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The map label for this gene is cysH [H]

Identifier: 213157793

GI number: 213157793

Start: 3375775

End: 3376509

Strand: Direct

Name: cysH [H]

Synonym: AB57_3276

Alternate gene names: 213157793

Gene position: 3375775-3376509 (Clockwise)

Preceding gene: 213157791

Following gene: 213157794

Centisome position: 83.34

GC content: 42.45

Gene sequence:

>735_bases
ATGACCGTTATTCCGACTATTGATATCGTTGATGCTCTCGCGGCTGAATATGCAGCTAAAAGTCCGCGCGAGATTCTAGA
ACTTGCATTAAGCCAACAAGGTGAGATTGCAATTTCGTTCTCTGGAGCAGAAGATGTAGTCTTAATTGATATGGCTTCAC
GTTTAGGTAAACCTTTCCGTGTTTTTAGTCTTGATACAGGCCGTCTACACCCTGAAACTTATCAATTTATTGAAACTGTT
CGTAAGCACTACAATATTAATATCGAGATTTGTTTCCCTGATGCGGAAGCTGTGCAAAGCATGGTGAATGAAAAAGGCTT
ATTTAGTTTCTTTAAAGATGGACATCAAGAATGCTGTGGCATACGAAAAGTTCAACCTTTACGTAAGAAACTGGCGACCT
TAGATGGCTGGATTACAGGTCAGCGTAAAGATCAAAGCCCTGGTACACGTACTGAAATTCCAGTGGTACAAGCTGATGCA
GGCTTCTCTGGTCCGGGTAAGCAACTCATTAAATATAATCCGCTTGCCAACTGGTCTAGCGCCGATGTGTGGAGTTATAT
CCGCATGATGGAAATTCCATATAACCCTCTACACGAGCGTGGTTTTGTTTCGATTGGTTGTGAGCCATGTACACGTCCAG
TACTTCCAAATCAACATGAACGTGAAGGCCGTTGGTGGTGGGAAGAAGCAACACAAAAAGAATGTGGCTTACATGCAGGT
AACTTGAAAAAATAG

Upstream 100 bases:

>100_bases
ATTCATAAGGATCGAAATTAAAGTGCTAAGCAATTTATTCACTATCCTTTAGAATATTTTTCATAACTCAATGCGCCCAA
GCCTTTTGCCAGGAACACCC

Downstream 100 bases:

>100_bases
TTCGGTATAAAAAAACCACTGATGAATCAGTGGTTTTTTTACAGTTATATCTCGTACACAAAGTCATATTTAATCTGTAA
TAAACGCTATATACTAAATT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTVIPTIDIVDALAAEYAAKSPREILELALSQQGEIAISFSGAEDVVLIDMASRLGKPFRVFSLDTGRLHPETYQFIETV
RKHYNINIEICFPDAEAVQSMVNEKGLFSFFKDGHQECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRTEIPVVQADA
GFSGPGKQLIKYNPLANWSSADVWSYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAG
NLKK

Sequences:

>Translated_244_residues
MTVIPTIDIVDALAAEYAAKSPREILELALSQQGEIAISFSGAEDVVLIDMASRLGKPFRVFSLDTGRLHPETYQFIETV
RKHYNINIEICFPDAEAVQSMVNEKGLFSFFKDGHQECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRTEIPVVQADA
GFSGPGKQLIKYNPLANWSSADVWSYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAG
NLKK
>Mature_243_residues
TVIPTIDIVDALAAEYAAKSPREILELALSQQGEIAISFSGAEDVVLIDMASRLGKPFRVFSLDTGRLHPETYQFIETVR
KHYNINIEICFPDAEAVQSMVNEKGLFSFFKDGHQECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRTEIPVVQADAG
FSGPGKQLIKYNPLANWSSADVWSYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAGN
LKK

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=247, Percent_Identity=27.5303643724696, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325425, Length=210, Percent_Identity=30.4761904761905, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27520; Mature: 27389

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIPTIDIVDALAAEYAAKSPREILELALSQQGEIAISFSGAEDVVLIDMASRLGKPFR
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHCCCCEE
VFSLDTGRLHPETYQFIETVRKHYNINIEICFPDAEAVQSMVNEKGLFSFFKDGHQECCG
EEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IRKVQPLRKKLATLDGWITGQRKDQSPGTRTEIPVVQADAGFSGPGKQLIKYNPLANWSS
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCC
ADVWSYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAG
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
NLKK
CCCC
>Mature Secondary Structure 
TVIPTIDIVDALAAEYAAKSPREILELALSQQGEIAISFSGAEDVVLIDMASRLGKPFR
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHCCCCEE
VFSLDTGRLHPETYQFIETVRKHYNINIEICFPDAEAVQSMVNEKGLFSFFKDGHQECCG
EEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IRKVQPLRKKLATLDGWITGQRKDQSPGTRTEIPVVQADAGFSGPGKQLIKYNPLANWSS
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCC
ADVWSYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAG
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
NLKK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA