTTCTTGCTGCATCTGA
AACTCCACCATTCCCATTAAATGACGACACTATTAACGTGTCAGAAGAACACCGTTTAAAATATCGTTTCTTGGACATCC
GTCGTCCAGAAATGTTAGAGCGTTTACGCTTCCGTTCTAAAGTAACCAACTTGATTCGTAACTATTTAGACGATCATGGT
TTCTTAGACGTTGAAACTCCGATTTTAACTCGTGCAACCCCTGAAGGTGCGCGTGACTATTTAGTACCAAGCCGTGTACA
AAATGGTAGCTTCTATGCACTTCCACAATCACCACAATTGTTCAAACAATTATTGATGGTTGGTGGTATTGATCGCTACT
ACCAAATCGCGAAATGTTTCCGTGATGAAGACTTACGTGCTGACCGTCAGCCTGAATTCACTCAAATCGACATTGAAACA
TCGTTCTTAAACGACGATGACATTATGGATTTGATGGAAGGCATGACTGTTAAATTATTTAACGACTTGCTTGGCGTAAA
ATTTGAAAAATTCCGCCGTATGCCATACAGCGAAGCAATGCGTGATTATGCATCTGACAAACCAGACTTGCGTATTCCGT
TAAAACTCGTTGATGTTGCAGACTTAATGCAAGAAGTTGAGTTCAAAGTATTTGCAGGTCCAGCTAAAGACCCTAAAGGC
CGTATTGCAGCACTTCGTGTACCGGGCGCAGGTTCATTAACACGTAGTCAAATTGATGAATACACTAAATTTGTCGGTAT
CTACGGTGCAAAAGGCTTAGCGTACATTAAAGTCAATGAAATCGAAAAAGGAATTGAAGGTCTTCAATCTCCTATCGTTA
AATTCATCGAACCAATCGTAATGCAATTGCTTGAACGTGTTGGCGCTGAAAATGGCGATATCGTATTCTTTGGTGCGGAC
AAAGCTAAAATTGTAAATGATGCAATGGGTGCACTTCGTGTCAAGATCGGTCATGACTTGAACCTTGCGACTTGTGAGTG
GGCTCCACTTTGGGTTGTTGACTTCCCAATGTTTGAAGAAACTGACGATGGCAAATGGACTTCTGTTCACCATCCATTCA
CATTACCTAAATCTAGTGTAGAAGACGTGAAGAGCAATCCAGGCGAAGCACTTTCTGTTGCTTACGACATGGTATTGAAC
GGTACTGAAGTTGGTGGTGGTTCACTTCGTATTTACACATTAGAAATGCAAAAAGCGATTTTTGAAGCGCTTGGTATTTC
CGATGAAGAAGCAGAAGAAAAATTCAGCTTCTTACTCAATGCGCTTCGTTACGGTGCACCTCCTCACGGTGGTTTGGCAT
TTGGTCTTGACCGTTTAGTAATGCTTATGACTGGCGCGACTTCAATTCGTGATGTTATTGCGTTCCCTAAAACGAAAACT
GCTGAATGTCCACTTACTCAAGCACCGGCTCCTGTTGAAGCAAACCAGCTTCGTGACTTGGGCATCCGCTTACGTGAACA
ACAAAAGAAAGAAGCTTAA

Upstream 100 bases:

>100_bases
GCATGCCATTCAACAGGGCATAATCGAAAACTTATTTTTTTGACGGTGCGCGGTTTACGCATCCGTCTTTTCAGCCAATA
TAGTTTGGATAATCTTCATC

Downstream 100 bases:

>100_bases
TTGCTCTCTAATAAAAAACCCTGCAATTGCAGGGTGTTTTATTAGACGGTCTCAAACAAACATTCGGTTTTTATAAGCTA
TGCTTTGCGAAAAAGCACGT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFATADKARSEYVLKITGRVRRRY
EGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINVSEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHG
FLDVETPILTRATPEGARDYLVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIET
SFLNDDDIMDLMEGMTVKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVADLMQEVEFKVFAGPAKDPKG
RIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNEIEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGAD
KAKIVNDAMGALRVKIGHDLNLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLN
GTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLVMLMTGATSIRDVIAFPKTKT
AECPLTQAPAPVEANQLRDLGIRLREQQKKEA

Sequences:

>Translated_592_residues
MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFATADKARSEYVLKITGRVRRRY
EGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINVSEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHG
FLDVETPILTRATPEGARDYLVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIET
SFLNDDDIMDLMEGMTVKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVADLMQEVEFKVFAGPAKDPKG
RIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNEIEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGAD
KAKIVNDAMGALRVKIGHDLNLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLN
GTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLVMLMTGATSIRDVIAFPKTKT
AECPLTQAPAPVEANQLRDLGIRLREQQKKEA
>Mature_592_residues
MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFATADKARSEYVLKITGRVRRRY
EGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINVSEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHG
FLDVETPILTRATPEGARDYLVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIET
SFLNDDDIMDLMEGMTVKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVADLMQEVEFKVFAGPAKDPKG
RIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNEIEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGAD
KAKIVNDAMGALRVKIGHDLNLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLN
GTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLVMLMTGATSIRDVIAFPKTKT
AECPLTQAPAPVEANQLRDLGIRLREQQKKEA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=608, Percent_Identity=39.6381578947368, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI5031815, Length=261, Percent_Identity=28.735632183908, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI194272210, Length=261, Percent_Identity=28.735632183908, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI45439306, Length=272, Percent_Identity=26.4705882352941, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4758762, Length=283, Percent_Identity=26.1484098939929, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI1788173, Length=586, Percent_Identity=59.0443686006826, Blast_Score=728, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=291, Percent_Identity=25.4295532646048, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790571, Length=293, Percent_Identity=25.2559726962457, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566633, Length=607, Percent_Identity=37.0675453047776, Blast_Score=339, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI71994340, Length=310, Percent_Identity=26.4516129032258, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535927, Length=310, Percent_Identity=26.4516129032258, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17535925, Length=310, Percent_Identity=26.4516129032258, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551876, Length=267, Percent_Identity=25.8426966292135, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71984122, Length=292, Percent_Identity=25.6849315068493, Blast_Score=78, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=638, Percent_Identity=31.8181818181818, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6320242, Length=271, Percent_Identity=25.830258302583, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=270, Percent_Identity=26.2962962962963, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321807, Length=247, Percent_Identity=25.9109311740891, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324256, Length=176, Percent_Identity=27.8409090909091, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584738, Length=598, Percent_Identity=37.7926421404682, Blast_Score=346, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24640849, Length=272, Percent_Identity=28.6764705882353, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640851, Length=272, Percent_Identity=28.6764705882353, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136276, Length=235, Percent_Identity=28.0851063829787, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 66668; Mature: 66668

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFAT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCHHHHH
ADKARSEYVLKITGRVRRRYEGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINV
HHHCCCCEEEEEEHHHHHHCCCCCCCCEECCHHEEECCEEEEEEECCCCCCCCCCCEECC
SEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHGFLDVETPILTRATPEGARDY
CHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCC
LVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIET
CCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
SFLNDDDIMDLMEGMTVKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVA
EECCCHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCEECHHHHHHH
DLMQEVEFKVFAGPAKDPKGRIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNE
HHHHHCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEECCCCEEEEEHHH
IEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGADKAKIVNDAMGALRVKIGHDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHEEEEECCCC
NLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLN
CEEEECCCEEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHCC
GTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLV
CCEECCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MLMTGATSIRDVIAFPKTKTAECPLTQAPAPVEANQLRDLGIRLREQQKKEA
HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFAT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCHHHHH
ADKARSEYVLKITGRVRRRYEGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINV
HHHCCCCEEEEEEHHHHHHCCCCCCCCEECCHHEEECCEEEEEEECCCCCCCCCCCEECC
SEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHGFLDVETPILTRATPEGARDY
CHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCC
LVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIET
CCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
SFLNDDDIMDLMEGMTVKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVA
EECCCHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCCEECHHHHHHH
DLMQEVEFKVFAGPAKDPKGRIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNE
HHHHHCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEECCCCEEEEEHHH
IEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGADKAKIVNDAMGALRVKIGHDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHEEEEECCCC
NLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLN
CEEEECCCEEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHCC
GTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLV
CCEECCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MLMTGATSIRDVIAFPKTKTAECPLTQAPAPVEANQLRDLGIRLREQQKKEA
HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA